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Section I - Peripheral Blood

Published online by Cambridge University Press:  25 November 2023

Edited by
Silvia Tse Bunting ,
Xiayuan Liang ,
Michele E. Paessler  and
Satheesh Chonat
Silvia Tse Bunting
Affiliation:
Cleveland Clinic Florida Weston
Xiayuan Liang
Affiliation:
University of Colorado
Michele E. Paessler
Affiliation:
University of Pennsylvania School of Medicine
Satheesh Chonat
Affiliation:
Emory University, Atlanta
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Atlas of Pediatric Hematopathology , pp. 1 - 30
Publisher: Cambridge University Press
Print publication year: 2023

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References

References

Gulati, G, Song, J, Florea, AD, Gong, J. Purpose and criteria for blood smear scan, blood smear examination, and blood smear review. Ann Lab Med. 2013; 33(1): 1–7.CrossRefGoogle ScholarPubMed
Bain, BJ. Diagnosis from the blood smear. N Engl J Med. 2005; 353: 498–507.CrossRefGoogle ScholarPubMed
Steiner, LA, Gallagher, PG. Erythrocyte disorders in the perinatal period. Semin Perinatol. 2007; 31(4): 254–61.CrossRefGoogle ScholarPubMed
Lawrence, SM, Corriden, R, Nizet, V. Age-appropriate functions and dysfunctions of the neonatal neutrophil. Front Pediatr. 2017; 5: 23.CrossRefGoogle ScholarPubMed
Kühne, T, Imbach, P. Neonatal platelet physiology and pathophysiology. Eur J Pediatr. 1998; 157(2): 87–94.CrossRefGoogle ScholarPubMed
Sakka, V, Tsiodras, S, Giamarellos-Bourboulis, EJ, Giamarellou, H. An update on the etiology and diagnostic evaluation of a leukemoid reaction. Eur J Intern Med. 2006; 17(6): 394–8.CrossRefGoogle ScholarPubMed
Aird, WC. The hematologic system as a marker of organ dysfunction in sepsis. Mayo Clin Proc. 2003; 78(7): 869–81.CrossRefGoogle ScholarPubMed
Chonat, S, Graciaa, S, Shin, HS, Newton, JG, Quarmyne, MO, Boudreaux, J, et al. Eculizumab for complement mediated thrombotic microangiopathy in sickle cell disease. Haematologica. 2020. Dec 1; 105(12): 2887–91.Google ScholarPubMed
Reykdal, S, Sham, R, Phatak, P, Kouides, P. Pseudoleukemia following the use of G-CSF. Am J Hematol. 1995; 49(3): 258–9.CrossRefGoogle ScholarPubMed
Nazarullah, A, Liang, C, Villarreal, A, Higgins, RA, Mais, DD. Peripheral blood examination findings in SARS-Co-V-2 infection. AM J Clin Pathol. 2020; 154(3): 319–29.CrossRefGoogle Scholar
Berber, I, Cagascar, O, Sarici, A, Berber, NK, Aydogdu, I, Ulutas, O, et al. Peripheral blood smear findings of COVID-19 patients provide information about the severity of the disease and the duration of the hospital stay. Mediterr J Hematol Infect Dis. 2021; 13(1): e2021009.CrossRefGoogle Scholar
Diorio, C, Henrickson, SE, Vella, LA, McNerney, KO, Chase, J, Burudpakdee, C, et al. Multisystem inflammatory syndrome in children and COVID-19 are distinct presentations of SARS-CoV-2. J Clin Invest. 2020; 130(11): 5967–75.CrossRefGoogle ScholarPubMed
Merino, A, Vlagea, A, Molina, A, Egri, N, Laguna, J, Barrera, K, et al. Atypical lymphoid cells circulating in blood in COVID-19 infection: Morphology, immunophenotype and prognosis value. J Clin Pathol. 2020; 75(2): 104–11.Google ScholarPubMed

References

Beutler, E. G6PD deficiency. Blood. 1994; 84(11): 3613–36.CrossRefGoogle ScholarPubMed
Beutler, E, Gelbart, T. Estimating the prevalence of pyruvate kinase deficiency from the gene frequency in the general white population. Blood. 2000; 95(11): 3585–8.CrossRefGoogle ScholarPubMed
Koralkova, P, Van Solinge, WW, Van Wijk, R. Rare hereditary red blood cell enzymopathies associated with hemolytic anemia: Pathophysiology, clinical aspects, and laboratory diagnosis. Int J Lab Hematol. 2014; 36(3): 388–97.CrossRefGoogle ScholarPubMed
Risinger, M, Kalfa, TA. Red cell membrane disorders: Structure meets function. Blood. 2020; 136(11): 1250–61.CrossRefGoogle ScholarPubMed
Caruso, C, Chonat, S. Immune and nonimmune hemolytic anemia. In Kamat, D, Frei-Jones, M, eds. Benign hematologic disorders in children. Cham: Springer; 2021: 51–64. https://doi.org/10.1007/978-3-030-49980-8_4.CrossRefGoogle Scholar
Berentsen, S, Barcellini, W. Autoimmune hemolytic anemias. N Engl J Med. 2021 Oct 7; 385(15): 1407–19.CrossRefGoogle ScholarPubMed

References

Lisman, T. Platelet-neutrophil interactions as drivers of inflammatory and thrombotic disease. Cell Tissue Res. 2018; 371(3): 567–76.CrossRefGoogle ScholarPubMed
Kaplan, J, De Domenico, I, Ward, DM. Chediak-Higashi syndrome. Curr Opin Hematol. 2008; 15(1): 22–9.CrossRefGoogle ScholarPubMed
Jessen, B, Maul-Pavicic, A, Ufheil, H, Vraetz, T, Enders, A, Lehmberg, K, et al. Subtle differences in CTL cytotoxicity determine susceptibility to hemophagocytic lymphohistiocytosis in mice and humans with Chediak-Higashi syndrome. Blood. 2011; 118(17): 4620–9.CrossRefGoogle ScholarPubMed
Liu, Q, Pan, C, Lopez, L, Gao, J, Velez, D, Anaya-O’Brien, S, et al. WHIM syndrome caused by Waldenström’s macroglobulinemia-associated mutation CXCR4 (L329fs). J Clin Immunol. 2016; 36(4): 397–405.CrossRefGoogle ScholarPubMed
Badolato, R, Donadieu, J. How I treat warts, hypogammaglobulinemia, infections, and myelokathexis syndrome. Blood. 2017; 130(23): 2491–8.CrossRefGoogle Scholar
Badolato, R, Dotta, L, Tassone, L, Amendola, G, Porta, F, Locatelli, F, et al. Tetralogy of Fallot is an uncommon manifestation of warts, hypogammaglobulinemia, infections, and myelokathexis syndrome. J Pediatr. 2012; 161(4): 763–5.CrossRefGoogle ScholarPubMed
McDermott, DH, Liu, Q, Ulrick, J, Kwatemaa, N, Anaya-O’Brien, S, Penzak, SR, et al. The CXCR4 antagonist plerixafor corrects panleukopenia in patients with WHIM syndrome. Blood. 2011; 118(18): 4957–62.CrossRefGoogle ScholarPubMed
Kunishima, S. [May-Hegglin anomaly: Past and present: MNovel diagnostic test and new concept of the disease]. Rinsho Byori. 2009; 57(1): 54–9.Google ScholarPubMed
Barros Pinto, MP, Marques, G. MYH9 disorders (May-Hegglin anomaly): The role of the blood smear. J Pediatr Hematol Oncol. 2019; 41(3): 228.CrossRefGoogle ScholarPubMed
Clarke, SL, Bowron, A, Gonzalez, IL, Groves, SJ, Newbury-Ecob, R, Clayton, N, et al. Barth syndrome. Orphanet J Rare Dis. 2013; 8: 23.CrossRefGoogle ScholarPubMed
Ikon, N, Ryan, RO. Barth syndrome: Connecting cardiolipin to cardiomyopathy. Lipids. 2017; 52(2): 99–108.CrossRefGoogle ScholarPubMed
Diz-Kücükkaya, R, López, JA. Inherited disorders of platelets: Membrane glycoprotein disorders. Hematol Oncol Clin North Am. 2013; 27(3): 613–27.CrossRefGoogle ScholarPubMed
Gunay-Aygun, M, Falik-Zaccai, TC, Vilboux, T, Zivony-Elboum, Y, Gumruk, F, Cetin, M, et al. NBEAL2 is mutated in gray platelet syndrome and is required for biogenesis of platelet α-granules. Nat Genet. 2011; 43(8): 732–4.CrossRefGoogle ScholarPubMed
De Jesus Rojas, W, Young, LR. Hermansky-Pudlak syndrome. Semin Respir Crit Care Med. 2020; 41(2): 238–46.Google ScholarPubMed
Huizing, M, Malicdan, MCV, Wang, JA, Pri-Chen, H, Hess, RA, Fischer, R, et al. Hermansky-Pudlak syndrome: Mutation update. Hum Mutat. 2020; 41(3):543–80.CrossRefGoogle ScholarPubMed
LeVine, DN, Brooks, MB. Immune thrombocytopenia (ITP): Pathophysiology update and diagnostic dilemmas. Vet Clin Pathol. 2019; 48 Suppl 1: 17–28.CrossRefGoogle ScholarPubMed
Massaad, MJ, Ramesh, N, Geha, RS. Wiskott-Aldrich syndrome: A comprehensive review. Ann N Y Acad Sci. 2013; 1285: 26–43.CrossRefGoogle ScholarPubMed
Chiasakul, T, Cuker, A. Clinical and laboratory diagnosis of TTP: An integrated approach. Hematology Am Soc Hematol Educ Program. 2018; 2018(1): 530–8.Google ScholarPubMed
George, JN. Congenital TTP: Toward a turning point. Blood. 2019; 133(15): 1615–17.CrossRefGoogle ScholarPubMed

References

Graciaa, S, Russell, R, Chonat, S. Complement mediated hemolytic anemia secondary to plasmodium ovale infection in a child. J Pediatr Hematol Oncol. 2019; 41(7): 557–8.CrossRefGoogle ScholarPubMed
Tsai, MH, Yu, SS, Chan, YK, Jen, CC. Blood smear image based malaria parasite and infected-erythrocyte detection and segmentation. J Med Syst. 2015; 39(10): 118.CrossRefGoogle ScholarPubMed
Pandey, S, Cetin, N. Peripheral smear clues for Bordetella pertussis. Blood. 2013; 122(25): 4012.CrossRefGoogle ScholarPubMed
Hamilton, KS, Standaert, SM, Kinney, MC. Characteristic peripheral blood findings in human ehrlichiosis. Mod Pathol. 2004; 17(5): 512–17.CrossRefGoogle ScholarPubMed
Dapul, H, Laraque, D. Lead poisoning in children. Adv Pediatr. 2014; 61(1): 313–33.CrossRefGoogle ScholarPubMed

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