Hostname: page-component-848d4c4894-75dct Total loading time: 0 Render date: 2024-05-18T11:35:08.930Z Has data issue: false hasContentIssue false

Validation of the General Practitioner Assessment of Cognition – Chinese version (GPCOG-C) in China

Published online by Cambridge University Press:  09 July 2013

Xia Li
Affiliation:
Department of Psychogeriatrics, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, and Alzheimer's Disease and Related Disorders Center, Shanghai Jiaotong University, Shanghai, China
Shifu Xiao*
Affiliation:
Department of Psychogeriatrics, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, and Alzheimer's Disease and Related Disorders Center, Shanghai Jiaotong University, Shanghai, China
Yuan Fang
Affiliation:
Department of Psychogeriatrics, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, and Alzheimer's Disease and Related Disorders Center, Shanghai Jiaotong University, Shanghai, China
Minjie Zhu
Affiliation:
Department of Psychogeriatrics, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, and Alzheimer's Disease and Related Disorders Center, Shanghai Jiaotong University, Shanghai, China
Tao Wang
Affiliation:
Department of Psychogeriatrics, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, and Alzheimer's Disease and Related Disorders Center, Shanghai Jiaotong University, Shanghai, China
Katrin Seeher
Affiliation:
Dementia Collaborative Research Centre, University of New South Wales, Sydney, Australia Academic Department for Old Age Psychiatry, Prince of Wales Hospital, Sydney, Australia Centre for Healthy Brain Ageing, University of New South Wales, Sydney, Australia
Henry Brodaty
Affiliation:
Dementia Collaborative Research Centre, University of New South Wales, Sydney, Australia Academic Department for Old Age Psychiatry, Prince of Wales Hospital, Sydney, Australia Centre for Healthy Brain Ageing, University of New South Wales, Sydney, Australia
*
Correspondence should be addressed to: Prof. Shifu Xiao, Department of Psychogeriatrics, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, and Alzheimer's Disease and Related Disorders Center, Shanghai Jiaotong University, The South Wanping Road 600, Shanghai, China. Phone: +86-21-34289888; Fax: +86-21-54259931. Email: xiaoshifu@msn.com.

Abstract

Background:

To assess the reliability, validity, and diagnostic utility of the Chinese version of General Practitioner Assessment of Cognition (GPCOG-C). The GPCOG, which is specifically designed for use in primary care to screen for cognitive impairment, consists of a patient section testing cognition, and an informant section asking about decline in cognitive and functional abilities.

Methods:

The English version of GPCOG was translated, back-translated, and subsequently revised to determine the final GPCOG-C. Our sample comprised 253 community-dwelling volunteers with memory concerns aged 50 years and over and 103 outpatients of a psychogeriatric clinic with memory complaints. Participants were assessed by one of the four general practitioners or six psychogeriatricians. The Mini-Mental State Examination (MMSE), the Hasegawa's Dementia Scale (HDS), and the GPCOG-C were compared against the DSM-IV-defined dementia diagnosis.

Results:

The internal consistency (Cronbach's α) was 0.68 for the GPCOG patient section. The test–retest was 0.98 for the GPCOG-C total. The sequential administration of both components of GPCOG-C had a sensitivity of 97% and a specificity of 89%, with a positive predictive value of 72% and a negative predictive value of 99%. Both the GPCOG-C total and sequential two-stage scoring methods performed at least well as the MMSE and HDS in detecting dementia. The administration time for the two-stage approach was 4.3 ± 2.4 min.

Conclusions:

The GPCOG-C is a valid, time efficient instrument for dementia screening in China.

Type
Research Article
Copyright
Copyright © International Psychogeriatric Association 2013 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Alagiakrishnan, K.et al. (2007). Simple cognitive testing (Mini-Cog) predicts in-hospital delirium in the elderly. Journal of the American Geriatrics Society, 55, 314316.CrossRefGoogle ScholarPubMed
Aranda-Abreu, G. E., Hernandez-Aguilar, M. E., Manzo, D. J., Garcia, H. L. and Herrera, R. M. (2011). Rehabilitating a brain with Alzheimer's: a proposal. Clinical Interventions in Aging, 6, 5359.CrossRefGoogle ScholarPubMed
Brodaty, H., Howarth, G. C., Mant, A. and Kurrle, S. E. (1994). General practice and dementia. A national survey of Australian GPs. Medical Journal of Australia, 160, 1014.CrossRefGoogle ScholarPubMed
Brodaty, H.et al. (2002). The GPCOG: a new screening test for dementia designed for general practice. Journal of the American Geriatrics Society, 50, 530534.CrossRefGoogle ScholarPubMed
Brodaty, H., Kemp, N. M. and Low, L. F. (2004). Characteristics of the GPCOG, a screening tool for cognitive impairment. International Journal of Geriatric Psychiatry, 19, 870874.CrossRefGoogle ScholarPubMed
Brodaty, H., Low, L. F., Gibson, L. and Burns, K. (2006). What is the best dementia screening instrument for general practitioners to use? American Journal of Geriatric Psychiatry, 14, 391400.CrossRefGoogle ScholarPubMed
Connolly, A., Gaehl, E., Martin, H., Morris, J. and Purandare, N. (2011). Underdiagnosis of dementia in primary care: variations in the observed prevalence and comparisons to the expected prevalence. Aging and Mental Health, 15, 978984.CrossRefGoogle Scholar
Flaherty, J. H.et al. (2007). China: the aging giant. Journal of the American Geriatrics Society, 55, 12951300.CrossRefGoogle ScholarPubMed
Folstein, M. F., Folstein, S. E. and McHugh, P. R. (1975). “Mini-mental state.” A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12, 189198.CrossRefGoogle ScholarPubMed
Hasegawa, K. (1979). The clinical assessment of age-related dementia (author's translation). Nihon Ronen Igakkai Zasshi, 16, 191198.CrossRefGoogle Scholar
Holsinger, T.et al. (2007) Does this patient have dementia? JAMA, 297, 23912404.CrossRefGoogle ScholarPubMed
Ken, K., Okuno, J., Fukasaku, T., Tomura, S. and Yanagi, H. (2010). Factors affecting burden of caregivers for the elderly of Han Chinese and the Korean minority living in a community in northeast China. Nihon Koshu Eisei Zasshi, 57, 816824.Google Scholar
Kim, K. W.et al. (2005). Diagnostic accuracy of mini-mental status examination and revised Hasegawa dementia scale for Alzheimer's Disease. Dementia and Geriatric Cognitive Disorders, 19, 324330.CrossRefGoogle ScholarPubMed
Kim, J. L.et al. (2011). Interactive influences of demographics on the Mini-Mental State Examination (MMSE) and the demographics-adjusted norms for MMSE in elderly Koreans. International Psychogeriatrics, 14, 19.Google Scholar
Malloy, P. F.et al. (1997). Cognitive screening instruments in neuropsychiatry: a report of the Committee on Research of the American Neuropsychiatric Association. The Journal of Neuropsychiatry and Clinical Neurosciences, 9, 189197.Google Scholar
Milne, A., Culverwell, A., Guss, R., Tuppen, J. and Whelton, R. (2008). Screening for dementia in primary care: a review of the use, efficacy and quality of measures. International Psychogeriatrics, 20, 911926.CrossRefGoogle ScholarPubMed
Mitchell, A. J. (2009). A meta-analysis of the accuracy of the Mini-Mental State Examination in the detection of dementia and mild cognitive impairment. Journal of Psychiatric Research, 43, 411431.CrossRefGoogle ScholarPubMed
Molnar, F. J., Patel, A., Marshall, S. C., Man-Son-Hing, M. and Wilson, K. G. (2006). Clinical utility of office-based cognitive predictors of fitness to drive in persons with dementia: a systematic review. Journal of the American Geriatrics Society, 54, 18091824.CrossRefGoogle ScholarPubMed
Pirani, A., Brodaty, H., Martini, E., Zaccherini, D., Neviani, F. and Neri, M. (2010). The validation of the Italian version of the GPCOG (GPCOG-It): a contribution to cross-national implementation of a screening test for dementia in general practice. International Psychogeriatrics, 22, 8290.CrossRefGoogle ScholarPubMed
Sousa, R. M.et al. (2009). Contribution of chronic diseases to disability in elderly people in countries with low and middle incomes: a 10/66 Dementia Research Group population-based survey. Lancet, 374, 18211830.CrossRefGoogle Scholar
Shanghai Civil Affairs Bureau. (2011). Statistics Information on Shanghai Aged Population and Aging Affairs Management in 2011. Available at http://www.shmzj.gov.cn/gb/shmzj/node8/node194/userobject1ai32031.html/; last accessed 31 March 2012 (in Chinese).Google Scholar
Thomas, P., Hazif-Thomas, C., Vieban, F., Faugeron, P., Peix, R. and Clement, J. P. (2006). The GPcog for detecting a population with a high risk of dementia. Psychologie & Neuropsychiatrie du Vieillissenent, 4, 6977 (in French).Google ScholarPubMed
Tsai, N. and Gao, Z. X. (1989). Validity of Hasegawa's dementia scale for screening dementia among aged Chinese. International Psychogeriatrics, 1, 145152.CrossRefGoogle ScholarPubMed
Valcour, V. G.et al. (2000). The detection of dementia in the primary care setting. Archives of Internal Medicine, 160, 29642968.CrossRefGoogle ScholarPubMed
Xiao, G.et al. (2010). There is a long way to go: a nationwide survey of professional training for mental health practitioners in China. Health Policy, 95, 7481.Google Scholar