Hostname: page-component-848d4c4894-4rdrl Total loading time: 0 Render date: 2024-06-15T03:50:55.106Z Has data issue: false hasContentIssue false
  • English
  • Français

Familial dyslexia: neurocognitive and genetic correlation in a large Finnish family

Published online by Cambridge University Press:  16 September 2002

Jaana Nopola-Hemmi ,
Birgitta Myllyluoma ,
Arja Voutilainen ,
Seija Leinonen ,
Juha Kere  and
Timo Ahonen
Jaana Nopola-Hemmi
Affiliation:
Department of Paediatric Neurology, Hospital for Children and Adolescents, University of Helsinki, Finland.
Birgitta Myllyluoma
Affiliation:
Department of Paediatric Neurology, Hospital for Children and Adolescents, University of Helsinki, Finland.
Arja Voutilainen
Affiliation:
Department of Paediatric Neurology, Hospital for Children and Adolescents, University of Helsinki, Finland.
Seija Leinonen
Affiliation:
Niilo Mäki Institute, University of Jyväskylä, Jyväskylä, Finland.
Juha Kere
Affiliation:
Department of Medical Genetics, Biomedicum, University of Helsinki, Finland.
Timo Ahonen
Affiliation:
Niilo Mäki Institute, University of Jyväskylä, Jyväskylä, Finland.
Get access

Abstract

Neuropsychological findings of individuals with dyslexia (n=24) from a large, three-generation Finnish family are presented. We have previously performed whole genome linkage scanning in this family and found that dyslexia in this kindred segregates with a single locus in the pericentromeric area of chromosome 3. Those included in the analyses were carefully evaluated for general cognitive ability, reading and spelling skills, and reading-related neurocognitive skills. The neurocognitive type of dyslexia segregating in this family consisted of deficits in phonological awareness, verbal short-term memory, and rapid naming. Severe dyslexia also seemed to be connected with a general language difficulty and was most common in the eldest generation.

Type
Original Articles
Information
Developmental Medicine and Child Neurology , Volume 44 , Issue 9 , September 2002 , pp. 580 - 586
Copyright
© 2002 Mac Keith Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)