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10 - CMOS nanowire biosensing systems

from Part II - Biosensors

Published online by Cambridge University Press:  05 September 2015

By
Monika Weber ,
Jason M. Criscione ,
Xuexin Duan ,
Tarek M. Fahmy ,
Jason Park ,
Nitin K. Rajan ,
David A. Routenberg ,
Erin Steenblock ,
Eric Stern  and
Aleksandar Vacic
...Show all authors
Edited by
Sandro Carrara  and
Krzysztof Iniewski
Monika Weber
Affiliation:
Yale University
Jason M. Criscione
Affiliation:
Yale University
Xuexin Duan
Affiliation:
Tianjin University
Tarek M. Fahmy
Affiliation:
Yale University
Jason Park
Affiliation:
Yale University
Nitin K. Rajan
Affiliation:
Yale University
David A. Routenberg
Affiliation:
Yale University
Erin Steenblock
Affiliation:
Yale University
Eric Stern
Affiliation:
Yale University
Aleksandar Vacic
Affiliation:
Yale University
Mark A. Reed
Affiliation:
Yale University
Sandro Carrara
Affiliation:
École Polytechnique Fédérale de Lausanne
Krzysztof Iniewski
Affiliation:
Redlen Technologies Inc., Canada
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Summary

Introduction

Lowering the costs of healthcare and increasing its accessibility is a critical need of today’s society. Miniaturized electronic sensors are a possible way to both improve healthcare and lower the cost of medical diagnostics. Their small size and portability can lead to integration into personalized diagnostics tools and emergency care. In addition, faster, smaller and more efficient sensors can greatly impact chemical and biological safety.

The rapid progress demonstrated in the computer industry and in genomics is stirring interest for growth and applications in healthcare and safety. The relentless progress and developments in microfabrication predicted by Moore’s law, which forecast that the number of transistors on an integrated circuit would double every two years, has until now been continually producing faster, cheaper, and smaller consumer electronics. An analogous exponential growth in DNA sequencing is even faster than Moore’s law. Ten years ago, it would have taken many months to sequence a human genome. Today, the same task can be completed within one day. This impressive progress is possible owing to innovative applications of microfabrication technologies. If this can be applied to healthcare, it could stimulate a similar evolution, with applications such as early stage detection of biological infection outbreaks and chemical hazards, which could mitigate epidemics tremendously.

Type
Chapter
Information
Handbook of Bioelectronics
Directly Interfacing Electronics and Biological Systems
 , pp. 122 - 136
Publisher: Cambridge University Press
Print publication year: 2015

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