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Organic affective disorder due to meningioma, case report

Published online by Cambridge University Press:  19 July 2023

M. Garcia-Moreno*
Affiliation:
HOSPITAL UNIVERSITARIO PUERTA DE HIERRO MAJADAHONDA
A. de Cós Milas
Affiliation:
HOSPITAL UNIVERSITARIO DE MÓSTOLES, MADRID, Spain
L. Beatobe Carreño
Affiliation:
HOSPITAL UNIVERSITARIO DE MÓSTOLES, MADRID, Spain
P. del Sol Calderón
Affiliation:
HOSPITAL UNIVERSITARIO PUERTA DE HIERRO MAJADAHONDA
Á. Izquierdo de la Puente
Affiliation:
HOSPITAL UNIVERSITARIO PUERTA DE HIERRO MAJADAHONDA
*
*Corresponding author.

Abstract

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Introduction

Brain tumors can be associated with psychiatric symptoms in up to 50% of cases. The most frequent primary is meningioma and the clinic will depend on its location. Since surgical treatment does not always guarantee complete resolution of the condition, concomitant psychopharmacological treatment is usually recommended.

Objectives

To review about organic mania and its differential diagnosis.

Methods

We carry out a literature review about organic affective disorder accompanied by a clinical description of one patient with organic mania.

Results

A 50-year-old woman admitted due to psychotic symptoms. She had a diagnosis of frontal and parietal meningioma treated with surgical treatment 10 years ago. In this context she had a diagnosis of Organic Affective Disorder and 3 previous psychiatric admissions due to affective or psychotic symptoms. Current episode consisted in dysphoria, magalomanic ideation, delusional ideation of harm and mystical-religious content, high speech pressure and insomnia with little awareness of the disease. Cranial magnetic resonance showed postoperative right frontal changes and stability in parietal meningioma, with no significant differences compared to the previous study. Diagnosis of Organic Affective Disorder is maintained and reintroduced treatment with aripiprazole withdrawaled by the patient weeks before. Because of adverse effects and persistence of the symptoms described, it was changed to olanzapine with good response and tolerability. The behavior was progressively adapted with improvement of the dysphoria and without psychotic symptoms at discharge.

Conclusions

Affective symptons due to organic disorders such as brain tumors can be treated surgically and with psychopharmacological treatment.

Disclosure of Interest

None Declared

Type
Abstract
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2023. Published by Cambridge University Press on behalf of the European Psychiatric Association
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