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A one year prevalence study of schizophrenia on Reunion Island

Published online by Cambridge University Press:  16 April 2020

M Jay
Affiliation:
Saint Paul Psychiatric Hospital, Reunion Island, France
P Gorwood*
Affiliation:
Genetic Epidemiology, INSERM Unit 155, Université Paris VII, Paris, France Psychiatric Department, Louis Mourier Hospital, 178, rue des Renouillers, 92701Colombes, France
J Feingold
Affiliation:
Psychiatric Department, Louis Mourier Hospital, 178, rue des Renouillers, 92701Colombes, France
M Leboyer
Affiliation:
Psychiatric Department, Louis Mourier Hospital, 178, rue des Renouillers, 92701Colombes, France Psychiatric Department, Pitié-Salpêtrière Hospital, Paris, France
*
*Correspondence and reprints to the Colombes address.
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Summary

Review of geographical comparisons of the prevalence of schizophrenic disorders found a ten-fold range difference between geographical contiguous groups, with high and low prevalence pockets. We performed a 1-year prevalence study of schizophrenia in a limited area of Reunion Island in the Indian Ocean, and analysed the prevalence variability in contiguous regions of this area. We found one of the highest reported age-corrected (above 15 years) 1-year prevalence of schizophrenia (14.9 per thousand). Large discrepancies in the distribution of prevalence rates of schizophrenia were observed between the five towns analysed. Interestingly, when a higher prevalence was observed, it was highly correlated with an increase of the percentage of familial cases (r = 0.989, df = 3, P = 0.0014). Presence of founder effect often described in geographical isolates could explain the high prevalence rate and the heterogeneity between towns observed in our sample.

Type
Original article
Copyright
Copyright © European Psychiatric Association 1997

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References

Andreassen, NCEndicott, JSpitzer, RLWinokur, GThe family history method using diagnostic criteria: reliability and vali-dity. Arch Gen Psychiatry 1977; 34: 12291235CrossRefGoogle Scholar
Beckmann, JSRichard, IHillaire, D, et al.A gene for limb-girdle muscular dystrophy maps to chromosome 15 by Lin-kage. CR Acad Sci Paris SER III–VIE 1991; 312: 141148Google Scholar
Ben-Tovim, DCushnie, JThe prevalence of schizophrenia in a remote area of Bostwana. Br J Psychiatry 1986; 148: 576580CrossRefGoogle Scholar
Book, JAWetterberg, LModrzewska, KSchizophrenia in a North Swedish geographical isolate 19001977: epidemio-logy, genetics and bio-chemestry. Clin Genet 1978; 14: 373394Google Scholar
Egeland, JAHostertter, AMAmish, Study IAffective disor-ders among the Amish, 19761980. Am J Psychiatry 1983; 140: 5661Google Scholar
Freeman, HAlpert, MPrevalence of schizophrenia in an urban population. Br J Psychiatry 1986; 149: 603611CrossRefGoogle Scholar
Gorwood, PLeboyer, MJay, MPayan, CFeingold, JGender and age at onset in schizophrenia: impact of family history. Am J Psychiatry 1995; 152: 208212Google ScholarPubMed
Gorwood, PLeboyer, MFallisard, BJay, MRouillon, FFeingold, JAnticipation in Schizophrenia: new lights on a controversial problem. Am J Psychiatry 1996; 153: 11731177Google ScholarPubMed
Gottesman, IIShields, Jeds. Schizophrenia, The Epigenetic Puzzle Cambridge: University Press, 1982 1635Google Scholar
Jablensky, ASartorious, NCulture and schizophrenia. Psychol Med 1975; 5: 113124CrossRefGoogle Scholar
Kato, MPsychiatric epidemiological surveys in JapanCaudill, WLin, TY eds. Mental Health Research in Asia and the Pacific Honolulu: East-West Center Press, 1969Google Scholar
Leboyer, MFilteau, MJJay, M, et al.Clinical subtypes and age at onset in schizophrenic siblings Psychiatry Res 1992; 41: 107114CrossRefGoogle ScholarPubMed
Leff, JPsychiatry Around the Globe: A Transcultural View New York: Marcel Dekker, 1981Google Scholar
Murphy, HBMRaman, ACThe chronicity of schizophrenia in indigenous tropical peoples Br J Psychiatry 118 1971 489497CrossRefGoogle ScholarPubMed
Torrey, FSchizophrenia and Civilization New York: Jason Aronson, 1980Google Scholar
Torrey, FPrevalence studies in Schizophrenia. Br J Psychiatry 1987; 150: 598608CrossRefGoogle Scholar
Torrey, FMcGuire, MO'Hare, AWalsh, DSpellman, MEnde-mic psychosis in Western Ireland. Am J Psychiatry 1984; 141: 966969Google ScholarPubMed
Vogel, FMotulsky, AGHuman Genetics. Problems and Approaches In: Vogel, FMotulsky, AG eds. Population genetics: consanguinity, genetic drift Berlin: Springer-Verlag, 1997 549582Google Scholar
Wing, LWing, JHailey, ABahn, Asmith, HThe use of psy-chiatric services in three urban areas: an international case register study. Soc Psychiatry 1967; 2: 158167CrossRefGoogle Scholar
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