Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-848d4c4894-5nwft Total loading time: 0 Render date: 2024-06-02T12:28:35.059Z Has data issue: false hasContentIssue false

Chapter 8 - Optimizing Body Weight to Improve Reproductive Success

Published online by Cambridge University Press:  08 February 2018

By
Kelton Tremellen
Edited by
Gab Kovacs  and
Robert Norman
Gab Kovacs
Affiliation:
Monash University, Victoria
Robert Norman
Affiliation:
University of Adelaide
Get access

Summary

A summary is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Chapter
Information
How to Improve Preconception Health to Maximize IVF Success , pp. 66 - 75
Publisher: Cambridge University Press
Print publication year: 2018

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Jensen, M. D., Ryan, D. H., Apovian, C. M., et al., American College of Cardiology/American Heart Association Task Force on Practice Guidelines; Obesity Society. 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. Circulation 2014 Jun 24;129(25 Suppl 2):S102–138.Google Scholar
Bolúmar, F., Olsen, J., Rebagliato, M., et al. Body mass index and delayed conception: a European multicenter study on infertility and subfecundity. Am J Epidemiol 2000 Jun 1;151(11):1072–1079.Google Scholar
Rich-Edwards, J. W., Spiegelman, D., Garland, M., et al. Physical activity, body mass index, and ovulatory disorder infertility. Epidemiology 2002 Mar;13(2):184–190.Google Scholar
Ramlau-Hansen, C. H, Thulstrup, A. M., Nohr, E. A., et al. Subfecundity in overweight and obese couples. Hum Reprod 2007 Jun;22(6):1634–1637.CrossRefGoogle ScholarPubMed
Wise, L. A., Palmer, J. R., and Rosenberg, L. Body size and time-to-pregnancy in black women. Hum Reprod 2013 Oct;28(10):2856–2864.Google Scholar
Conway, G., Dewailly, D., Diamanti-Kandarakis, E., et al., ESE PCOS Special Interest Group. The polycystic ovary syndrome: a position statement from the European Society of Endocrinology. Eur J Endocrinol 2014 Oct;171(4):P1–29.CrossRefGoogle ScholarPubMed
Wu, L. L., Norman, R. J., and Robker, R. L. The impact of obesity on oocytes: evidence for lipotoxicity mechanisms. Reprod Fertil Dev 2011;24(1):29–34.CrossRefGoogle ScholarPubMed
Metwally, M., Cutting, R., Tipton, A., et al. Effect of increased body mass index on oocyte and embryo quality in IVF patients. Reprod Biomed Online 2007 Nov;15(5):532–538.Google Scholar
Leary, C., Leese, H. J., and Sturmey, R. G. Human embryos from overweight and obese women display phenotypic and metabolic abnormalities. Hum Reprod 2015 Jan;30(1):122–132.CrossRefGoogle ScholarPubMed
Bellver, J., Ayllón, Y., Ferrando, M., et al. Female obesity impairs in vitro fertilization outcome without affecting embryo quality. Fertil Steril 2010 Feb;93(2):447–454.Google Scholar
Goldman, K. N., Hodes-Wertz, B., McCulloh, DH, et al. Association of body mass index with embryonic aneuploidy. Fertil Steril 2015 Mar;103(3):744–748.Google Scholar
Provost, M. P., Acharya, K. S., Acharya, C. R., et al. Pregnancy outcomes decline with increasing body mass index: analysis of 239,127 fresh autologous in vitro fertilization cycles from the 2008–2010 Society for Assisted Reproductive Technology registry. Fertil Steril 2016 Mar;105(3):663–669.CrossRefGoogle Scholar
Tremellen, K., Pearce, K., and Zander-Fox, D. L. Increased miscarriage of euploid pregnancies in obese women undergoing cryopreserved embryo transfer. Reprod Biomed Online 2017 Jan;34(1):90–97. doi: 10.1016/j.rbmo.2016.09.011.CrossRefGoogle ScholarPubMed
Bellver, J., Pellicer, A., García-Velasco, J. A., et al. Obesity reduces uterine receptivity: clinical experience from 9,587 first cycles of ovum donation with normal weight donors. Fertil Steril 2013 Oct;100(4):1050–1058.CrossRefGoogle Scholar
Provost, M. P., Acharya, K. S., Acharya, C. R., et al. Pregnancy outcomes decline with increasing recipient body mass index: an analysis of 22,317 fresh donor/recipient cycles from the 2008–2010 Society for Assisted Reproductive Technology Clinic Outcome Reporting System registry. Fertil Steril 2016 Feb;105(2):364–368.CrossRefGoogle Scholar
Jungheim, E. S., Schon, S. B., Schulte, M. B., et al. IVF outcomes in obese donor oocyte recipients: a systematic review and meta-analysis. Hum Reprod 2013 Oct;28(10):2720–2727.Google Scholar
Metwally, M., Ong, K. J., Ledger, W. L., and Li, T. C. Does high body mass index increase the risk of miscarriage after spontaneous and assisted conception? A meta-analysis of the evidence. Fertil Steril 2008 Sep;90(3):714–726.CrossRefGoogle Scholar
Kroon, B., Harrison, K., Martin, N., et al. Miscarriage karyotype and its relationship with maternal body mass index, age, and mode of conception. Fertil Steril 2011 Apr;95(5):1827–1829.Google Scholar
Marchi, J., Berg, M., Dencker, A., et al. Risks associated with obesity in pregnancy, for the mother and baby: a systematic review of reviews. Obes Rev 2015 Aug;16(8):621–638.CrossRefGoogle Scholar
Lane, M., Zander-Fox, D. L., Robker, R. L., and McPherson, N. O. Peri-conception parental obesity, reproductive health, and transgenerational impacts. Trends Endocrinol Metab 2015 Feb;26(2):84–90.CrossRefGoogle ScholarPubMed
Homan, G. F., Davies, M., and Norman, R. The impact of lifestyle factors on reproductive performance in the general population and those undergoing infertility treatment: a review. Hum Reprod Update 2007 May–Jun;13(3):209–223.Google Scholar
Mutsaerts, M. A., van Oers, A. M., Groen, H., et al. Randomized trial of a lifestyle program in obese infertile women. N Engl J Med 2016 May 19;374(20):1942–1953.Google Scholar
Legro, R. S., Dodson, W. C., Kunselman, A. R., et al. Benefit of delayed fertility therapy with preconception weight loss over immediate therapy in obese women with PCOS. J Clin Endocrinol Metab 2016 Jul;101(7):2658–2666.Google Scholar
Moran, L., Tsagareli, V., Norman, R., and Noakes, M. Diet and IVF pilot study: short-term weight loss improves pregnancy rates in overweight/obese women undertaking IVF. Aust N Z J Obstet Gynaecol 2011 Oct;51(5):455–459.Google Scholar
Chavarro, J. E., Ehrlich, S., Colaci, D. S., et al. Body mass index and short-term weight change in relation to treatment outcomes in women undergoing assisted reproduction. Fertil Steril 2012 Jul;98(1):109–116.CrossRefGoogle ScholarPubMed
Apovian, C. M., Aronne, L. J., Bessesen, D. H., et al., Endocrine Society. Pharmacological management of obesity: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2015 Feb;100(2):342–362.Google Scholar
Tsagareli, V., Noakes, M., and Norman, R. J. Effect of a very-low-calorie diet on in vitro fertilization outcomes. Fertil Steril 2006 Jul;86(1):227–229.CrossRefGoogle ScholarPubMed
Gudzune, K. A., Bleich, S. N., and Clark, J. M. Efficacy of commercial weight-loss programs. Ann Intern Med 2015 Sep 1;163(5):399.Google Scholar
Kjaer, M. M. and Nilas, L. Pregnancy after bariatric surgery–a review of benefits and risks. Acta Obstet Gynecol Scand 2013 Mar;92(3):264–271.Google Scholar
Sermondade, N., Faure, C., Fezeu, L., et al. BMI in relation to sperm count: an updated systematic review and collaborative meta-analysis. Hum Reprod Update 2013 May–Jun;19(3):221–231.Google Scholar
Tunc, O., Bakos, H. W., and Tremellen, K. Impact of body mass index on seminal oxidative stress. Andrologia 2011 Apr;43(2):121–128.Google Scholar
Dupont, C., Faure, C., Sermondade, N., et al. Obesity leads to higher risk of sperm DNA damage in infertile patients. Asian J Androl 2013 Sep;15(5):622–625.CrossRefGoogle ScholarPubMed
Colaci, D. S., Afeiche, M., Gaskins, A. J., et al. Men’s body mass index in relation to embryo quality and clinical outcomes in couples undergoing in vitro fertilization. Fertil Steril 2012 Nov;98(5):1193–1199.e1.Google Scholar
Tremellen, K. Gut Endotoxin Leading to a Decline IN Gonadal function (GELDING) – a novel theory for the development of late onset hypogonadism in obese men. Basic Clin Androl 2016 Jun 22;26:7.CrossRefGoogle Scholar
Pinborg, A., Gaarslev, C., Hougaard, C. O., et al. Influence of female bodyweight on IVF outcome: a longitudinal multicentre cohort study of 487 infertile couples. Reprod Biomed Online 2011 Oct;23(4):490–499.Google Scholar
Pandey, S., Maheshwari, A., and Bhattacharya, S. Should access to fertility treatment be determined by female body mass index? Hum Reprod 2010 Apr;25(4):815–820.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×