We develop the distinction between “referential” and “modalizing” aspects of language and describe their functional dissociation, as observed in various manifestations of aphasia and in the speech of hemispherectomy and commissurotomy patients. Such a frequently observable dissociation is taken to reflect certain cognitive and neurobiological distinctions that do not seem to be accounted for by the structurally motivated linguistic models currently utilized in neurolinguistic studies. The dissociation appears to generate fresh and original insights when applied to acquired language impairments.