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Susceptibility of healthcare personnel with severe acute respiratory coronavirus virus 2 (SARS-CoV-2) hybrid immunity to XBB lineage reinfection

Published online by Cambridge University Press:  20 February 2024

Karissa A. Whiting Open the ORCID record for Karissa A. Whiting [Opens in a new window] ,
Rebecca Guest Open the ORCID record for Rebecca Guest [Opens in a new window] ,
Venkatraman E. Seshan  and
Mini Kamboj
Karissa A. Whiting*
Affiliation:
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York
Rebecca Guest
Affiliation:
Employee Health, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York
Venkatraman E. Seshan
Affiliation:
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York
Mini Kamboj
Affiliation:
Infectious Diseases, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York Infection Control, Memorial Sloan Kettering Cancer Center, New York, New York Department of Medicine, Joan and Sanford Weill Medical College of Cornell University, New York, New York
*
Corresponding author: Karissa A. Whiting; Email: whitingk@mskcc.org
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Abstract

Among 8,678 vaccinated healthcare personnel (HCP) with previous coronavirus disease 2019 (COVID-19), by August 28, 2023, 909 (10%) had an infection of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) omicron XBB variant. Reinfection risk was comparable irrespective of previous infection type except for the omicron BQ.1 variant. Bivalent vaccination had a protective effect. COVID-19 vaccines remain vital to protect HCP, including those with hybrid immunity.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 45 , Issue 6 , June 2024 , pp. 781 - 784
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Copyright
© The Author(s), 2024. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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