Alzheimer is a progressive neurodegenerative disease with a variety of symptoms. Illustrative art teaching and Compound sea snake capsule are considered as potential therapeutic methods, but there is a lack of research on the therapeutic effect of the combination of the two.

50 patients with Alzheimer’s disease were randomly divided into experimental group and control group. The experimental group received illustration art teaching and Compound sea snake capsule treatment, and the control group received conventional treatment. The treatment period was 12 weeks. Cognitive function was assessed by the Alzheimer’s Disease Assessment Scale - Cognitive Subscale (ADAS-Cog) and Mini-Mental State Examination (MMSE), and statistical analysis was carried out with SPSS23.0.

In the experimental group, ADAS-Cog scores were 34.2±3.6 and 28.5±4.1, and MMSE scores were 19.8±2.1 and 22.4±2.4. In the control group, the ADAS-Cog scores were 34.5±3.9 and 33.8±4.2, and the MMSE scores were 19.5±2.3 and 19.7±2.6. T-test of independent sample showed that the scores of the experimental group after treatment were significantly lower than those before treatment (P<0.05), while the scores of the control group were not significantly different before and after treatment (P>0.05).

Illustration art teaching combined with compound Hai snake capsule is significant in the treatment of Alzheimer’s disease. The cognitive and mental functions of the experimental group improved significantly, while the control group did not change. Therefore, the combination therapy can be used as an effective adjunctive therapy to manage Alzheimer’s disease.

National Social Science Fund Arts Projects (No.20ZD28); Research Topic of Modern Education Technology of Jiangsu Province (Key Subject), Based on the interaction between teachers and students study of modern information technology (No.2019-R-79374); The Ministry of Education Cooperative Education Project (No.202102300015).