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Risks factors for cocaine-induced psychotic disorder

Published online by Cambridge University Press:  16 April 2020

C. Roncero
Affiliation:
Outpatient Drug Clinic, Psychiatry Department, Hospital Universitarío Vall Hebron, Barcelona, Spain Psychiatric Department, Universidad Autónoma de Barcelona, Barcelona, Spain
M. Comin
Affiliation:
Outpatient Drug Clinic, Psychiatry Department, Hospital Universitarío Vall Hebron, Barcelona, Spain
C. Daigre
Affiliation:
Outpatient Drug Clinic, Psychiatry Department, Hospital Universitarío Vall Hebron, Barcelona, Spain
L. Grau-López
Affiliation:
Outpatient Drug Clinic, Psychiatry Department, Hospital Universitarío Vall Hebron, Barcelona, Spain
N. Martínez-Luna
Affiliation:
Outpatient Drug Clinic, Psychiatry Department, Hospital Universitarío Vall Hebron, Barcelona, Spain
F. Eiroa-Orosa
Affiliation:
Psychiatry Department, Hospital Universitarío Vall Hebron, Barcelona, Spain
L. Miquel
Affiliation:
Outpatient Drug Clinic, Psychiatry Department, Hospital Universitarío Vall Hebron, Barcelona, Spain
E. Castrillo
Affiliation:
Outpatient Drug Clinic, Psychiatry Department, Hospital Universitarío Vall Hebron, Barcelona, Spain
M. Torrens
Affiliation:
Drug Unit, Psychiatry Department, Hospital del Mar, Barcelona, Spain Psychiatry Department, Universidad Autónoma de Barcelona, Barcelona, Spain
M. Casas
Affiliation:
Psychiatric Department, Universidad Autónoma de Barcelona, Barcelona, Spain Psychiatry Department, Hospital Universitarío Vall Hebron, Barcelona, Spain

Abstract

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Introduction

Chronic consumption of cocaine can induce transient psychotic symptoms, expressed as paranoia or hallucinations. The term cocaine induced psychosis (CIP) has been used to describe this syndrome. Cocaine Induce Psichotic Disorder (CIPD) have been used to describe a full psychotic state. CIP and CIPD prevalences are not well described.

Objectives

To evaluate risk factors for CIPD, in cocaine-dependents according to DSM-IV criteria.

Methods

We evaluated 150 patients (mean age 34 y.o, 81.8% men) of which 143 were included, using The PRISM (Psychiatric Research for Substance and Mental Disorders) interview. Exclusion criteria were: psychotic disorder or bipolar type I disorder, intoxication at interview, severe somatic disease at interview and language barrier. We compared three groups: group I: without any psychotic symptoms (33,33%); group II: with any psychotic symptoms (28,57%) and group III: with CIPD (38,77%).

Results

Differences were found in Patients of Group III in the Age at onset of addiction p < .0001*, past history of imprisonment p < 0,01, Alcohol Use disorders p = .006, Cannabis use disorders P < .0001* and Hallucinogens use disorders p < 0,001.All remaining after Bonferroni corrections.

Conclusions

CIPD is common in this population (approximately 40%). Risk factor for suffering CIPD were described, in Cocaine-dependents. Finally, professionals who work with cocaine-dependents patients should incorporate these considerations into an integral approach.

Type
P01-96
Copyright
Copyright © European Psychiatric Association 2011
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