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Anemia and Spaceflight Associated Neuro-Ocular Syndrome (SANS)

Published online by Cambridge University Press:  31 July 2023

Ethan Waisberg*
Affiliation:
University College Dublin School of Medicine, Belfield, Dublin, Ireland
Joshua Ong
Affiliation:
Michigan Medicine, University of Michigan, Ann Arbor, Michigan USA
Mouayad Masalkhi
Affiliation:
University College Dublin School of Medicine, Belfield, Dublin, Ireland
Andrew G. Lee
Affiliation:
Center for Space Medicine, Baylor College of Medicine, Houston, Texas USA Department of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas USA Houston Methodist Research Institute, Houston Methodist Hospital, Houston, Texas USA Departments of Ophthalmology, Neurology, and Neurosurgery, Weill Cornell Medicine, New York, New York USA Department of Ophthalmology, University of Texas Medical Branch, Galveston, Texas USA University of Texas MD Anderson Cancer Center, Houston, Texas USA Texas A&M College of Medicine, Bryan, Texas USA Department of Ophthalmology, University of Iowa Hospitals and Clinics, Iowa City, Iowa USA
*
Correspondence: Ethan Waisberg University College Dublin School of Medicine Belfield, Dublin 4, Ireland E-mail: ethan.waisberg@ucdconnect.ie

Abstract

Spaceflight associated neuro-ocular syndrome (SANS) is a collection of distinct findings seen in some astronauts following prolonged spaceflight and is characterized by: optic disc edema, globe flattening, and choroidal folds. In this manuscript, we describe the potential mechanisms linking anemia and SANS. Future research aimed at understanding the relationship between these conditions may help to develop countermeasures and mitigation efforts for SANS.

Type
Article Commentary
Copyright
© The Author(s), 2023. Published by Cambridge University Press on behalf of the World Association for Disaster and Emergency Medicine

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