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Respiratory viral infections during pregnancy: effects of SARS-CoV-2 and other related viruses over the offspring

Part of: DOHaD Covid-19 Collection

Published online by Cambridge University Press:  02 February 2021

Claudia Riedel ,
Juan Carlos Rivera ,
Gisela Canedo-Marroquín ,
Alexis M. Kalergis  and
Ma. Cecilia Opazo Open the ORCID record for Ma. Cecilia Opazo [Opens in a new window]
Claudia Riedel
Affiliation:
Departamento de Ciencias Biológicas, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago, Chile Millennium Institute of Immunology and Immunotherapy Departamento de Ciencias Biológicas, Facultad de Ciencias de la Vida, Andres Bello University, Santiago, Chile
Juan Carlos Rivera
Affiliation:
Departamento de Ciencias Biológicas, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago, Chile Millennium Institute of Immunology and Immunotherapy Departamento de Ciencias Biológicas, Facultad de Ciencias de la Vida, Andres Bello University, Santiago, Chile
Gisela Canedo-Marroquín
Affiliation:
Millennium Institute of Immunology and Immunotherapy, Departamento de Genética Molecular y Microbiología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile
Alexis M. Kalergis
Affiliation:
Millennium Institute of Immunology and Immunotherapy, Departamento de Genética Molecular y Microbiología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile Millennium Institute of Immunology and Immunotherapy, Departamento de Endocrinología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile
Ma. Cecilia Opazo*
Affiliation:
Departamento de Ciencias Biológicas, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago, Chile Millennium Institute of Immunology and Immunotherapy Departamento de Ciencias Biológicas, Facultad de Ciencias de la Vida, Andres Bello University, Santiago, Chile
*
Address for correspondence: Ma. Cecilia Opazo, República 330, 2do piso, Departamento de Ciencias Biológicas, Facultad de Ciencias de la Vida, Universidad Andrés Bello, Santiago, Chile. Email: maria.opazo@unab.cl; cecilia.opazo@gmail.com
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Abstract

Little is known about the consequences of viral infection for pregnant woman or for the fetus. This issue became important with the appearance of the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). The infection with SARS-CoV-2 causes a respiratory syndrome known as COVID-19. The fast spreading around the world and the fact that without a treatment or vaccine humans are completely exposed, converts emerging viral diseases in a significant risk for pregnant women and their infants. At this time, during SARS-CoV-2 pandemics pregnant women are not considered as a risk population and little is known about the effects of viral infections over the offspring although the amount of emerging evidence showing detrimental effects for the mother and the fetus. This issue highlights the importance to understand the effects of viral infections during pregnancy. In this work, we analyze the effects of viral infections, like SARS-CoV-2 and other related viruses during pregnancy over the mother and the consequences for the offspring.

Keywords

SARS-CoV-2pregnancyoffspring immune response
Type
Review
Information
Journal of Developmental Origins of Health and Disease , Volume 13 , Issue 1 , February 2022 , pp. 3 - 8
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Copyright
© The Author(s), 2021. Published by Cambridge University Press in association with International Society for Developmental Origins of Health and Disease

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