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The therapeutic effect of Mongolian medicine based on Qiwei Guangzao pill on depression

Published online by Cambridge University Press:  27 October 2023

Yuanyuan Wu
Affiliation:
Inner Mongolia Minzu University, Tongliao 028000, China
Lan Du
Affiliation:
Inner Mongolia Minzu University, Tongliao 028000, China
Anggelima
Affiliation:
Inner Mongolia Minzu University, Tongliao 028000, China
Ling Ling
Affiliation:
Inner Mongolia Minzu University, Tongliao 028000, China
Shan Tong
Affiliation:
Affiliated Hospital of Inner Mongolia Minzu University, Tongliao 028007, China
Huan Wang*
Affiliation:
Inner Mongolia Minzu University, Tongliao 028000, China National Medical Products Administration Key Laboratory of Quality Control of Traditional Chinese Medicine (Mongolian Medicine), Tongliao 028000, China
*
*Corresponding author.
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Abstract

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Background

The fast pace of modern life and work competition has led to an increase in the incidence rate of depression year by year. In recent years, Mongolian medicine has achieved good results in the treatment of depression. Research on the production of Mongolian medicine group based on Qiwei Guangzao pill to explore its therapeutic effect on moderate depression.

Subjects and Methods

The study selected 70 patients with moderate depression and randomly divided them into an experimental group and a control group. The experimental group received Mongolian medicine based on Qiwei Guangzao pills in the morning, middle, and evening, supplemented by droperidol and melitracen tablets; The control group only received oral administration of flupentixol and melitracin tablets. The treatment course was 4 weeks, and the patient’s status was evaluated by Hamilton Depression Scale (HAMD) score. SPSS25.0 software was used for statistical analysis of the data obtained.

Results

Compared to the control group, the rehabilitation rate of patients in the experimental group was 14.3%, and the proportion of patients with significant treatment effects was 45.8%. The total effective rate was about 91.4%, indicating that the improvement of HAMD scores in the experimental group was higher than that in the control group.

Conclusions

The experimental results show that the Mongolian medicine group based on Qiwei Guangzao pill has a significant therapeutic effect on moderate depression, and can effectively improve patients’ sleep status and gastrointestinal symptoms.

Acknowledgement

The National Natural Science Foundation of China, Correlational study on Lianqiao-4 and intestinal flora in the treatment of liver injury by the theory of “ essence and dross decomposition” (Grant No. 82060910); The National Natural Science Foundation for Young Scientists of China, Study on genomics and proteomics mechanism of Lianqiao-4 against liver injury based on the theory of “ essence and dross decomposition “ in Mongolian Medicine (Grant No. 81760765); The central government supported cross-disciplinary projects with special funds for local construction (No. JCHXKXM001).

Type
Abstracts
Copyright
© The Author(s), 2023. Published by Cambridge University Press