Affecting 7–10% of pregnancies, pre-eclampsia is, in fact, the most common glomerular disease worldwide. It remains a leading cause of fetal growth restriction, premature birth, as well as infant and maternal morbidity and mortality. Epidemiological studies have identified numerous risk factors for the development of pre-eclampsia including a positive family history, race, nulliparity, advanced maternal age and the presence of pre-existing co morbidities such as kidney disease, hypertension or diabetes mellitus. The incidence of pre-eclampsia has increased by an alarming 40% over the past decade, likely due to the number of women delaying pregnancy and/or becoming pregnant despite the presence of other comorbid conditions.