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Debate 43A - Is Radical Surgery or Parametrectomy Needed for Early-stage FIGO IA2 and Microscopic IB1 Cervical Cancer?

Yes

from Section V - Cervical Cancer

Published online by Cambridge University Press:  20 July 2023

Dennis S. Chi
Affiliation:
Memorial Sloan-Kettering Cancer Center, New York
Nisha Lakhi
Affiliation:
Richmond University Medical Center, Staten Island
Nicoletta Colombo
Affiliation:
University of Milan-Bicocca
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Summary

Approximately 80% of cases of cervical cancer are diagnosed at an early stage, when it is amenable to perform radical surgery. Radical surgery is characterized by parametrectomy, which involves the excision of parametrial tissues, including the ventral (the vesicouterine and vesicovaginal ligaments), lateral (the cardinal ligament), and dorsal (the uterosacral and rectovaginal ligaments) parts of parametrial or paracervical tissues. Insufficient excision is associated with an increased risk of cancer recurrence, whereas excessive excision is associated with an increased risk of surgical morbidity. The extent of parametrectomy should be tailored according to the extent of the cancer.

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Publisher: Cambridge University Press
Print publication year: 2023

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References

Panici, PB, et al. Tailoring the parametrectomy in stages IA2-IB1 cervical carcinoma: is it feasible and safe? Gynecol Oncol 2005;96:792798.CrossRefGoogle ScholarPubMed
Frumovitz, M, et al. Parametrial involvement in radical hysterectomy specimens for women with early-stage cervical cancer. Obstet Gynecol 2009;114:9399.CrossRefGoogle ScholarPubMed
Park, JY, et al. Management of occult invasive cervical cancer found after simple hysterectomy. Ann Oncol 2010;21:9941000.CrossRefGoogle ScholarPubMed
Sia, TY, et al. Trends in use and effect on survival of simple hysterectomy for early-stage cervical cancer. Obstet Gynecol 2019;134:11321143.CrossRefGoogle ScholarPubMed
Wu, J, et al. Less-radical surgery for early-stage cervical cancer: a systematic review. Am J Obstet Gynecol 2021;224(4):348–358.e5.CrossRefGoogle ScholarPubMed
Ramirez, PT, et al. Minimally invasive versus abdominal radical hysterectomy for cervical cancer. N Engl J Med 2018;379:1895–1904.Google Scholar

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