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Molecular and epidemiologic investigation of a rhinovirus outbreak in a neonatal intensive care unit

Published online by Cambridge University Press:  05 December 2018

Kenza Rahmouni El Idrissi ,
Sandra Isabel ,
Julie Carbonneau ,
Martine Lafond ,
Caroline Quach ,
Chelsea Caya ,
Patricia S. Fontela ,
Marc Beltempo ,
Guy Boivin  and
Marie-Astrid Lefebvre
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Kenza Rahmouni El Idrissi
Affiliation:
Faculty of Medicine, McGill University, Montreal, Quebec, Canada
Sandra Isabel
Affiliation:
Department of Pediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada
Julie Carbonneau
Affiliation:
Infectious Diseases Research Centre, CHU Quebec and Laval University, Quebec City, Quebec, Canada
Martine Lafond
Affiliation:
Infection Prevention and Control, Montreal Children’s Hospital, McGill University Health Centre, Montreal, Quebec, Canada
Caroline Quach
Affiliation:
Department of Microbiology, Infectious Diseases & Immunology, University of Montreal, Quebec, Canada
Chelsea Caya
Affiliation:
Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada
Patricia S. Fontela
Affiliation:
Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada Department of Pediatrics, Montreal Children’s Hospital, McGill University Health Centre, Montreal, Quebec, Canada Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada
Marc Beltempo
Affiliation:
Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada Department of Pediatrics, Montreal Children’s Hospital, McGill University Health Centre, Montreal, Quebec, Canada
Guy Boivin
Affiliation:
Infectious Diseases Research Centre, CHU Quebec and Laval University, Quebec City, Quebec, Canada
Marie-Astrid Lefebvre
Affiliation:
Infection Prevention and Control, Montreal Children’s Hospital, McGill University Health Centre, Montreal, Quebec, Canada Department of Pediatrics, Montreal Children’s Hospital, McGill University Health Centre, Montreal, Quebec, Canada
Jesse Papenburg*
Affiliation:
Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada Department of Pediatrics, Montreal Children’s Hospital, McGill University Health Centre, Montreal, Quebec, Canada Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada
*
Author for correspondence: Jesse Papenburg MD, MSc, Montreal Children’s Hospital 1001 Décarie Blvd, Room E05 1905, Montreal, QC, H4A 3J1. E-mail: Jesse.papenburg@mcgill.ca
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Abstract

We performed a molecular and epidemiologic study of a healthcare-associated rhinovirus outbreak to better understand transmission in neonatal intensive care settings. Sequencing of the 7 outbreak strains revealed 4 distinct clades, indicating multiple sources. A single clade infected 3 patients in adjacent rooms, suggesting horizontal transmission. We observed 1 rhinovirus-associated death.

Type
Research Brief
Information
Infection Control & Hospital Epidemiology , Volume 40 , Issue 2 , February 2019 , pp. 245 - 247
Copyright
© 2018 by The Society for Healthcare Epidemiology of America. All rights reserved. 

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Footnotes

PREVIOUS PRESENTATION: These study results were presented during a poster session at the Pediatric Academic Societies Meeting on May 6, 2018, in Toronto, Canada.

Cite this article: Rahmouni El Idrissi K, Isabel S, Carbonneau J, Lafond M, Quach C, Caya C, Fontela PS, Beltempo M, Boivin G, Lefebvre M-A, Papenburg J. (2019) Molecular and epidemiologic investigation of a rhinovirus outbreak in a neonatal intensive care unit. Infection Control & Hospital Epidemiology 2019, 40, 245–247. doi: 10.1017/ice.2018.311

References

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