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P02-132 - Evaluation of Psychological Impact of Facial Lipoatrophy in HIV: the “Assessment of Face & Body Change and Distress” Questionnaire

Published online by Cambridge University Press:  17 April 2020

M. Ferrara
Affiliation:
Department of Neuroscience, TCR, University of Modena and Reggio Emilia, Modena, Italy
R. Murri
Affiliation:
Catholic University of Sacred Heart of Rome, Rome, Italy
E. Bertaccini
Affiliation:
Department of Medicine and Medical Specialties, Infectious Diseases Clinic, University of Modena and Reggio Emilia, Modena, Italy
G. Orlando
Affiliation:
Department of Medicine and Medical Specialties, Infectious Diseases Clinic, University of Modena and Reggio Emilia, Modena, Italy
M. Vandelli
Affiliation:
Department of Medicine and Medical Specialties, Infectious Diseases Clinic, University of Modena and Reggio Emilia, Modena, Italy
M. De Paola
Affiliation:
Department of Medicine and Medical Specialties, Infectious Diseases Clinic, University of Modena and Reggio Emilia, Modena, Italy
R. Bucciardini
Affiliation:
Dipartimento del Farmaco, Istituto Superiore di Sanità, Rome, Italy
M. Rigatelli
Affiliation:
Department of Neuroscience, TCR, University of Modena and Reggio Emilia, Modena, Italy
R. Esposito
Affiliation:
Department of Medicine and Medical Specialties, Infectious Diseases Clinic, University of Modena and Reggio Emilia, Modena, Italy
G. Guaraldi
Affiliation:
Department of Medicine and Medical Specialties, Infectious Diseases Clinic, University of Modena and Reggio Emilia, Modena, Italy
S. Ferrari
Affiliation:
Department of Neuroscience, TCR, University of Modena and Reggio Emilia, Modena, Italy

Abstract

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Objectives

To construct and test the validity of a new psychometric questionnaire to assess psychological impact of facial lipoatrophy (ABCD-F), that is the most stigmatizing feature of HIV-related lipodystrophy.

Methods

  • Construction: The development went through Focus groups and Content Validity, Item reduction and Exploratory Factor Analysis.

  • Validation: ABCD-F questionnaire was administered together with ABCD and MOS HIV questionnaires. The Cronbach's Alfa was used to test internal consistency, while convergent validity and divergent validity were analyzed by the correlations with MOS, ABCD items and BMI and CD4 counts respectively.

Results

42 HIV+ people participated to focus groups. In the EFA the 17 Items were aggregated around psychological distress and role functioning domains.

ABCD-F showed high internal consistency (Chronbach's alpha = 0.95). Both convergent and divergent validity were confirmed. ABCD-F scores were highly correlated to Physical Health Summary (B 0.59; 95% [CI] 0.35; 0.84; p< 0.0001), Mental Health Summary (B-1.54; 95% [CI] 1.15; 1.93; p< 0.0001), and weakly correlated to CD4 count (B-0.02; 95% [CI] -0.01; 0.06; p=0.54) and HIV viral load (B-0.004; 95% [CI] -2.69; 2.69; p=1.00).

Conclusions

ABCD-F is a valid and reliable questionnaire to assess psychological impact of facial lipoatrophy (FLA).

ABCD-F may result as a useful tool both in clinical and research settings: it's able to identify people experiencing greater psychological impact due to FLA. It may become an objective instrument to evaluate priority and efficacy of plastic surgery to treat lipodystrophy. In research setting may be used to compare different populations or different treatments of FLA.

Type
Methodology / Assessment methods / Rating scales
Copyright
Copyright © European Psychiatric Association 2010
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