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Plant gene targeting and gene replacement: application to crop genetic improvement
Published online by Cambridge University Press: 01 October 2008
Abstract
Recent advances and limitations of using zinc finger nuclease to stimulate a high efficiency of homologous recombination, and chimeric oligonucleotides to promote single base replacement in functional genomic research and plant genetic breeding, are systematically reviewed. Approaches to improve gene targeting efficiency through molecular modification of key pathways in plant homologous recombination are also discussed.
Keywords
- Type
- Review Article
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- Copyright © China Agricultural University 2008
Footnotes
First published in Journal of Agricultural Biotechnology 2007, 15(6): 1058–1065