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P107: Paranoid Ideation Without Psychosis Is Associated With Depression, Anxiety, and Suicide Attempts in General Population

Published online by Cambridge University Press:  02 February 2024

Kyoungae Kim
Affiliation:
Department of Psychiatry, Depression Center, Samsung Medical Center, Sungkyunkwan University School of Medicine
Eun Jin Na
Affiliation:
Department of Psychiatry, Depression Center, Samsung Medical Center, Sungkyunkwan University School of Medicine
Kwan Woo Choi
Affiliation:
Department of Psychiatry, Anam Hospital, Korea University College of Medicine
Jin Pyo Hong
Affiliation:
Department of Psychiatry, Depression Center, Samsung Medical Center, Sungkyunkwan University School of Medicine
Maeng Je Cho
Affiliation:
Department of Psychiatry, Seoul National University, College of Medicine, Seoul, South Korea
Maurizio Fava
Affiliation:
Depression Clinical and Research Program, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
David Mischoulon
Affiliation:
Depression Clinical and Research Program, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
Hong Jin Jeon
Affiliation:
Department of Psychiatry, Depression Center, Samsung Medical Center, Sungkyunkwan University School of Medicine Departments of Health Sciences and Technology, Medical Device Management and Research, and Clinical Research Design and Evaluation, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul, South Korea
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Abstract

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This study aimed to characterize the association between paranoid ideation without psychosis (PIP) and suicide attempts in a general population. A total of 12,532 adults were randomly selected as the study sample through one-person-per-household method. Subjects completed a face-to-face interview. Among 12,532 subjects, 471 (3.76%) met criteria for the PIP group. The PIP group was younger with more divorced/widowed/separated and lower income than the non-PIP group. The PIP group showed more than fivefold higher lifetime suicide attempt (LSA) rates and ninefold multiple attempt rates than the non-PIP group. Among PIP symptoms, “spouse was being unfaithful” showed the strongest association with LSA (adjusted odds ratio [AOR], 4.49; 95% confidence interval, 2.95-6.85). Major depressive disorder (MDD) in combination with PIP was associated with a higher risk of LSA (AOR, 15.39; 95% confidence interval, 9.63-24.59) compared with subjects without MDD or PIP. In conclusion, PIP, especially “doubting spouse,” was significantly associated with LSA. PIP in combination with comorbid MDD showed higher risk of LSA than subjects without PIP or MDD.

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© International Psychogeriatric Association 2024