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No relationship between testosterone levels and depressive symptoms in aging men

Published online by Cambridge University Press:  16 April 2020

Yasuhiro Kaneda  and
Akira Fujii
Yasuhiro Kaneda*
Affiliation:
Department of Neuropsychiatry, The University of Tokushima School of Medicine, Tokushima, Japan Department of Neuropsychiatry, Fujii Hospital, Fujii, Japan
Akira Fujii
Affiliation:
Department of Neuropsychiatry, Fujii Hospital, Fujii, Japan
*
*Present address: Psychopharmacology Division, Psychiatric Hospital at Vanderbilt, 1601 23rd Avenue South, Suite 306, Nashville,TN 37212, USA. E-mail address:kaneday@clin.med.tokushima-u.ac.jp (Y. Kaneda).
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Summary

We investigated the associations between depression and serum testosterone levels in the elderly. There was no significant difference in the mean levels of the serum testosterone between the groups of patients and normals. For both groups, there was no significant correlation between testosterone and total depression scores or age.

Keywords

DepressionTestosteroneAge
Type
Short communication
Information
European Psychiatry , Volume 17 , Issue 7 , November 2002 , pp. 411 - 413
Copyright
Copyright © Éditions scientifiques et médicales Elsevier SAS 2002

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References

American Psychiatric Association Diagnostic and statistical manual of mental disorders, 4th ed (DSM-IV).Washington DC: American Psychiatric Association; 1994.Google Scholar
Fukuda, K.Kobayashi, S.A study on a self-rating depression scale. Seishin Shinkeigaku Zasshi (Psychiat Neurol Jpn) 1973;75:673–679 〚in Japanese〛Google Scholar
Gray, A.Berlin, J.A.McKinlay, J.B.Longcope, C.An examination of research design effects on the association of testosterone and male aging: results of a meta-analysis. J Clin Epidemiol 1991;44:671–684CrossRefGoogle ScholarPubMed
Levitt, A.J.Joffe, R.T.Total and free testosterone in depressed men. Acta Psychiatr Scand 1988;77:346–348CrossRefGoogle ScholarPubMed
Livingston, G.Hawkins, A.Graham, N.Blizard, B.Mann, A.The Gospel oak study: prevalence rates of dementia, depression and activity limitation among elderly residents in inner London. Psychol M 1990;20:137–146CrossRefGoogle ScholarPubMed
Mason, J.W.Giller, E.L.Kosten, T.R.Serum testosterone differences between patients with schizophrenia and those with affective disorder. Biol Psychiatry 1988;23:357–366CrossRefGoogle ScholarPubMed
Rubin, R.T.Poland, R.E.Lesser, I.M.Neuroendocrine aspects of primary endogenous depression VIII. Pituitary-gonadal axis activity in male patients and matched control subjects. Psychoneuroendocrinology 1989;14:217–229CrossRefGoogle ScholarPubMed
Rupprecht, R.Rupprecht, C.Rupprecht, M.Noder, M.Schwarz, W.Different reactivity of the hypothalamo-pituitary-gonadal-axis in depression and normal controls. Pharmacopsychiatry 1988;21:438–439CrossRefGoogle ScholarPubMed
Sachar, E.J.Halpern, F.Rosenfeld, R.S.Galligher, T.F.Hellman, L.Plasma and urinary testosterone levels in depressed men. Arch Gen Psychiatry 1973;28:15–18CrossRefGoogle ScholarPubMed
Undén, F.Ljunggren, J.G.Beck-Friis, J.Kjellman, B.F.Wetterberg, L.Hypothalamic-pituitary-gonadal axis in major depressive disorders. Acta Psychiat Scand 1988;78:138–146CrossRefGoogle ScholarPubMed
Vermeulen, A.Kaufman, J.M.Giagulli, V.A.Influence of some biological indexes on sex hormone-binding globulin and androgen levels in aging or obese males. J Clin Endocrinol Metab 1996;81:1821–1826Google ScholarPubMed
Vogel, W.Klaiber, E.L.Broverman, D.M.Roles of the gonadal steroid hormones in psychiatric depression in men and women. Prog Neuro-Psychopharmacol 1978;2:487–503CrossRefGoogle Scholar
Yesavage, J.A.Davidson, J.Widrow, L.Berger, P.A.Plasma testosterone levels, depression, sexuality, and age. Biol Psychiatry 1985;20:222–225CrossRefGoogle ScholarPubMed
Zung, W.W.Durham, N.C.A self-rating depression scale. Arch Gen Psychiatry 1965;12:63–70CrossRefGoogle ScholarPubMed
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