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P01-51-Impulsivity and decision making measured in cocaine addicts in France

Published online by Cambridge University Press:  16 April 2020

X. He ,
V. Bloch ,
G. Brousse ,
F. Vorspan  and
J.-P. Lépine
X. He
Affiliation:
Pôle Addictologie-Toxicologie-Psychiatrie, Hopital Fernand Widal, AP-HP, Paris, France Neuropsychopharmacologie des Addictions, INSERM U705 CNRS UMR 8206 Pres Sorbonne Paris Cite, Paris, France
V. Bloch
Affiliation:
Pôle Addictologie-Toxicologie-Psychiatrie, Hopital Fernand Widal, AP-HP, Paris, France Neuropsychopharmacologie des Addictions, INSERM U705 CNRS UMR 8206 Pres Sorbonne Paris Cite, Paris, France
G. Brousse
Affiliation:
Neuropsychopharmacologie des Addictions, INSERM U705 CNRS UMR 8206 Pres Sorbonne Paris Cite, Paris, France
F. Vorspan
Affiliation:
Pôle Addictologie-Toxicologie-Psychiatrie, Hopital Fernand Widal, AP-HP, Paris, France Neuropsychopharmacologie des Addictions, INSERM U705 CNRS UMR 8206 Pres Sorbonne Paris Cite, Paris, France
J.-P. Lépine
Affiliation:
Pôle Addictologie-Toxicologie-Psychiatrie, Hopital Fernand Widal, AP-HP, Paris, France Neuropsychopharmacologie des Addictions, INSERM U705 CNRS UMR 8206 Pres Sorbonne Paris Cite, Paris, France

Abstract

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Introduction

Impulsivity and decision making are impaired in cocaine addicts. However, most studies were performed in the USA.

Objectives

To assess impulsivity and decision making in a sample of French cocaine addicts.

Methods
Subjects

40 current cocaine addicts and 21 control subjects with no history of drug abuse were compared using the Barratt Impulsiveness Scale (BIS) and Iowa Gambling Task (IGT). Subjects from the cocaine addicted group were evaluated for cocaine craving with the Obessive Compulsive Cocaine Scale (OCCS), and for their pattern of use. Statistical analysis: The mean scores of impulsivity and decision making were compared in the two groups (Mann-Whitney U test). In the group of 40 cocaine addicts, clinical factors that could be associated with high impulsivity and poor decision making scores were tested (Spearman’ s rho, Chi-square and Mann-Whitney U tests).

Result

Compared to controls, cocaine addicts had a higher impulsivity score (BIS: 72 ± 11 vs 57 ± 8, U = 138, p < .001) and had more disadvantageous choices on the decision making test (IGT) (advantageous minus disadvantageous choices -4 ± 19 vs 24 ± 35, U = 234, p = .005). There was a significant correlation between high impulsivity scores on the BIS and high cocaine craving as well as heavy cocaine use (more than 4 times a week). No correlation was found between poor decision making and high craving or frequent cocaine use.

Discussion

The discrepancy between impulsivity and poor decision making in cocaine addicts is discussed.

Type
Research Article
Information
European Psychiatry , Volume 26 , Issue S2: Abstracts of the 19th European Congress of Psychiatry , March 2011 , pp. 51
Copyright
Copyright © European Psychiatric Association 2011
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