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Principal-component analysis of PANSS and SANS - SAPS global ratings in schizophrenic patients

Published online by Cambridge University Press:  16 April 2020

S Dollfus ,
M Petit ,
P Lesieur  and
JF Menard
S Dollfus
Affiliation:
Department of Psychiatry, University of Rouen, CHS du Rouvray, Sotteville-les-Rouen, 76301
M Petit
Affiliation:
Department of Psychiatry, University of Rouen, CHS du Rouvray, Sotteville-les-Rouen, 76301
P Lesieur
Affiliation:
Department of Information and Research, CHS du Rouvray, Sotteville-les-Rouen, 76301
JF Menard
Affiliation:
Department of Biophysics, University of Rouen, Hospital Charles Nicolle, Rouen, France
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Summary

The aim of this study was to test whether a positive and a negative component could be found in broadly defined schizophrenic patients. Therefore, 70 patients either in an exacerbated or in a stabilized phase were selected according to the criteria of at least 1 of the 4 following diagnostic systems: DSM III-R, Schneider, Carpenter, Langfeldt; principal component analyses (PCA) were carried out with the 9 global ratings of the Scales for Assessment of Negative and Positive Symptoms (SANS and SAPS) and with the Positive and Negative Syndrome Scale (PANSS). The PCA of the SANS-SAPS global ratings yielded a 3-factor solution explaining 72.14% of the total variance, depicting a negative, a positive and a disorganization component. The PCA of the PANSS provided a 5-factor solution with a total explained variance of 55.98%. The first 3 factors were similar to those of the SANS-SAPS global rating analysis. The results showed that the positive and negative components described in a homogeneous schizophrenic population could be replicated in a larger and more heterogeneous group of schizophrenic patients. The question regarding the sufficiency of the positive-negative dichotomy was strengthened by the presence of a third disorganization component which explained as much of the variance as the positive component.

Keywords

schizophrenianegative symptomspositive symptomsdisorganizationscalesprincipal component analysis (PCA)
Type
Original article
Information
European Psychiatry , Volume 6 , Issue 5 , 1991 , pp. 251 - 259
Copyright
Copyright © Elsevier, Paris 1991

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References

Andreasen, NC (1982) Negative symptoms in schizophrenia. Arch Gen Psychiatry 39, 784–788CrossRefGoogle Scholar
Andreasen, NCOlsen, S (1982) Negative vs positive schizophrenia. Arch Gen Psychiatry 39, 789–794CrossRefGoogle Scholar
Andreasen, NC (1983) Comprehensive Assessment of Symptoms and History (CASH) The University of Iowa College of Medicine, Iowa City, IAGoogle Scholar
NC, AndreasenGrove, WM (1986) Evaluation of positive and negative symptoms in schizophrenia. Psychiatry & Psychobiol (I) 2, 108–121Google Scholar
Andreasen, NC (1987) The concept of negative symptoms: definition, specificity, and significance. Psychiatry & Psychobiol (II) 4, 240–251Google Scholar
Andreasen, NC (1989) The scale for the assessment of negative symptoms (SANS): conceptual and theoretical foundations. Br J Psychiatry 155 (suppl 7), 49, 58CrossRefGoogle Scholar
Arndt, SAlliger, RJAndreasen, NC (1991) The distinction of positive and negative symptoms. The failure of a two-dimensional model. Br J Psychiatry 158, 317–322CrossRefGoogle ScholarPubMed
Asberg, MPerris, CSchalling, DSedwall, G (1978) The CPRS: development and applications of a psychiatric rating scale. Acta Psychiatr Scand (Suppl 271), 1–69Google Scholar
Bilder, RMMurkherjee, SRieder, ROPandurangi, AK (1985) Symptomatic and neuropsychological components of defect states. Schizophr Bull 3, 409–419CrossRefGoogle Scholar
Bleuler, E (1911) Dementia Praecox or the Group of Schizophrenias. (Zinkin, J transl) International Universities Press, 1950, New YorkGoogle Scholar
De Bonis, MBoek, PLebeaux, MO (1987) Methodological problems in subtyping schizophrenics: correlations versus hierarchical relationships. Psychiatry & Psychobiol (II) 3, 174–187Google Scholar
Boyer, PLecrubier, Y (1987) Fiche descriptive et traduction francaise de la SAPS. Psychiatry & Psychobiol (11) 6, 425–437Google Scholar
Carpenter, WStephens, JHBartko, JJ (1973) Flexible system for diagnosis of schizophrenia: report from the WHO international pilot study of schizophrenia. Science 182, 1275CrossRefGoogle ScholarPubMed
Cornblatt, BALenzenweger, MFDworkin, RHErlenmeyer-Kimling, L (1985) Positive and negative schizophrenia symptoms, attention, and information processing. Schizophr Bull 11, 397–408CrossRefGoogle ScholarPubMed
Crow, TJ (1980) Positive and negative schizophrenic symptoms and the role of dopamine. Br J Psychiatry 137, 379–386CrossRefGoogle ScholarPubMed
DMS III-R (1987) Diagnostic and Statistical Manual of Mental Disorders, 3rd Ed, Revised. American Psychiatric Association, Washington, DCGoogle Scholar
Endicott, JSpitzer, RLA (1978) The schedule for affective disorders and schizophrenia. Arch Gen Psychiatry 35, 837–844CrossRefGoogle Scholar
Endicott, JNee, JCohen, JFleiss, JLSimon, R (1986) Diagnosis of schizophrenia. Prediction of short-term outcome. Arch Gen Psychiatry 43, 13–19CrossRefGoogle ScholarPubMed
Gibbons, RDLewine, RRJDavis, JMSchooler, NRCole, JO (1985) An empirical test of a Kraepelinian vs a Bleurerian view of negative symptoms. Schizophr Bull 11, 3, 390–396CrossRefGoogle Scholar
Harris, RJ (1975) A Primer of Multivariate Statistics. Academic Press, NYGoogle Scholar
Hawk, ABCarpenter, WTStrauss, JS (1975) Diagnostic criteria and five-years outcome in schizophrenia. A report from the international pilot study of schizophrenia. Arch Gen Psychiatry 32, 343–347CrossRefGoogle ScholarPubMed
Helzer, JEBrogkington, IFKendell, RE (1981) Predictive validity of DSM III and Feighner definitions of schizophrenia. Arch Gen Psychiatry 38, 791–797CrossRefGoogle ScholarPubMed
lager, ACDarrell, GKWyatt, RJ (1985) A negative symptom rating scale. Psychiatry Res 16, 27–36Google Scholar
Kay, SROpler, LAFiszbein, A (1986a) Significance of positive and negative syndromes in chronic schizophrenia. Br J Psychiatry 149, 439–448CrossRefGoogle Scholar
Kay, SRFiszbein, ALindenmayer, JPOpler, LA (1986b) Positive and negative syndromes in schizophrenia as a function of chronicity. Acta Psychiatr Scand 74, 507–518CrossRefGoogle Scholar
Kay, SRFiszbein, AOpler, LA (1987) The Positive and Negative syndrome Scale (PANSS) for schizophrenia. Schizophr Bull (13) 2, 261–275CrossRefGoogle Scholar
Kay, SROpler, LALindenmayer, JP (1988) Reliability and validity of the positive and negative syndrome scale for schizophrenia. Psychiatry Res 23, 99–110CrossRefGoogle Scholar
Kay, SROpler, LALindenmayer, JP (1989) The positive and negative syndrome scale (PANSS): rationale and standardisation. Br J Psychiatry 155 (suppl 7), 59–65CrossRefGoogle Scholar
Kay, SRSingh, MM (1989) The positive-negative distinction in drug-free schizophrenic patients. Arch Gen Psychiatry 46, 711–721CrossRefGoogle ScholarPubMed
Kay, SR (1990) Significance of the positive-negative distinction in schizophrenia. Schizophr Bull (16) 4, 635–652CrossRefGoogle Scholar
Kay, SRSevy, S (1990) Pyramidical model of schizophrenia. Schizophr Bull (16) 3, 537–545CrossRefGoogle Scholar
Kulhara, PKota, SKJoseph, S (1986) Positive and negative subtypes of schizophrenia. Acta Psychiatr Scand 74, 353–359CrossRefGoogle ScholarPubMed
Kraepelin, E (1919) Dementia praecox and paraphrenia.In: Psychiatry (Barlcay, RMRobertson, GM transl) RE Krieger, NY8th ednGoogle Scholar
Langfeld, G (1960) Diagnosis and prognosis of schizophrenia. Proc R Soc Med 53, 1047–1052Google Scholar
Lecrubier, YBoyer, P (1987) Fiche descriptive et traduction francaise de la SANS. Psychiatry & Psychobiol (11) 6, 414–424Google Scholar
Lepine, JPPiron, JJChapatot, E (1989) Factor analysis of the PANSS in schizophrenia patients.In: Psychiatry Today: Accomplishments and Promises (Stefanis, CNSoldatos, CRRabavilas, AD eds) Excerpta Medica, AmsterdamGoogle Scholar
Lewine, RRJFogg, LMeltzer, HY (1983) Assessment of negative and positive symptoms in schizophrenia. Schizophr Bull (9) 3, 368–376CrossRefGoogle Scholar
Liddle, PF (1987) The symptoms of chronic schizophrenia. A reexamination of the nositive-negative dichotomy. Br J Psychiatry 151, 145–151CrossRefGoogle Scholar
Liddle, PFBarnes, TREMorris, DHaque, S (1989) Three syndromes in chronic schizophrenia. Br J Psychiatry 155 (suppl 7), 119–122CrossRefGoogle Scholar
Lindenmayer, JPKay, SROpler, L (1984) Positive and negative subtype in acute schizophrenia. Comp Psychiatry 25, 455–464CrossRefGoogle Scholar
Lindenmayer, JPKay, SRFriedman, C (1986) Negative and positive schizophrenic syndromes after the acute phase: a prospective follow-up. Comp Psychiatry (27) 4, 276–286CrossRefGoogle Scholar
Loor, MKlett, CJMc Nair, OMLasky, JJ (1962) Inpatient Multidimensional Psychiatric Scale (IMPS) Manual. Veterans Administration, Washington, DCGoogle Scholar
McGlashan, TH (1984) Testing four diagnostic systems for schizophrenia. Arch Gen Psychiatry 41, 141–144CrossRefGoogle Scholar
Moorey, SGreer, SWatson, MGorman, CRowden, LTunmore, RRoberston, BBliss, J (1991) The factor structure and factor stability of the hospital anxiety and depression scale in patients with cancer. Br J Psychiatry 158, 255–259CrossRefGoogle ScholarPubMed
Mortimer, AMMc Kenna, PJLund, CEet al (1989) Rating of negative symptoms using the HEN. Br J Psychiatry 155 (suppl 7), 89–92CrossRefGoogle Scholar
Mortimer, AMLund, CEMcKenna, PJ (1990) The positive-negative dichotomy in schizophrenia. Br J Psychiatry 157, 41–49CrossRefGoogle Scholar
Opler, LAKay, SRRosado, VLindenmayer, JP (1984) Positive and negative syndromes in chronic schizophrenic inpatients. J Nerv Ment Dis 172, 6, 317–325CrossRefGoogle ScholarPubMed
Overall, JEGorham, DR (1962) Brief Psychiatric Rating Scale. Psychol Rep 10, 799CrossRefGoogle Scholar
Owens, DGCJohnstone, EC (1990) The disabilities of chronic schizophrenia. Their nature and the factors contributing to their development. Br J Psychiatry 136, 384–395CrossRefGoogle Scholar
PCSM(1990) Programme Conversationnel de Statistiques Pour les Sciences et le Marketing, Version 5. Deltasolft, MeylanGoogle Scholar
Pull, CBPull, MCPichot, P (1991) Licet-S: une liste integree de criteres devaluation toxinomiques pour les psychoses non-affectives. J Psychiatr Biol Ther 1, 33–37Google Scholar
Reuchlin, M (1987) Precis de Statistique. PUF, Paris, 4th edn, 256 ppGoogle Scholar
Rosen, WGMohs, RCJohns, CASmall, NSKendler, KSHorvath, TBDavis, KL (1984) Positive and negative symptoms in schizophrenia. Psychiatry Res 13, 277–284CrossRefGoogle Scholar
Schneider, K (1959) Clinical Psychopathology. Grune and Stratton, NYGoogle Scholar
Singh, MMKay, SR (1975) A comparative study of haloperidol and chlorpromazine in terms of clinical effects and therapeutic reversal with benztropine in schizophrenia: theoretical implications for potency differences among neuroleptics. Psychopharmacologia 43, 103–113CrossRefGoogle ScholarPubMed
Spohn, HECoyne, LLarson, JMittleman, FSpray, JHayes, K (1986) Episodic and residual thought pathology in chronic schizophrenics: effect of neuroleptics. Schizophr Bull (12) 3, 394–407CrossRefGoogle Scholar
Stephens, JHAstrup, CCarpenter, WTShaffer, JWGoldberg, J (1982) A comparison of nine systems to diagnose schizophrenia. Psychiatry Res 6, 127–143CrossRefGoogle Scholar
Strauss, JSCarpenter, WTBartko, JJ (1974) The diagnosis and understanding of schizophrenia. Part III. Speculations on the processes that underlie schizophrenic symptoms and signs. Schizophr Bull 11, 61–69CrossRefGoogle Scholar
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