Hostname: page-component-848d4c4894-sjtt6 Total loading time: 0 Render date: 2024-06-15T04:53:57.752Z Has data issue: false hasContentIssue false

Sustained reductions in unnecessary antimicrobial administration and hospital Clostridioides difficile rates via stewardship in a nonacademic setting

Published online by Cambridge University Press:  17 December 2021

Neil Gaffin*
Affiliation:
The Valley Hospital, Ridgewood, New Jersey Ridgewood Infectious Disease Associates, Ridgewood, New Jersey
Brad Spellberg
Affiliation:
Los Angeles County and University of Southern California Medical Center, Los Angeles, California
*
Author for correspondence: Neil Gaffin, E-mail: ngaffin@gmail.com

Abstract

A large community hospital sought to reduce its burden of hospital-acquired Clostridioides difficile infection (CDI). We implemented an antimicrobial stewardship program (ASP), resulting in marked reductions in unnecessary antimicrobial use, CDI rates, antimicrobial acquisition costs, with preservation of gram-negative susceptibilities. ASP programs are effective in a community setting.

Type
Concise Communication
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Magill, SS, Edwards, JR, Beldavs, ZG, et al. Emerging infections program healthcare-associated infections and antimicrobial use prevalence survey team. Prevalence of antimicrobial use in US acute-care hospitals, May–September 2011. JAMA 2014;312:14381446.CrossRefGoogle ScholarPubMed
Brown, K, Valenta, K, Fisman, D, Simor, A, Daneman, N. Hospital ward antibiotic prescribing and the risks of Clostridium difficile infection. JAMA Intern Med 2015;175:626633.CrossRefGoogle ScholarPubMed
US National Action Plan for combating antibiotic-resistant bacteria. Centers for Disease Control and Prevention website. https://www.cdc.gov/drugresistance/us-activities/national-action-plan.html. Accessed December 6, 2021.Google Scholar
Pollack, LA, Srinivasan, A. Core elements of hospital antibiotic stewardship programs from the Centers for Disease Control and Prevention. Clin Infect Dis 2014;59 suppl 3:S97S100.CrossRefGoogle Scholar
Spivak, ES, Cosgrove, SE, Srinivasan, A. Measuring appropriate antimicrobial use: attempts at opening the black box. Clin Infect Dis 2016;63:16391644.Google ScholarPubMed
Spellberg, B, Rice, LB. Duration of antibiotic therapy: shorter is better. Ann Intern Med 2019;171:210211.CrossRefGoogle ScholarPubMed
National Healthcare Safety Network. Multidrug-resistant organism & Clostridioides difficile (MDRO/CDI) infection surveillance and LabID event reporting module. Centers for Disease Control and Prevention website. https://www.cdc.gov/nhsn/about-nhsn/index.html. Accessed December 6, 2021.Google Scholar
Carey, RG, Lloyd, RC. Measuring Quality Improvement in Healthcare. Milwaukee, WI: Milwaukee Quality Press; 2001.Google Scholar
Hospital compare program. Centers for Medicare & Medicaid Services website. https://www.cms.gov/Medicare/Quality-Initiatives-Patient-Assessment-Instruments/HospitalQualityInits/HospitalCompare. Accessed December 6, 2021.Google Scholar
Stenehjem, E, Hersh, AL, Buckel, WR, et al. Impact of implementing antibiotic stewardship programs in 15 small hospitals: a cluster-randomized intervention. Clin Infect Dis 2018;67:525532.CrossRefGoogle ScholarPubMed