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Inactivation of Candida auris and Candida albicans by ultraviolet-C

Published online by Cambridge University Press:  21 May 2021

William A. Rutala*
Affiliation:
Division of Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill, North Carolina
Hajime Kanamori
Affiliation:
Division of Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill, North Carolina Department of Infectious Diseases, Internal Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
Maria F. Gergen
Affiliation:
Department of Hospital Epidemiology, University of North Carolina Medical Center, Chapel Hill, North Carolina
Emily E. Sickbert-Bennett
Affiliation:
Division of Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill, North Carolina Department of Hospital Epidemiology, University of North Carolina Medical Center, Chapel Hill, North Carolina
David J. Weber
Affiliation:
Division of Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill, North Carolina Department of Hospital Epidemiology, University of North Carolina Medical Center, Chapel Hill, North Carolina
*
Author for correspondence: William A. Rutala, E-mail: brutala@med.unc.edu

Abstract

We evaluated the ability of an ultraviolet-C (UV-C) room decontamination device to kill Candida auris and C. albicans. With an organic challenge (fetal calf serum), the UV-C device demonstrated the following log10 reductions for C. auris of 4.57 and for C. albicans of 5.26 with direct line of sight, and log10 reductions for C. auris of 2.41 and for C. ablicans of 3.96 with indirect line of sight.

Type
Concise Communication
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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References

Vallabhaneni, S, Kallen, A, Tsay, S, et al. Investigation of the first seven reported cases of Candida auris, a globally emerging invasive, multidrug-resistant fungus-United States, May 2013–August 2016. Morb Mortal Wkly Rep 2016;65:12341237.CrossRefGoogle Scholar
Schelenz, S, Hagen, F, Rhodes, JL, et al. First hospital outbreak of the globally emerging Candida auris in a European hospital. Antimicrob Resist Infect Control 2016;5:35.CrossRefGoogle Scholar
Biswal, M, Rudramurthy, SM, Jain, N, et al. Controlling a possible outbreak of Candida auris infection: lessons learnt from multiple interventions. J Hosp Infect 2017;97:363370.CrossRefGoogle ScholarPubMed
Cadnum, JC, Shaikh, AA, Piedrahita, CT, et al. Effectiveness of disinfectants against Candida auris and other Candida species. Infect Control Hosp Epidemiol 2017;38:12401243.CrossRefGoogle ScholarPubMed
Rutala, WA, Kanamori, K, Gergen, MF, Sickbert-Bennett, EE, Weber, DJ. Susceptibility of Candida auris and Candida albicans to 21 germicides used in healthcare facilities. Infect Control Hosp Epidemiol 2019;40:380382.CrossRefGoogle ScholarPubMed
Piedrahita, CT, Cadnum, JC, Jencson, AL, Shaikh, AA, Ghannoum, MA, Donskey, CJ. Environmental surfaces in healthcare facilities are a potential source for transmission of Candida auris and other Candida species. Infect Control Hosp Epidemiol 2017;38:11071109.CrossRefGoogle ScholarPubMed
Cadnum, JL, Shaikh, AA, Piedrahita, CT, et al. Relative resistance of the emerging fungal pathogen Candida auris and other Candida species to killing by ultraviolet light. Infect Control Hosp Epidemiol 2018;39:9496.CrossRefGoogle ScholarPubMed
deGroot, T, Chowdhary, A, Meis, JF, Voss, A. Killing of Candida auris by UV-C: importance of exposure time and distance. Mycoses 2019;62:408412.CrossRefGoogle Scholar
Recommendations for infection prevention and control for Candida auris. Centers for Disease Control and Prevention website. https://www.cdc.gov/fungal/candida-auris/c-auris-infection-control.html. Accessed January 19, 2021.Google Scholar
Cadnum, JL, Tomas, ME, Sankar, T, et al. Effect of variation in test methods on performance of ultraviolet-C radiation room decontamination. Infect Control Hosp Epidemiol 2016;37:555560.CrossRefGoogle ScholarPubMed