14 results
416 MRI Findings in Preterm Infants Associated with Strabismus
- Part of
- Jacob I. Strelnikov, Rachel Lean, Christopher D. Smyser, Cynthia Rogers, Mae Gordon, John R. Pruett, Jr., Susan Culican, Savannah Seupaul, Alisha Dhallan, Margaret Reynolds
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- Journal:
- Journal of Clinical and Translational Science / Volume 8 / Issue s1 / April 2024
- Published online by Cambridge University Press:
- 03 April 2024, p. 124
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OBJECTIVES/GOALS: Prematurity and perinatal brain injury are known risk factors for strabismus. In this study, we sought to understand the link between neonatal neuroimaging measures in very preterm infants and the emergence of strabismus later in life. Study findings may inform if neonatal brain MRI could serve as a prognostic tool for this visual disorder. METHODS/STUDY POPULATION: This study draws from a longitudinal cohort of very preterm infants (VPT, < 30 weeks gestation, range 23 – 29 weeks) who underwent an MRI scan at 36 to 43 weeks postmenstrual age (PMA). Anatomic and diffusion MRI data were collected for each child . A subset of thirty-three patients in this cohort had records of an eye exam, which were reviewed for a history of strabismus. Patients with MRI scans demonstrating cystic periventricular leukomalacia or grade III/IV intraventricular hemorrhage were classified as having brain injury. Clinical variables with a known association to strabismus or diffusion metrics were included in a multivariable logistic regression model. Diffusion tractography metrics were screened for association with strabismus on univariable analysis prior to inclusion in the regression model. RESULTS/ANTICIPATED RESULTS: A total of 17/33 (51.5%) patients developed strabismus. A logistic regression model including gestational age, PMA at MRI, retinopathy of prematurity (ROP) stage, brain injury, and fractional anisotropy of the right optic radiation was significant at the .001 level according to the chi-square statistic. The model predicted 88% of responses correctly. Each decrease of 0.01 in the fractional anisotropy of the right optic radiation increased the odds of strabismus by a factor of 1.5 (95% CI 1.03 – 2.06; p = .03). Patients with brain injury had 15.8 times higher odds of strabismus (95% CI 1.1 – 216.5; p = .04). Gestational age (OR 1.7; 95% CI 0.9 – 3.3; p = .1) and stage of ROP (OR 0.6; 95% CI 0.2 – 2.0; p = .4) were not significant predictors of strabismus in the multivariable model. DISCUSSION/SIGNIFICANCE: Our findings suggest that strabismus in VPT patients may be related to specific changes in brain structure in the neonatal period. The identified association between neonatal optic radiation microstructure and strabismus supports the possibility of using brain MRI in very preterm infants to prognosticate visual and ocular morbidity.
On more than two decades of Celestial Reference Frame VLBI observations in the deep south: IVS-CRDS (1995–2021)
- S. Weston, A. de Witt, Hana Krásná, Karine Le Bail, Sara Hardin, David Gordon, Shu Fengchun, Alan Fey, Matthias Schartner, Sayan Basu, Oleg Titov, Dirk Behrend, Christopher S. Jacobs, Warren Hankey, Federico Salguero, John E. Reynolds
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- Journal:
- Publications of the Astronomical Society of Australia / Volume 40 / 2023
- Published online by Cambridge University Press:
- 20 June 2023, e041
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The International VLBI Service for Geodesy and Astrometry (IVS) regularly provides high-quality data to produce Earth Orientation Parameters (EOP), and for the maintenance and realisation of the International Terrestrial and Celestial Reference Frames, ITRF and ICRF. The first iteration of the celestial reference frame (CRF) at radio wavelengths, the ICRF1, was adopted by the International Astronomical Union (IAU) in 1997 to replace the FK5 optical frame. Soon after, the IVS began official operations and in 2009 there was a significant increase in data sufficient to warrant a second iteration of the CRF, ICRF2. The most recent ICRF3, was adopted by the IAU in 2018. However, due to the geographic distribution of observing stations being concentrated in the Northern hemisphere, CRFs are generally weaker in the South due to there being fewer Southern Hemisphere observations. To increase the Southern Hemisphere observations, and the density, precision of the sources, a series of deep South observing sessions was initiated in 1995. This initiative in 2004 became the IVS Celestial Reference Frame Deep South (IVS-CRDS) observing programme. This paper covers the evolution of the CRDS observing programme for the period 1995–2021, details the data products and results, and concludes with a summary of upcoming improvements to this ongoing project.
Negative emotionality as a candidate mediating mechanism linking prenatal maternal mood problems and offspring internalizing behaviour
- Cathryn Gordon Green, Eszter Szekely, Vanessa Babineau, Alexia Jolicoeur-Martineau, Andrée-Anne Bouvette-Turcot, Klaus Minde, Roberto Sassi, Leslie Atkinson, James L. Kennedy, Meir Steiner, John Lydon, Helene Gaudreau, Jacob A. Burack, Catherine Herba, Marie-Helene Pennestri, Robert Levitan, Michael J. Meaney, Ashley Wazana
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- Journal:
- Development and Psychopathology / Volume 35 / Issue 2 / May 2023
- Published online by Cambridge University Press:
- 20 April 2022, pp. 604-618
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Negative emotionality (NE) was evaluated as a candidate mechanism linking prenatal maternal affective symptoms and offspring internalizing problems during the preschool/early school age period. The participants were 335 mother–infant dyads from the Maternal Adversity, Vulnerability and Neurodevelopment project. A Confirmatory Bifactor Analysis (CFA) based on self-report measures of prenatal depression and pregnancy-specific anxiety generated a general factor representing overlapping symptoms of prenatal maternal psychopathology and four distinct symptom factors representing pregnancy-specific anxiety, negative affect, anhedonia and somatization. NE was rated by the mother at 18 and 36 months. CFA based on measures of father, mother, child-rated measures and a semistructured interview generated a general internalizing factor representing overlapping symptoms of child internalizing psychopathology accounting for the unique contribution of each informant. Path analyses revealed significant relationships among the general maternal affective psychopathology, the pregnancy- specific anxiety, and the child internalizing factors. Child NE mediated only the relationship between pregnancy-specific anxiety and the child internalizing factors. We highlighted the conditions in which prenatal maternal affective symptoms predicts child internalizing problems emerging early in development, including consideration of different mechanistic pathways for different maternal prenatal symptom presentations and child temperament.
Tributes to Hubert Foss
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- By Herbert Howells, Royal Hotel, Bristol, Gordon Jacob, Pine Cottage, Brockenhurst, Hants., Dora Powell, Poels, East Grinstead, Sussex, Percy Scholes, Rutland House, 41 Davenant Road, Oxford, Ralph Vaughan Williams, The White Gates, Dorking, Michael Ayrton, Bradfields, Toppesfield, Essex, William Walton, Lowndes Cottage, Lowndes Place, London SW1, Arthur Bliss, 15 Cottesmore Gardens, W8, Edward Dent, 17 Cromwell Place, SW7, John Gardner, 4 South Close, Morden, Surrey, Roger Quilter, none
- Edited by Stephen Lloyd, Diana Sparkes, Brian Sparkes
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- Book:
- Music in Their Time: The Memoirs and Letters of Dora and Hubert Foss
- Published by:
- Boydell & Brewer
- Published online:
- 25 March 2020
- Print publication:
- 18 October 2019, pp 239-254
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Summary
From Herbert Howells
261. 28th May 1953 Herbert Howells to DMF
Royal Hotel, Bristol
My dear Dora:
Here in Bristol this morning I have read with great concern and very real regret of Hubert's death, and it has come not only with disturbing unexpectedness but with added poignancy in this week of general colour and happiness. I send you and your son and daughter the very genuine sympathy of a fellowmusician to whom Hubert shewed unfailing and most heartening kindness and encouragement right through the years.
My last news of him had been so reassuring. He was, I know, destined for new and important editorial work in a post he w[oul]d have filled brilliantly: and he must have been looking forward to it keenly.
We will all be so sorry it was not to be.
And among countless others I shall bear him in mind with admiration and affection.
You yourself will be much in our sympathetic thoughts.
I beg you not to attempt any acknowledgement of this note.
Yours very sincerely
Herbert Howells
From Gordon Jacob
262. 28th May 1953 Gordon Jacob to DMF
Pine Cottage, Brockenhurst, Hants.
My dear Dora,
Sidney and I were much shocked to see the announcement of Hubert's death in the Times today.
It seems impossible that such a vital personality should have passed away at such an early age. We quite thought that he had recovered from his illness in a remarkable way. He will be very much missed by the wide circle of friends he made in the course of his varied interests to each of which he brought his always youthful and vivid enthusiasm.
Please accept our deepest sympathy,
Yrs sincerely,
Gordon Jacob
From Dora Powell
263. 28th May 1953 Dora Powell to DMF
Poels, East Grinstead, Sussex
Dear Mrs. Foss
I was so shocked and sad to see today's Times. I am so very sorry – & so sorry for you and all the trouble & anxiety that you must have been through. I have known Mr. Foss for so many years and shall never forget his kindness & encouragement over the 1st edition of my Elgar book by the Oxford Press in 1937.
I doubt if I should have got on so well as I have without his help.
Prenatal maternal depression and child serotonin transporter linked polymorphic region (5-HTTLPR) and dopamine receptor D4 (DRD4) genotype predict negative emotionality from 3 to 36 months
- Cathryn Gordon Green, Vanessa Babineau, Alexia Jolicoeur-Martineau, Andrée-Anne Bouvette-Turcot, Klaus Minde, Roberto Sassi, Martin St-André, Normand Carrey, Leslie Atkinson, James L. Kennedy, Meir Steiner, John Lydon, Helene Gaudreau, Jacob A. Burack, Robert Levitan, Michael J. Meaney, Ashley Wazana, The Maternal Adversity, Vulnerability, and Neurodevelopment Research Team
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- Journal:
- Development and Psychopathology / Volume 29 / Issue 3 / August 2017
- Published online by Cambridge University Press:
- 18 July 2016, pp. 901-917
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Prenatal maternal depression and a multilocus genetic profile of two susceptibility genes implicated in the stress response were examined in an interaction model predicting negative emotionality in the first 3 years. In 179 mother–infant dyads from the Maternal Adversity, Vulnerability, and Neurodevelopment cohort, prenatal depression (Center for Epidemiologic Studies Depressions Scale) was assessed at 24 to 36 weeks. The multilocus genetic profile score consisted of the number of susceptibility alleles from the serotonin transporter linked polymorphic region gene (5-HTTLPR): no long-rs25531(A) (LA: short/short, short/long-rs25531(G) [LG], or LG/LG] vs. any LA) and the dopamine receptor D4 gene (six to eight repeats vs. two to five repeats). Negative emotionality was extracted from the Infant Behaviour Questionnaire—Revised at 3 and 6 months and the Early Child Behavior Questionnaire at 18 and 36 months. Mixed and confirmatory regression analyses indicated that prenatal depression and the multilocus genetic profile interacted to predict negative emotionality from 3 to 36 months. The results were characterized by a differential susceptibility model at 3 and 6 months and by a diathesis–stress model at 36 months.
Contributors
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- By Mitchell Aboulafia, Frederick Adams, Marilyn McCord Adams, Robert M. Adams, Laird Addis, James W. Allard, David Allison, William P. Alston, Karl Ameriks, C. Anthony Anderson, David Leech Anderson, Lanier Anderson, Roger Ariew, David Armstrong, Denis G. Arnold, E. J. Ashworth, Margaret Atherton, Robin Attfield, Bruce Aune, Edward Wilson Averill, Jody Azzouni, Kent Bach, Andrew Bailey, Lynne Rudder Baker, Thomas R. Baldwin, Jon Barwise, George Bealer, William Bechtel, Lawrence C. Becker, Mark A. Bedau, Ernst Behler, José A. Benardete, Ermanno Bencivenga, Jan Berg, Michael Bergmann, Robert L. Bernasconi, Sven Bernecker, Bernard Berofsky, Rod Bertolet, Charles J. Beyer, Christian Beyer, Joseph Bien, Joseph Bien, Peg Birmingham, Ivan Boh, James Bohman, Daniel Bonevac, Laurence BonJour, William J. Bouwsma, Raymond D. Bradley, Myles Brand, Richard B. Brandt, Michael E. Bratman, Stephen E. Braude, Daniel Breazeale, Angela Breitenbach, Jason Bridges, David O. Brink, Gordon G. Brittan, Justin Broackes, Dan W. Brock, Aaron Bronfman, Jeffrey E. Brower, Bartosz Brozek, Anthony Brueckner, Jeffrey Bub, Lara Buchak, Otavio Bueno, Ann E. Bumpus, Robert W. Burch, John Burgess, Arthur W. Burks, Panayot Butchvarov, Robert E. Butts, Marina Bykova, Patrick Byrne, David Carr, Noël Carroll, Edward S. Casey, Victor Caston, Victor Caston, Albert Casullo, Robert L. Causey, Alan K. L. Chan, Ruth Chang, Deen K. Chatterjee, Andrew Chignell, Roderick M. Chisholm, Kelly J. Clark, E. J. Coffman, Robin Collins, Brian P. Copenhaver, John Corcoran, John Cottingham, Roger Crisp, Frederick J. Crosson, Antonio S. Cua, Phillip D. Cummins, Martin Curd, Adam Cureton, Andrew Cutrofello, Stephen Darwall, Paul Sheldon Davies, Wayne A. Davis, Timothy Joseph Day, Claudio de Almeida, Mario De Caro, Mario De Caro, John Deigh, C. F. Delaney, Daniel C. Dennett, Michael R. DePaul, Michael Detlefsen, Daniel Trent Devereux, Philip E. Devine, John M. Dillon, Martin C. Dillon, Robert DiSalle, Mary Domski, Alan Donagan, Paul Draper, Fred Dretske, Mircea Dumitru, Wilhelm Dupré, Gerald Dworkin, John Earman, Ellery Eells, Catherine Z. Elgin, Berent Enç, Ronald P. Endicott, Edward Erwin, John Etchemendy, C. Stephen Evans, Susan L. Feagin, Solomon Feferman, Richard Feldman, Arthur Fine, Maurice A. Finocchiaro, William FitzPatrick, Richard E. Flathman, Gvozden Flego, Richard Foley, Graeme Forbes, Rainer Forst, Malcolm R. Forster, Daniel Fouke, Patrick Francken, Samuel Freeman, Elizabeth Fricker, Miranda Fricker, Michael Friedman, Michael Fuerstein, Richard A. Fumerton, Alan Gabbey, Pieranna Garavaso, Daniel Garber, Jorge L. A. Garcia, Robert K. Garcia, Don Garrett, Philip Gasper, Gerald Gaus, Berys Gaut, Bernard Gert, Roger F. Gibson, Cody Gilmore, Carl Ginet, Alan H. Goldman, Alvin I. Goldman, Alfonso Gömez-Lobo, Lenn E. Goodman, Robert M. Gordon, Stefan Gosepath, Jorge J. E. Gracia, Daniel W. Graham, George A. Graham, Peter J. Graham, Richard E. Grandy, I. Grattan-Guinness, John Greco, Philip T. Grier, Nicholas Griffin, Nicholas Griffin, David A. Griffiths, Paul J. Griffiths, Stephen R. Grimm, Charles L. Griswold, Charles B. Guignon, Pete A. Y. Gunter, Dimitri Gutas, Gary Gutting, Paul Guyer, Kwame Gyekye, Oscar A. Haac, Raul Hakli, Raul Hakli, Michael Hallett, Edward C. Halper, Jean Hampton, R. James Hankinson, K. R. Hanley, Russell Hardin, Robert M. Harnish, William Harper, David Harrah, Kevin Hart, Ali Hasan, William Hasker, John Haugeland, Roger Hausheer, William Heald, Peter Heath, Richard Heck, John F. Heil, Vincent F. Hendricks, Stephen Hetherington, Francis Heylighen, Kathleen Marie Higgins, Risto Hilpinen, Harold T. Hodes, Joshua Hoffman, Alan Holland, Robert L. Holmes, Richard Holton, Brad W. Hooker, Terence E. Horgan, Tamara Horowitz, Paul Horwich, Vittorio Hösle, Paul Hoβfeld, Daniel Howard-Snyder, Frances Howard-Snyder, Anne Hudson, Deal W. Hudson, Carl A. Huffman, David L. Hull, Patricia Huntington, Thomas Hurka, Paul Hurley, Rosalind Hursthouse, Guillermo Hurtado, Ronald E. Hustwit, Sarah Hutton, Jonathan Jenkins Ichikawa, Harry A. Ide, David Ingram, Philip J. Ivanhoe, Alfred L. Ivry, Frank Jackson, Dale Jacquette, Joseph Jedwab, Richard Jeffrey, David Alan Johnson, Edward Johnson, Mark D. Jordan, Richard Joyce, Hwa Yol Jung, Robert Hillary Kane, Tomis Kapitan, Jacquelyn Ann K. Kegley, James A. Keller, Ralph Kennedy, Sergei Khoruzhii, Jaegwon Kim, Yersu Kim, Nathan L. King, Patricia Kitcher, Peter D. Klein, E. D. Klemke, Virginia Klenk, George L. Kline, Christian Klotz, Simo Knuuttila, Joseph J. Kockelmans, Konstantin Kolenda, Sebastian Tomasz Kołodziejczyk, Isaac Kramnick, Richard Kraut, Fred Kroon, Manfred Kuehn, Steven T. Kuhn, Henry E. Kyburg, John Lachs, Jennifer Lackey, Stephen E. Lahey, Andrea Lavazza, Thomas H. Leahey, Joo Heung Lee, Keith Lehrer, Dorothy Leland, Noah M. Lemos, Ernest LePore, Sarah-Jane Leslie, Isaac Levi, Andrew Levine, Alan E. Lewis, Daniel E. Little, Shu-hsien Liu, Shu-hsien Liu, Alan K. L. Chan, Brian Loar, Lawrence B. Lombard, John Longeway, Dominic McIver Lopes, Michael J. Loux, E. J. Lowe, Steven Luper, Eugene C. Luschei, William G. Lycan, David Lyons, David Macarthur, Danielle Macbeth, Scott MacDonald, Jacob L. Mackey, Louis H. Mackey, Penelope Mackie, Edward H. Madden, Penelope Maddy, G. B. Madison, Bernd Magnus, Pekka Mäkelä, Rudolf A. Makkreel, David Manley, William E. Mann (W.E.M.), Vladimir Marchenkov, Peter Markie, Jean-Pierre Marquis, Ausonio Marras, Mike W. Martin, A. P. Martinich, William L. McBride, David McCabe, Storrs McCall, Hugh J. McCann, Robert N. McCauley, John J. McDermott, Sarah McGrath, Ralph McInerny, Daniel J. McKaughan, Thomas McKay, Michael McKinsey, Brian P. McLaughlin, Ernan McMullin, Anthonie Meijers, Jack W. Meiland, William Jason Melanson, Alfred R. Mele, Joseph R. Mendola, Christopher Menzel, Michael J. Meyer, Christian B. Miller, David W. Miller, Peter Millican, Robert N. Minor, Phillip Mitsis, James A. Montmarquet, Michael S. Moore, Tim Moore, Benjamin Morison, Donald R. Morrison, Stephen J. Morse, Paul K. Moser, Alexander P. D. Mourelatos, Ian Mueller, James Bernard Murphy, Mark C. Murphy, Steven Nadler, Jan Narveson, Alan Nelson, Jerome Neu, Samuel Newlands, Kai Nielsen, Ilkka Niiniluoto, Carlos G. Noreña, Calvin G. Normore, David Fate Norton, Nikolaj Nottelmann, Donald Nute, David S. Oderberg, Steve Odin, Michael O’Rourke, Willard G. Oxtoby, Heinz Paetzold, George S. Pappas, Anthony J. Parel, Lydia Patton, R. P. Peerenboom, Francis Jeffry Pelletier, Adriaan T. Peperzak, Derk Pereboom, Jaroslav Peregrin, Glen Pettigrove, Philip Pettit, Edmund L. Pincoffs, Andrew Pinsent, Robert B. Pippin, Alvin Plantinga, Louis P. Pojman, Richard H. Popkin, John F. Post, Carl J. Posy, William J. Prior, Richard Purtill, Michael Quante, Philip L. Quinn, Philip L. Quinn, Elizabeth S. Radcliffe, Diana Raffman, Gerard Raulet, Stephen L. Read, Andrews Reath, Andrew Reisner, Nicholas Rescher, Henry S. Richardson, Robert C. Richardson, Thomas Ricketts, Wayne D. Riggs, Mark Roberts, Robert C. Roberts, Luke Robinson, Alexander Rosenberg, Gary Rosenkranz, Bernice Glatzer Rosenthal, Adina L. Roskies, William L. Rowe, T. M. Rudavsky, Michael Ruse, Bruce Russell, Lilly-Marlene Russow, Dan Ryder, R. M. Sainsbury, Joseph Salerno, Nathan Salmon, Wesley C. Salmon, Constantine Sandis, David H. Sanford, Marco Santambrogio, David Sapire, Ruth A. Saunders, Geoffrey Sayre-McCord, Charles Sayward, James P. Scanlan, Richard Schacht, Tamar Schapiro, Frederick F. Schmitt, Jerome B. Schneewind, Calvin O. Schrag, Alan D. Schrift, George F. Schumm, Jean-Loup Seban, David N. Sedley, Kenneth Seeskin, Krister Segerberg, Charlene Haddock Seigfried, Dennis M. Senchuk, James F. Sennett, William Lad Sessions, Stewart Shapiro, Tommie Shelby, Donald W. Sherburne, Christopher Shields, Roger A. Shiner, Sydney Shoemaker, Robert K. Shope, Kwong-loi Shun, Wilfried Sieg, A. John Simmons, Robert L. Simon, Marcus G. Singer, Georgette Sinkler, Walter Sinnott-Armstrong, Matti T. Sintonen, Lawrence Sklar, Brian Skyrms, Robert C. Sleigh, Michael Anthony Slote, Hans Sluga, Barry Smith, Michael Smith, Robin Smith, Robert Sokolowski, Robert C. Solomon, Marta Soniewicka, Philip Soper, Ernest Sosa, Nicholas Southwood, Paul Vincent Spade, T. L. S. Sprigge, Eric O. Springsted, George J. Stack, Rebecca Stangl, Jason Stanley, Florian Steinberger, Sören Stenlund, Christopher Stephens, James P. Sterba, Josef Stern, Matthias Steup, M. A. Stewart, Leopold Stubenberg, Edith Dudley Sulla, Frederick Suppe, Jere Paul Surber, David George Sussman, Sigrún Svavarsdóttir, Zeno G. Swijtink, Richard Swinburne, Charles C. Taliaferro, Robert B. Talisse, John Tasioulas, Paul Teller, Larry S. Temkin, Mark Textor, H. S. Thayer, Peter Thielke, Alan Thomas, Amie L. Thomasson, Katherine Thomson-Jones, Joshua C. Thurow, Vzalerie Tiberius, Terrence N. Tice, Paul Tidman, Mark C. Timmons, William Tolhurst, James E. Tomberlin, Rosemarie Tong, Lawrence Torcello, Kelly Trogdon, J. D. Trout, Robert E. Tully, Raimo Tuomela, John Turri, Martin M. Tweedale, Thomas Uebel, Jennifer Uleman, James Van Cleve, Harry van der Linden, Peter van Inwagen, Bryan W. Van Norden, René van Woudenberg, Donald Phillip Verene, Samantha Vice, Thomas Vinci, Donald Wayne Viney, Barbara Von Eckardt, Peter B. M. Vranas, Steven J. Wagner, William J. Wainwright, Paul E. Walker, Robert E. Wall, Craig Walton, Douglas Walton, Eric Watkins, Richard A. Watson, Michael V. Wedin, Rudolph H. Weingartner, Paul Weirich, Paul J. Weithman, Carl Wellman, Howard Wettstein, Samuel C. Wheeler, Stephen A. White, Jennifer Whiting, Edward R. Wierenga, Michael Williams, Fred Wilson, W. Kent Wilson, Kenneth P. Winkler, John F. Wippel, Jan Woleński, Allan B. Wolter, Nicholas P. Wolterstorff, Rega Wood, W. Jay Wood, Paul Woodruff, Alison Wylie, Gideon Yaffe, Takashi Yagisawa, Yutaka Yamamoto, Keith E. Yandell, Xiaomei Yang, Dean Zimmerman, Günter Zoller, Catherine Zuckert, Michael Zuckert, Jack A. Zupko (J.A.Z.)
- Edited by Robert Audi, University of Notre Dame, Indiana
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- Book:
- The Cambridge Dictionary of Philosophy
- Published online:
- 05 August 2015
- Print publication:
- 27 April 2015, pp ix-xxx
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Contributors
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- By Thomas M. Achenbach, Steven Arnocky, Christine Blain-Arcaro, Amy Bombay, Nancy Brady, Jacob A. Burack, Tony Charman, Xinyin Chen, Lauren Drvaric, Heidi Flores, Stephanie A. Fryberg, Jan S. Greenberg, Jennifer Hepditch, Jinkuk Hong, Jennifer M. Knack, Amanda Krygsman, Christine L. Lackner, Peter A. Leavitt, Marsha Mailick, Matilda E. Nowakowski, Vladimir Ponizovsky, Louis A. Schmidt, Sidney J. Segalowitz, Leann E. Smith, Audra Sterling, Jillian Stewart, Wendy Troop-Gordon, Tracy Vaillancourt, Ryan J. van Lieshout, Irene Vitoroulis, Steven F. Warren, Jordana Waxman, Fan Yang, Siman Zhao
- Edited by Jacob A. Burack, McGill University, Montréal, Louis A. Schmidt, McMaster University, Ontario
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- Book:
- Cultural and Contextual Perspectives on Developmental Risk and Well-Being
- Published online:
- 05 June 2014
- Print publication:
- 26 May 2014, pp xiii-xiv
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Teaching the African Experience: A Pan-Africanist Approach
- Jacob U. Gordon
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- Journal:
- African Studies Review / Volume 19 / Issue 3 / December 1976
- Published online by Cambridge University Press:
- 23 May 2014, pp. 109-117
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The pioneering book The Negro, by W.E.B. Du Bois (1915), more than fifty years ago claimed a place for Africa in world history and opened the whole field of black historiography. It is fair to say that until its publication in 1915 the serious study of Africans at home and abroad had been neglected. Aspects of African and black American history had been surveyed but no synoptic view of Africans and people of African descent throughout the world had been undertaken, nor had the black man's right to be considered an integral part of human history been established. The originality of the book lies in its attempt “to pull together into one succinct but comprehensive whole the different elements of African history.” What we now frequently refer to as the “African Diaspora” still challenges historians, and it seems that there has not yet appeared a general history of the black race that goes much further than The Negro. It is equally important to note here that not much has been done in terms of the development of comprehensive African studies centers. As a matter of fact, I believe—although many Africanists, I know, would disagree with me—that the failure of African area studies centers to develop programs which embrace “The Black Diaspora” was partly responsible for the birth of separate Afro-American studies departments and Afro-Caribbean studies departments in the 1960s. This apparent lack of a Pan-Africanist perspective in African studies programs has created problems yet to be dealt with by American academia.
Development of a Modified Surveillance Definition of Central Line–Associated Bloodstream Infections for Patients with Hematologic Malignancies
- Megan J. DiGiorgio, Cynthia Fatica, Mary Oden, Brian Bolwell, Mikkael Sekeres, Matt Kalaycio, Patti Akins, Christina Shane, Jacob Bako, Steven M. Gordon, Thomas G. Fraser
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- Journal:
- Infection Control & Hospital Epidemiology / Volume 33 / Issue 9 / September 2012
- Published online by Cambridge University Press:
- 02 January 2015, pp. 865-868
- Print publication:
- September 2012
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Objective.
To develop a modified surveillance definition of central line-associated bloodstream infection (mCLABSI) specific for our population of patients with hematologic malignancies to better support ongoing improvement efforts at our hospital.
Design.Retrospective cohort study.
Patients.Hematologic malignancies population in a 1,200-bed tertiary care hospital on a 22-bed bone marrow transplant (BMT) unit and a 22-bed leukemia unit.
Methods.An mCLABSI definition was developed, and pathogens and rates were compared against those determined using the National Healthcare Safety Network (NHSN) definition.
Results.By the NHSN definition the CLABSI rate on the BMT unit was 6.0 per 1,000 central line-days, and by the mCLABSI definition the rate was 2.0 per 1,000 line-days (P < .001). On the leukemia unit, the NHSN CLABSI rate was 14.4 per 1,000 line-days, and the mCLABSI rate was 8.2 per 1,000 line-days (P = .009). The top 3 CLABSI pathogens by the NHSN definition were Enterococcus species, Klebsiella species, and Escherichia coli. The top 3 CLABSI pathogens by the mCLABSI definition were coagulase-negative Staphylococcus (CONS), Pseudomonas aeruginosa, and Staphylococcus aureus. The difference in the incidence of CONS as a cause of CLABSI under the 2 definitions was statistically significant (P < .001).
Conclusions.A modified surveillance definition of CLABSI was associated with an increase in the identification of staphylococci as the cause of CLABSIs, as opposed to enteric pathogens, and a decrease in CLABSI rates.
Surgical correction for patients with tetralogy of Fallot and common atrioventricular junction
- Marco Ricci, Christo I. Tchervenkov, Jeffrey P. Jacobs, Robert H. Anderson, Gordon Cohen, Edward L. Bove
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- Journal:
- Cardiology in the Young / Volume 18 / Issue S3 / December 2008
- Published online by Cambridge University Press:
- 01 December 2008, pp. 29-38
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HIGH-SURFACE-AREA BIOCARBONS FOR REVERSIBLE ON-BOARD STORAGE OF NATURAL GAS AND HYDROGEN
- Peter Pfeifer, Jacob W. Burress, Mikael B. Wood, Cintia M. Lapilli, Sarah A. Barker, Jeffrey S. Pobst, Raina J. Cepel, Carlos Wexler, Parag S. Shah, Michael J. Gordon, Galen J. Suppes, S. Philip Buckley, Darren J. Radke, Jan Ilavsky, Anne C. Dillon, Philip A. Parilla, Michael Benham, Michael W. Roth
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- Journal:
- MRS Online Proceedings Library Archive / Volume 1041 / 2007
- Published online by Cambridge University Press:
- 01 February 2011, 1041-R02-02
- Print publication:
- 2007
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An overview is given of the development of advanced nanoporous carbons as storage ma-terials for natural gas (methane) and molecular hydrogen in on-board fuel tanks for next-generation clean automobiles. The carbons are produced in a multi-step process from corncob, have surface areas of up to 3500 m2/g, porosities of up to 0.8, and reversibly store, by physisorp-tion, record amounts of methane and hydrogen. Current best gravimetric and volumetric storage capacities are: 250 g CH4/kg carbon and 130 g CH4/liter carbon (199 V/V) at 35 bar and 293 K; and 80 g H2/kg carbon and 47 g H2/liter carbon at 47 bar and 77 K. This is the first time the DOE methane storage target of 180 V/V at 35 bar and ambient temperature has been reached and exceeded. The hydrogen values compare favorably with the 2010 DOE gravimetric and volu-metric targets for hydrogen. A prototype adsorbed natural gas (ANG) tank, loaded with carbon monoliths produced accordingly and currently undergoing a road test in Kansas City, is de-scribed. A preliminary analysis of the surface and pore structure is given that may shed light on the mechanisms leading to the extraordinary storage capacities of these materials. The analysis includes pore-size distributions from nitrogen adsorption isotherms; spatial organization of pores across the entire solid from small-angle x-ray scattering (SAXS); pore entrances from scanning electron microscopy (SEM) and transmission electron microscopy (TEM); H2 binding energies from temperature-programmed desorption (TPD); and analysis of surface defects from Raman spectra. For future materials, expected to have higher H2 binding energies via appropriate sur-face functionalization, preliminary projections of H2 storage capacities based on molecular dy-namics simulations of adsorption of H2 on graphite, are reported.
Creating a database with cardioscopy and intra-operative imaging
- Jeffrey P. Jacobs, Martin J. Elliott, Robert H. Anderson, James A. Quintessenza, Paul J. Chai, Victor O. Morell, Luis M. Botero, Hugh M. van Gelder, Vinay Badhwar, Mazzy Kanani, Gordon A. Cohen, Redmond P. Burke
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- Journal:
- Cardiology in the Young / Volume 15 / Issue S1 / February 2005
- Published online by Cambridge University Press:
- 08 September 2005, pp. 184-189
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The abilities for both computer technology, and intra-operative video-imaging, are evolving rapidly. The merger of these two sciences can be very beneficial, both to congenital cardiac surgeons in general, and in facilitating the creation of a cardioscopic database in particular.
Interferometry of pulsating red giants from 0.65 to 3.5 microns
- Michael Ireland, Peter Tuthill, Gordon Robertson, Timothy Bedding, Andrew Jacob, John Monnier, William Danchi
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- Journal:
- International Astronomical Union Colloquium / Volume 193 / 2004
- Published online by Cambridge University Press:
- 12 April 2016, pp. 327-331
- Print publication:
- 2004
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We present the results of two multi-wavelength studies of the angular diameters of the Mira-like stars ο Cet, W Hya and R Leo. The MAPPIT experiment was able to deliver diameters of these stars over a continuous wavelength region from 0.65 – 1 micron, while the Keck aperture-masking experiment was able to deliver diameters between 1.2 and 3.5 microns. Strong size variations with wavelength were recorded for all stars, and we discuss the implications for model atmospheres of these stars, and speculate on the necessity of including dust scattering in radiative transfer calculations.
The Accuracy of the ICRF: an Intercomparison of VLBI Analysis Software
- C.S. Jacobs, O.J. Sovers, D. Gordon, C. Ma, A.-M. Gontier
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- Journal:
- Highlights of Astronomy / Volume 11 / Issue 1 / 1998
- Published online by Cambridge University Press:
- 14 August 2015, pp. 320-321
- Print publication:
- 1998
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As discussed in other papers in this volume, the IAU XXIII General Assembly adopted a new fundamental celestial reference frame: the International Celestial Reference Frame (ICRF) based on VLBI observations of extragalactic radio sources (Ma et al., 1997). It is approximately 300 times more accurate than its predecessor, the FK5. At present, no other technique has produced a more accurate celestial frame than VLBI, Since no other astrometric technique provides an external standard of accuracy, the VLBI claim of a great leap forward in accuracy must be verified by internal consistency tests. This paper addresses one aspect of internal consistency: the ability of independent VLBI software packages to reproduce a celestial frame without significant loss of accuracy. This is no small task since the software packages are large - involving on the order of 100 000 lines of code. What does VLBI software do? Aside from routines designed to collect the data and extract raw observables which will not be considered here, its principal task is to model the differential group delay and phase delay rate of radio signals received at two widely separated antennas (Sovers, Fanselow & Jacobs, 1998). The software then refines this model via a least squares adjustment of relevant physical parameters which describe station locations, source positions, clock offsets, atmospheric refraction, tidal effects, etc. In the early 1990s, studies revealed that differences in software implementation and analyst’s choices of model options were one of the largest contributors to differences in independent calculations of VLBI celestial frames. These differences were of comparable size to the formal uncertainties of the celestial frame’s source positions.