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Part VI - Stroke Rehabilitation and Recovery

Published online by Cambridge University Press:  15 December 2020

Jeffrey L. Saver
Affiliation:
David Geffen School of Medicine, University of Ca
Graeme J. Hankey
Affiliation:
University of Western Australia, Perth
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Stroke Prevention and Treatment
An Evidence-based Approach
, pp. 485 - 550
Publisher: Cambridge University Press
Print publication year: 2020

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References

References

ATTEND Collaborative Group. (2017). Family-led rehabilitation after stroke in India (ATTEND): a randomised controlled trial. Lancet, 390(10094), 588–99. doi:10.1016/S0140-6736(17)31447-2. Epub 2017 Jun 27. Erratum in: Lancet, 2017, 390(10094), 554. PubMed PMID: 28666682.Google Scholar
Barclay-Goddard, R, Stevenson, T, Poluha, W, Thalman, L. (2011). Mental practice for treating upper extremity deficits in individuals with hemiparesis after stroke. Cochrane Database Syst Rev, 5. CD005950. available from: PM:21563146Google Scholar
Berkhemer, O, Fransen, P, Beumer, D, van den Berg, L, Lingsma, H, Yoo, A, et al. (2015). A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med, 372(1), 1120. available from: PM:25517348CrossRefGoogle ScholarPubMed
Bernhardt, J, Dewey, H, Thrift, A, Donnan, G. (2004). Inactive and alone: physical activity within the first 14 days of acute stroke unit care. Stroke, 35(4), 1005–09Google Scholar
Bernhardt, J, English, C, Johnson, L, Cumming, T. (2015a). Early mobilization after stroke: early adoption but limited evidence. Stroke, 46(4), 1141–6 available from: PM:25690544Google Scholar
Bernhardt, J, Langhorne, P, Lindley, R, Thrift, A, Ellery, F, Collier, J, et al. (2015b). Efficacy and safety of very early mobilisation within 24 h of stroke onset (AVERT): a randomised controlled trial. Lancet, 386, (9988), 4655. available from: PM:25892679Google Scholar
Bernhardt, J, Hayward, KS, Kwakkel, G, Ward, NS, Wolf, SL, Borschmann, K, et al. (2017). Agreed definitions and a shared vision for new standards in stroke recovery research: The Stroke Recovery and Rehabilitation Roundtable Taskforce. Neurorehabil Neural Repair, 31(9), 793–9. doi:10.1177/1545968317732668. PubMed PMID: 28934920.Google Scholar
Buma, F, Kwakkel, G, Ramsey, N. (2013). Understanding upper limb recovery after stroke. Restor Neurol Neurosci, 31(6) 707–22. available from: PM:23963341Google Scholar
Cortes, JC, Goldsmith, J, Harran, MD, Xu, J, Kim, N, Schambra, HM, et al. (2017). A short and distinct time window for recovery of arm motor control early after stroke revealed with a global measure of trajectory kinematics. Neurorehabil Neural Repair, 31(6), 552–60. available from: PM 28506149CrossRefGoogle Scholar
Coupar, F, Pollock, A, Rowe, P. Weir, C, Langhorne, P. (2013). Predictors of upper limb recovery after stroke: a systematic review and meta-analysis. Clin Rehabil, 26(4), 291313.Google Scholar
Coupar, F, Pollock, A, van Wijck, F, Morris, J, Langhorne, P. (2010). Simultaneous bilateral training for improving arm function after stroke. Cochrane Database Syst Rev, 4. CD006432. available from: PM:20393947Google Scholar
Cramer, S. 2008a. Repairing the human brain after stroke. II. Restorative therapies. Annul Neurol, 63(5) 549–60.Google Scholar
Cramer, S. 2008b. Repairing the human brain after stroke: I. Mechanisms of spontaneous recovery. Ann Neurol, 63(3) 272–87.Google Scholar
Duncan, P., Sullivan, K., Behrman, A., Azen, S., Wu, S., Nadeau, S., et al. (2011). Body-weight-supported treadmill rehabilitation after stroke. N Engl J Med, 364(21), 2026–36. available from: PM:21612471Google Scholar
English, C, Hillier, S. (2017). Circuit class therapy for improving mobility after stroke. Cochrane Database Syst Rev, 7. CD007513. available from: PM: 28573757Google Scholar
Feigin, VL, Krishnamurthi, RV, Parmar, P, Norrving, B, Mensah, GA, Bennett, DA, et al.; GBD 2013 Writing Group; GBD 2013 Stroke Panel Experts Group. (2015). Update on the global burden of ischemic and hemorrhagic stroke in 1990–2013: the GBD 2013 Study. Neuroepidemiology, 45(3), 161–76. available from: PM 26505981CrossRefGoogle ScholarPubMed
French, B, Thomas, LH, Coupe, J, McMahon, NE, Connell, L, Harrison, J, et al. (2016). Repetitive task training for improving functional ability after stroke. Cochrane Database Syst Rev, 11. CD006073. available from: PM 27841442Google Scholar
Hoonhorst, MHJ, Nijland, RHM, van den Berg, PJS, Emmelot, CH, Kollen, BJ, Kwakkel, G. (2018). Does transcranial magnetic stimulation have an added value to clinical assessment in predicting upper-limb function very early after severe stroke? Neurorehabil Neural Repair, 32(8), 682–90.Google Scholar
Kohrmann, M, Juttler, E, Fiebach, J, Huttner, H, Siebert, S, Schwark, C, et al. (2006). MRI versus CT-based thrombolysis treatment within and beyond the 3 h time window after stroke onset: a cohort study. Lancet Neurol, 5(8), 661–7. available from: PM:16857571CrossRefGoogle ScholarPubMed
Krakauer, JW, Carmichael, ST. (2018). Broken Movement: The Neurobiology of Motor Recovery after Stroke. Cambridge, MA: MIT Press.Google Scholar
Kwakkel, G, Wagenaar, R, Twisk, J, Lankhorst, G, Koetsier, J. (1999). Intensity of leg and arm training after primary middle-cerebral-artery stroke: a randomised trial. Lancet, 354(9174), 191–6.Google Scholar
Kwakkel, G. (2006a). Impact of intensity of practice after stroke: issues for consideration. Disabil Rehabil, 28(13–14), 823–30. available from: PM:16777769Google Scholar
Kwakkel, G. (2015a). Very early mobilisation within 24 hours results in a less favorable outcome at 3 months [commentary 2]. Physiotherapy, 61(4), 220.Google Scholar
Kwakkel, G, Kollen, B. (2007). Predicting improvement in the upper paretic limb after stroke: a longitudinal prospective study. Restor Neurol Neurosci, 25(5–6), 453–60. available from: PM:18334763Google Scholar
Kwakkel, G, Kollen, B. (2013). Predicting activities after stroke: what is clinically relevant? Int J Stroke, 8(1) 2532. available from: PM:23280266Google Scholar
Kwakkel, G, Kollen, B, Twisk, J. (2006b). Impact of time on improvement of outcome after stroke. Stroke, 37(9), 2348–53. available from: PM:16931787Google Scholar
Kwakkel, G, Meskers, C. (2014). Effects of robotic therapy of the arm after stroke. Lancet Neurol, 13(2), 132–3. available from: PM:24382581Google Scholar
Kwakkel, G, van Peppen, R, Wagenaar, R, Wood Dauphinee, S, Richards, C, Ashburn, A, et al. (2004). Effects of augmented exercise therapy time after stroke: a meta-analysis. Stroke, 35(11), 2529–39. available from: PM:15472114CrossRefGoogle ScholarPubMed
Kwakkel, G, van Wegen, EEH. (2017). Family-delivered rehabilitation services at home: is the glass empty? Lancet, 390(10094), 538–9. doi:10.1016/S0140-6736(17)31489-7. Epub 2017 Jun 27. PubMed PMID: 28666681.Google Scholar
Kwakkel, G, Veerbeek, J, van Wegen, E, Wolf, S. (2015b). Constraint-induced movement therapy after stroke. Lancet Neurol, 14(2), 224–34. available from: PM:25772900Google Scholar
Lang CE, Strube MJ, Bland MD, Waddell KJ, Cherry-Allen KM, Nudo RJ, Dromerick AW, Birkenmeier RL. (2016). Dose response of task-specific upper limb training in people at least 6 months poststroke: a phase II, single-blind, randomized, controlled trial. Ann Neurol, 80(3), 342–54. Available from PM: 27447365Google Scholar
Langhorne, P, Baylan, S. (2017). Early Supported Discharge Trialists. Early supported discharge services for people with acute stroke. Cochrane Database Syst Rev, 7. CD000443. available from: PM: 28703869Google Scholar
Langhorne, P, Bernhardt, J, Kwakkel, G. (2011). Stroke rehabilitation. Lancet, 377(9778), 16931702. available from: PM:21571152Google Scholar
Langhorne, P, Collier, JM, Bate, PJ, Thuy, MN, Bernhardt, J. (2018). Very early versus delayed mobilisation after stroke. Cochrane Database Syst Rev, 10. CD006187. doi:10.1002/14651858.CD006187.pub3.Google ScholarPubMed
Langhorne, P. Legg, L. (2003). Evidence behind stroke rehabilitation. J Neurol Neurosurg Psychiatry, 74(Suppl 4), iv18iv21.Google Scholar
Laver, KE, Lange, B, George, S, Deutsch, JE, Saposnik, G, Crotty, M. (2017). Virtual reality for stroke rehabilitation. Cochrane Database Syst Rev, 11. CD008349. available from: PM 29156493Google Scholar
Lazar, R, Minzer, B, Antoniello, D, Festa, J, Krakauer, J, Marshall, R. (2010). Improvement in aphasia scores after stroke is well predicted by initial severity. Stroke, 41(7), 1485–8. available from: PM:20538700Google Scholar
Lejeune, T., Stoquart, G. (2015). The challenge of assessment in rehabilitation. J Rehabil Med, 47, 672. available from: PM:26074394Google Scholar
Lohse, K, Lang, C, Boyd, L. (2014). Is more better? Using metadata to explore dose-response relationships in stroke rehabilitation. Stroke, 45(7), 2053–8. available from: PM:24867924Google Scholar
Mehrholz, J, Pohl, M, Platz, T, Kugler, J, Elsner, B. (2018). Electromechanical and robot-assisted arm training for improving activities of daily living, arm function, and arm muscle strength after stroke. Cochrane Database Syst Rev, 9, CD006876. available from: PM:30175845Google Scholar
Mehrholz, J, Thomas, S, Elsner, B. (2017). Treadmill training and body weight support for walking after stroke. Cochrane Database Syst Rev, 8. CD002840. available from: PM:28815562Google Scholar
Moseley, A, Stark, A, Cameron, I, Pollock, A. (2005). Treadmill training and body weight support for walking after stroke. Cochrane Database Syst Rev, 4. CD002840. available from: PM:16235304Google Scholar
Murphy, T, Corbett, D. (2009). Plasticity during stroke recovery: from synapse to behaviour. Nat Rev Neorosci, 10(12), 861–72.Google Scholar
Nijboer, T, van de Port, I, Schepers, V, Post, M, Visser-Meily, A. (2013). Predicting functional outcome after stroke: the influence of neglect on basic activities in daily living. Front Hum Neurosci, 7, 182.Google Scholar
Nijland, R, van Wegen, E, Harmeling-van der Wel, B, Kwakkel, G. (2010). Presence of finger extension and shoulder abduction within 72 hours after stroke predicts functional recovery: early prediction of functional outcome after stroke: the EPOS cohort study. Stroke, 41(4), 745–50. available from: PM:20167916Google Scholar
Pomeroy, V, King, L, Pollock, A, Baily-Hallam, A, Langhorne, P. (2006). Electrostimulation for promoting recovery of movement or functional ability after stroke. Cochrane Database Syst Rev, 2. CD003241. available from: PM:16625574Google Scholar
Prabhakaran, S, Zarahn, E, Riley, C, Speizer, A, Chong, J, Lazar, R, et al. (2008). Inter-individual variability in the capacity for motor recovery after ischemic stroke. Neurorehabil Neural Repair, 22(1), 6471. available from: PM:17687024Google Scholar
Prabhakaran S, Ruff I, Bernstein RA. (2015). Acute stroke intervention: a systematic review. JAMA, 313(14), 1451–62. Available from: PM: 25871671Google Scholar
Saver JL, Goyal M, van der Lugt A, et al. (2016). Time to treatment with endovascular thrombectomy and outcomes from ischemic stroke: a meta-analysis. JAMA, 316(12),1279–88. Available from: PM: 27673305Google Scholar
Saunders, DH, Sanderson, M, Hayes, S, Kilrane, M, Greig, CA, Brazzelli, M, Mead, GE. (2016). Physical fitness training for stroke patients. Cochrane Database Syst Rev, 3. CD003316. available from: PM 27010219Google ScholarPubMed
Schulz, K, Altman, D, Moher, D. (2010). CONSORT 2010 statement: updated guidelines for reporting parallel group randomised trials. J Clin Epidemiol, 63(8), 834–40. available from: PM:20346629Google Scholar
Scrutinio, D, Lanzillo, B, Guida, P, Mastropasqua, F, Monitillo, V, Pusineri, M, et al. (2017). Development and validation of a predictive model for functional outcome after stroke rehabilitation: the Maugeri model. Stroke, 48(12), 3308–15. available from: PM:29051222Google Scholar
Smith, MC, Barber, PA, Stinear, CM. (2017). The TWIST algorithm predicts time to walking independently after stroke. Neurorehabil Neural Repair, 31(10–11), 955–64. available from: PM 29090654Google Scholar
Stinear, C. (2010). Prediction of recovery of motor function after stroke. Lancet Neurol, 9(12), 1228–32. available from: PM:21035399Google Scholar
Stinear, CM, Byblow, WD, Ackerley, SJ, Smith, MC, Borges, VM, Barber, PA. (2017). PREP2: A biomarker-based algorithm for predicting upper limb function after stroke. Ann Clin Transl Neurol, 4(11), 811–20. available from: PM 29159193Google Scholar
Stinear, CM. (2017). Prediction of motor recovery after stroke: advances in biomarkers. Lancet Neurol, 16(10), 826–36. available from: PM:28920888Google Scholar
Thieme, H, Morkisch, N, Mehrholz, J, Pohl, M, Behrens, J, Borgetto, B, Dohle, C. (2018). Mirror therapy for improving motor function after stroke. Cochrane Database Syst Rev, 7, CD008449. available from: PM:22419334Google Scholar
van de Port, I, Wevers, L, Lindeman, E, Kwakkel, G. (2012). Effects of circuit training as alternative to usual physiotherapy after stroke: randomised controlled trial. BMJ, 344, e2672. available from: PM:22577186Google Scholar
van Delden, A, Beek, PJ, Roerdink, M, Kwakkel, G, Peper, C. (2015). Unilateral and bilateral upper-limb traning interventions after stroke have similar effects on bimanual coupling strength. Neurorehabil Neural Repair, 29(3) 255–67.Google Scholar
van Delden, A, Peper, C, Beek, P, Kwakkel, G. (2012). Unilateral versus bilateral upper limb exercise therapy after stroke: a systematic review. J Rehabil Med, 44 (2), 106117. available from: PM:22266762CrossRefGoogle ScholarPubMed
van Delden, A, Peper, C, Nienhuys, K, Zijp, N, Beek, J, Kwakkel, G. (2013). Unilateral versus bilateral upper limb training after stroke: the Upper Limb Training After Stroke clinical trial. Stroke, 44(9), 2613–16.Google Scholar
van Kordelaar, J, van Wegen, E, Nijland, R, Daffertshofer, A, Kwakkel, G. (2013). Understanding adaptive motor control of the paretic upper limb early poststroke: the EXPLICIT-stroke program. Neurorehabil Neural Repair, 27(9), 854–63. available from: PM:23884015Google Scholar
van der Vliet R, Selles RW, Andrinopoulou ER, Nijland R, Ribbers GM, Frens MA, Meskers C, Kwakkel G. (2020). Predicting upper limb motor impairment recovery after stroke: a mixture model. Ann Neurol, 2020 (in press). Available at PM: 31925838Google Scholar
Veerbeek, J, Koolstra, M, Ket, J, van Wegen, E, Kwakkel, G. (2011a). Effects of augmented exercise therapy on outcome of gait and gait-related activities in the first 6 months after stroke: a meta-analysis. Stroke, 42(11), 3311–15. available from: PM:21998062Google Scholar
Veerbeek, J, Kwakkel, G, van Wegen, E, Ket, J, Heymans, M. (2011b). Early prediction of outcome of activities of daily living after stroke: a systematic review. Stroke, 42(5), 1482–8. available from: PM:21474812Google Scholar
Veerbeek, J, van Wegen, E, Harmeling-van der Wel, B, Kwakkel, G. (2011c). Is accurate prediction of gait in nonambulatory stroke patients possible within 72 hours poststroke? The EPOS study. Neurorehabil Neural Repair, 25(3), 268–74. available from: PM:21186329Google Scholar
Veerbeek, J, van Wegen, E, van Peppen, R, Van der Wees, P, Hendriks, E, Rietberg, M, et al. (2014). What is the evidence for physical therapy poststroke? A systematic review and meta-analysis. PLoS One, 9(2), e87987. available from: PM:24505342Google Scholar
Veerbeek, JM, Langbroek-Amersfoort, AC, van Wegen, EE, Meskers, CG, Kwakkel, G. (2017). Effects of robot-assisted therapy for the upper limb after stroke. Neurorehabil Neural Repair, 31(2), 107–21. doi:10.1177/1545968316666957. Review. PubMed PMID: 27597165.CrossRefGoogle ScholarPubMed
Veerbeek, JM, Winters, C, van Wegen, EEH, Kwakkel, G. (2018). Is the proportional recovery rule applicable to the lower limb after a first-ever ischemic stroke? PLoS One, 13(1), e0189279. available from: PM:29329286CrossRefGoogle Scholar
Vloothuis JDM, Mulder M, Nijland RHM, Goedhart QS, Konijnenbelt M, Mulder H, Hertogh CMPM, van Tulder M, van Wegen EEH, Kwakkel G. (2019). Caregiver-mediated exercises with e-health support for early supported discharge after stroke (CARE4STROKE): a randomized controlled trial. PLoS One, 14(4), e0214241. Available from PM: 30958833Google Scholar
Vloothuis, JDM, Mulder, M, Veerbeek, JM, Konijnenbelt, M, Visser-Meily, JMA, Ket, JCF, et al. (2016). Caregiver-mediated exercises for improving outcomes after stroke. Cochrane Database Syst Rev, 12. CD011058. doi:10.1002/14651858.CD011058.pub2.Google Scholar
Wang X, You S, Sato S, Yang J, Carcel C, Zheng D, Yoshimura S, Anderson CS, Sandset EC, Robinson T, Chalmers J, Sharma VK. (2018). Current status of intravenous tissue plasminogen activator dosage for acute ischaemic stroke: An updated systematic review. Stroke Vasc Neurol, 3(1), 28–33. Available from PM: 29600005Google Scholar
Winters, C, van Wegen, E, Daffertshofer, A, Kwakkel, G. (2015). Generalizability of the proportional recovery model for the upper extremity after an ischemic stroke. Neurorehabil Neural Repair, 29(7), 614–22. available from: PM:25505223Google Scholar
World Health Organization. (2001). International Classification of Functioning, Disability and Health (ICF). Geneva: WHO.Google Scholar

References

Albert, ML, Sparks, RW, Helm, NA. (1973). Melodic intonation therapy for aphasia. Arch Neurol, 29(2)130–1.Google Scholar
Baddeley, AD, Wilson, BA. (1994). When implicit learning fails: amnesia and the problem of error elimination. Neuropsychologia, 32, 5368.Google Scholar
Barker-Collo, S, Feigin, VL, Lawes, CM, Parag, V, Senior, H, Rodgers, A. (2009). Reducing attention deficits after stroke using attention process training: a randomized controlled trial. Stroke, 40(10), 3293–8Google Scholar
Barker-Collo, S, Feigin, VL, Parag, V, Lawes, CMM, Senior, H. (2010). Auckland Stroke Outcomes Study Part 2: Cognition and functional outcomes 5 years poststroke. Neurology, 75, 1608–18.Google Scholar
Black-Schaffer, RM, Osberg, JS. (1990). Return to work after stroke: development of a predictive model. Arch Phys Med Rehabil, 71(5), 285–90.Google Scholar
Bowen, A, Hazelton, C, Pollock, A, Lincoln, NB. (2013). Cognitive rehabilitation for spatial neglect following stroke. Cochrane Database Syst Rev, 7. CD003586. doi:10.1002/14651858.CD003586.pub3.Google Scholar
Bowen, A, Hesketh, A, Patchick, E, Young, A, Davies, L, Vail, A, et al. (2012). Clinical effectiveness, cost effectiveness and service users’ perceptions of early, well-resourced communication therapy following a stroke: a randomised controlled trial (the ACT NoW Study). Health Technol Assess, 16(26), 1160.Google Scholar
Bowen, A, Knapp, P, Gillespie, D, Nicolson, DJ, Vail, A. (2011). Non-pharmacological interventions for perceptual disorders following stroke and other adult-acquired, non-progressive brain injury. Cochrane Database Syst Rev, 4. CD007039.Google Scholar
Brady MC, Ali M, VandenBerg K, Williams J, Williams LR, Abo M, et al. (2020). RELEASE: a protocol for a systematic review based, individual participant data, meta- and network meta-analysis, of complex speech-language therapy interventions for stroke-related aphasia.Aphasiology, 34, (2), 137–57.Google Scholar
Brady, MC, Godwin, J, Kelly, Enderby P, Elders, A, Campbell, P. (2018). Attention control comparisons with SLT for people with aphasia following stroke: methodological concerns raised following a systematic review. Clin Rehabil, 32(10), 1383–95. doi 0269215518780487.Google Scholar
Brady, MC, Kelly, H, Godwin, J, Enderby, P, Campbell, P. (2016). Speech and language therapy for aphasia following stroke. Cochrane Database Syst Rev, 6. CD000425. doi:10.1002/14651858.CD000425.pub4.Google Scholar
Breitenstein, C, Grewe, T, Flöel, A, Ziegler, W, Springer, L, Martus, P, et al., for the FCET2EC study group. (2017). Intensive speech and language therapy in patients with chronic aphasia after stroke: a randomized, open-label, blinded-endpoint, controlled trial in a health-care setting. Lancet, 389(10078), 1528–38.Google Scholar
Burgess, PW, Shallice, T. (1997). The Hayling and Brixton Tests. Bury St. Edmunds: Thames Valley Test Company.Google Scholar
Chung, CSY, Pollock, A, Campbell, T, Durward, BR, Hagen, S. (2013). Cognitive rehabilitation for executive dysfunction in adults with stroke or other adult non-progressive acquired brain damage. Cochrane Database Syst Rev, 4. CD008391. doi:10.1002/14651858.CD008391.pub2.CrossRefGoogle ScholarPubMed
Ciccone N, West D, Cream A, Cartwright J, Rai T, Granger A, et al. (2016) Constraint-induced aphasia therapy (CIAT): a randomised controlled trial in very early stroke rehabilitation. Aphasiology, 30(5), 566–84.Google Scholar
Cicerone, KD, Langenbahn, DM, Braden, C, Malec, JF, Kalmar, K, Fraas, M, et al. (2011). Evidence-based cognitive rehabilitation: updated review of the literature from 2003 through 2008. Arch Phys Med Rehabil, 92, 519–30.Google Scholar
das Nair, R, Cogger, H, Worthington, E, Lincoln, NB. (2016). Cognitive rehabilitation for memory deficits after stroke. Cochrane Database Syst Rev, 9. CD002293. doi:10.1002/14651858.CD002293.pub3.Google Scholar
das Nair, R, Lincoln, N. (2007). Cognitive rehabilitation for memory deficits following stroke. Cochrane Database Syst Rev, 3. CD002293. doi:10.1002/14651858.CD002293.pub2.Google Scholar
David, R, Enderby, P, Bainton, D. (1982). Treatment of acquired aphasia: speech therapists and volunteers compared. J Neurol Neurosurg Psychiatry, 45(11), 957–61.Google Scholar
Dickey, L, Kagan, A, Lindsay, MP, Fang, J, Rowland, A, Black, S. (2010). Incidence and profile of inpatient stroke-induced aphasia in Ontario, Canada. Arch Phys Med Rehabil, 91(2), 196202.Google Scholar
Engelter, ST, Gostynski, M, Papa, S, Frei, M, Born, C, Ajdacic-Gross, V, et al. (2006). Epidemiology of aphasia attributable to first ischemic stroke: incidence, severity, fluency, etiology, and thrombolysis. Stroke, 37(6), 1379–84.Google Scholar
Evans, JJ. (2003). Rehabilitation of executive deficits. In Wilson, BA, ed., Neuropsychological Rehabilitation. Abingdon: Swets and Zeitlinger.Google Scholar
Evans, JJ. (2009). The cognitive group, Part 2: Memory. In Wilson, BA, Gracey, F, Evans, JJ, Bateman, A, eds., Neuropsychological Rehabilitation: Theory, Therapy and Outcomes. Cambridge: Cambridge University Press.Google Scholar
Evans, JJ. (2013). Disorders of memory. In Goldstein, LH, McNeil, JE, eds., Clinical Neuropsychology: A Practical Guide to Assessment and Management for Clinicians. 2nd ed. Chichester: Wiley.Google Scholar
Evans, JJ, Needham, P, Wilson, BA, Brentnall, S. (2003). Which memory impaired people make good use of memory aids? Results of a survey of people with acquired brain injury. J Int Neuropsychol Soc, 9, 925935.Google Scholar
Fong, KNK, Chan, MKL, Ng, PPK, Tsang, MHN, Chow, KKY, Lau, CWL, et al. (2007). The effect of voluntary trunk rotation and half-field eye-patching for patients with unilateral neglect in stroke: a randomized controlled trial. Clin Rehabil, 21, 729–41.Google Scholar
Frassinetti, F, Angeli, V, Meneghello, F, Avanzi, S, Ladavas, E. (2002) Long-lasting amelioration of visuospatial neglect by prism adaptation. Brain, 125, 608–23.Google Scholar
Gialanella, B. (2011) Aphasia assessment and functional outcome prediction in patients with aphasia after stroke. J Neurol, 258(2), 343–9.Google Scholar
Gialanella, B, Prometti, P. (2009). Rehabilitation length of stay in patients suffering from aphasia after stroke. Top Stroke Rehabil, 16(6):437–44.Google Scholar
Gillespie, DC, Bowen, A, Chung, CS. Cockburn, J, Knapp, P, Pollock, A. (2015) Rehabilitation for post-stroke cognitive impairment: an overview of recommendations arising from systematic reviews of current evidence. Clin Rehabil, 29(2), 120–8.Google Scholar
Godecke, E, Rai, T, Cadilhac, DA, Armstrong, E, Middleton, S, Ciccone, N, et al., (2018). Statistical analysis plan (SAP) for the Very Early Rehabilitation in Speech (VERSE) after stroke trial: an international 3-arm clinical trial to determine the effectiveness of early, intensive, prescribed, direct aphasia therapy. Int J Stroke, 13(8), 863–80.Google Scholar
Hoffmann, T, Bennett, S, Koh, CL, McKenna, KT. (2010). Occupational therapy for cognitive impairment in stroke patients. Cochrane Database Syst Rev, 9. CD006430. doi:10.1002/14651858.CD006430.pub2.Google Scholar
Howard, D, Patterson, K, Franklin, S, Orchard-lisle, V, Morton, J. (1985). The facilitation of picture naming in aphasia. Cogn Neuropsychol, 2(1), 4980.Google Scholar
Hurkmans, J, de Bruijn, M, Boonstra, AM, Jonkers, R, Bastiaanse, R, Arendzen, H, et al. (2012). Music in the treatment of neurological language and speech disorders: A systematic review. Aphasiology, 26(1), 119.Google Scholar
Intercollegiate Stroke Working Party. (2016). National Clinical Guideline for Stroke. 5th ed. Royal College of Physicians. Available at: https://www.rcplondon.ac.uk/guidelines-policy/stroke-guidelines. Accessed 24th January 2020.Google Scholar
Jokinen, H, Melkas, S, Ylikoski, R, Pohjasvaara, T, Kaste, M, Erkinjuntti, T, et al. (2015). Post-stroke cognitive impairment is common even after successful clinical recovery. Eur J Neurol, 22, 1288–94.Google Scholar
Krasny-Pacini, A, Chevignard, M, Evans, JJ. (2014). Goal management training for rehabilitation of executive functions: a systematic review of effectiveness in patients with acquired brain injury. Disabil Rehabil, 36, 105–16.Google Scholar
Levine, B, Robertson, IH, Clare, L, Carter, G, Hong, J, Wilson, BA, et al. (2000). Rehabilitation of executive functioning: an experimental-clinical validation of goal management training. J Int Neuropsychol Soc, 6, 299312.Google Scholar
Loetscher, T, Lincoln, NB. (2013). Cognitive rehabilitation for attention deficits following stroke. Cochrane Database Syst Rev, 5. CD002842.Google Scholar
Luauté, J, Halligan, P, Rode, G, Rossetti, Y, Boisson, D. (2006). Visuo-spatial neglect: a systematic review of current interventions and their effectiveness. Neurosci Biobehav Rev, 30(7), 961–82.Google Scholar
Middleton, LE, Lam, B, Fahmi, H, Black, SE, McIlroy, WE, Stuss, DT, et al. (2014). Frequency of domain-specific cognitive impairment in sub-acute and chronic stroke. Neurorehabilitation, 34(2), 305–12.Google Scholar
Mizuno, K, Tsuji, T, Takebayashi, T, Fujiwara, T, Hase, K, Liu, M. (2011). Prism adaptation therapy enhances rehabilitation of stroke patients with unilateral spatial neglect: a randomized, controlled trial. Neurorehabil Neural Repair, 25, 711–20.Google Scholar
National Institute for Health and Care Excellence (NICE). (2013). Stroke rehabilitation: long-term rehabilitation after stroke. Retrieved from www.nice.org.uk/guidance/cg162.Google Scholar
Nouwens, F, de Lau, LM, Visch-Brink, EG, van de Sandt-Koenderman, WM, Lingsma, HF, Goosen, S, et al. (2017). Efficacy of early cognitive-linguistic treatment for aphasia due to stroke: a randomised controlled trial (Rotterdam Aphasia Therapy Study-3). Eur Stroke J, 2(2), 126–36.Google Scholar
Palmer R, Dimairo M, Cooper C, Enderby P, Brady M, Bowen A, Latimer N, Julious S, Cross E, Alshreef A , Harrison M, et al. (2019). Self-managed, computerised speech and language therapy for patients with chronic aphasia post-stroke compared with usual care or attention control (Big CACTUS) : a multicentre, single-blinded, randomised controlled trial. Lancet Neurol, 18(9), 821–33.Google Scholar
Paolucci, S, Matano, A, Bragoni, M, Coiro, P, De Angelis, D, Fusco, FR, et al. (2005). Rehabilitation of left brain-damaged ischemic stroke patients: the role of comprehension language deficits. Cerebrovasc Dis, 20(5), 400–06.Google Scholar
Pedersen, PM, Vinter, K, Olsen, TS. (2004). Aphasia after stroke: type, severity and prognosis. The Copenhagen Aphasia Study. Cerebrovasc Dis, 17(1), 3543.Google Scholar
Pollock, A, Hazelton, C, Henderson, CA, Angilley, J, Dhillon, B, Langhorne, P, et al. (2011). Interventions for visual field defects in patients with stroke. Cochrane Database Syst Rev, 10. CD008388. doi:10.1002/14651858.CD008388.pub2.Google Scholar
Pollock, A, Hazelton, C, Rowe, FJ, Jonuscheit, S, Kernohan, A, Angilley, J, et al. (2019). Interventions for visual field defects in patients with stroke. Cochrane Database Syst Rev, 5. CD008388. doi:10.1002/14651858.CD008388.pub3.Google Scholar
Pulvermuller, F, Neininger, B, Elbert, T, Mohr, B, Rockstroh, B, Koebbel, P, Taub, E. (2001). Constraint-induced therapy of chronic aphasia after stroke. Stroke, 32(7): 1621–6.Google Scholar
Robertson, IH, McMillan, TM, MacLeod, E, Edgeworth, J, Brock, D. (2002). Rehabilitation by limb activation training reduces left-sided motor impairment in unilateral neglect patients: a single-blind randomised control trial. Neuropsychol Rehabil, 12, 439–54.Google Scholar
Rowe, FJ, Wright, D, Brand, D, Jackson, C, Harrison, S, Maan, T, et al. (2013). A prospective profile of visual field loss following stroke: prevalence, type, rehabilitation, and outcome. Biomed Res Int, 2013, 719096.Google Scholar
Sackley, CM, Walker, MF, Burton, CR, Watkins, CL, Mant, J, Roalfe, AK, et al. (2015). An occupational therapy intervention for residents with stroke related disabilities in UK care homes (OTCH): cluster randomised controlled trial. BMJ, 350, h468.Google Scholar
Sarno, MT. (1969). The Functional Communication Profile: Manual of Directions. Vol. 42. New York: Institute of Rehabilitation Medicine, New York University Medical Center.Google Scholar
Seghier, ML, Patel, E, Prejawa, S, Ramsden, S, Selmer, A, Li, L, et al. (2016). The PLORAS database: a data repository for predicting language outcome and recovery after stroke. Neuroimage, 124(Pt B), 1208–12.Google Scholar
Sickert, A, Anders, LC, Munte, TF, Sailer, M. (2014). Constraint-induced aphasia therapy following sub-acute stroke: a single-blind, randomised clinical trial of a modified therapy schedule. J Neurol Neurosurg Psychiatry, 85(1), 51–5.Google Scholar
SIGN. (2010). 118 Management of patients with stroke: rehabilitation, prevention and management of complications, and discharge planning. A national clinical guideline. Edinburgh: Scottish Intercollegiate Guidelines Network. ISBN 978 1 905813 63 6. www.sign.ac.uk/assets/sign118.pdfGoogle Scholar
Stahl, B, Mohr, B, Büscher, V, Dreyer, FR, Lucchese, G, Pulvermüller, F. (2017) Efficacy of intensive aphasia therapy in patients with chronic stroke: a randomised controlled trial. J Neurol Neurosurg Psychiatry, 89, 586–92.Google Scholar
Tate, RL, Perdices, M, McDonald, S, Togher, L, Rosenkoetter, U. (2014). The design, conduct and report of single-case research: resources to improve the quality of the neurorehabilitation literature. Neuropsychol Rehabil, 24, 315–31.Google Scholar
Tatemichi, TK, Desmond, DW, Stern, Y, Paik, M, Sano, M, Bagiella, E. (1994). Cognitive impairment after stroke – frequency, patterns, and relationship to functional abilities. J Neurol Neurosurg Psychiatry, 57, 202–07.Google Scholar
Tunnard, C, Wilson, BA. (2014). Comparison of neuropsychological rehabilitation techniques for unilateral neglect: an ABACADAEAF single-case experimental design. Neuropsychol Rehabil, 24, 382–99.Google Scholar
van der Meulen, I, van de Sandt-Koenderman, ME, Ribbers, GM. (2012). Melodic Intonation Therapy: present controversies and future opportunities. Arch Phys Med Rehabil, 93(1 Suppl), S46–52.Google Scholar
van der Meulen, I, van de Sandt-Koenderman, WM, Heijenbrok-Kal, MH, Visch-Brink, EG, Ribbers, GM. (2014). The efficacy and timing of melodic intonation therapy in subacute aphasia. Neurorehabil Neural Repair, 28(6),3644.Google Scholar
Vataja, R, Pohjasvaara, T, Mäntylä, R, Ylikoski, R, Leppävuori, A, Leskelä, M, et al. (2003). MRI correlates of executive dysfunction in patients with ischaemic stroke. Eur J Neurol, 10, 625–31.Google Scholar
von Cramon, DY, von Cramon, GM, Mai, N. (1991). Problem-solving deficits in brain-injured patients: a therapeutic approach. Neuropsychol Rehabil, 1, 4564.Google Scholar
Wallace, SJ, Worrall, L, Rose, T, Le Dorze, G, Breitenstein, C, Hilari, K, et al. (2019). A core outcome set for aphasia treatment research: the ROMA consensus statement. Int J Stroke, 14(2), 180–5. doi:1747493018806200.Google Scholar
Whitworth, A, Webster, J, Howard, D. (2005). A Cognitive Neuropsychological Approach to Assessment and Intervention in Aphasia: A Clinician’s Guide. Hove: Psychology Press.Google Scholar
Wilson, BA. (2002). Towards a comprehensive model of cognitive rehabilitation. Neuropsychol Rehabil, 12, 97110.Google Scholar
Wilson, BA, Alderman, N, Burgess, PW, Emslie, H, Evans, JJ. (1996). The Behavioural Assessment of Dysexecutive Syndrome. Flempton: Thames Valley Test Company.Google Scholar
Wilssens, I, Vandenborre, D, van Dun, K, Verhoeven, J, Visch-Brink, E, Marien, P. (2015). Constraint-induced aphasia therapy versus intensive semantic treatment in fluent aphasia. Am J Speech Lang Pathol, 24(2), 281–94.Google Scholar
Westerberg, H, Jacobaeus, H, Hirvikoski, T, Clevberger, P, Ostensson, ML, Bartfai, A, et al. (2007). Computerized working memory training after stroke – a pilot study. Brain Inj, 21(1), 21–9.Google Scholar

References

Adkins, DL, Jones, TA. (2005). D-amphetamine enhances skilled reaching after ischemic cortical lesions in rats. Neurosci Lett, 380, 214–18.Google Scholar
Alaverdashvili, M, Lim, DH, Whishaw, IQ. (2007). No improvement by amphetamine on learned non-use, attempts, success or movement in skilled reaching by the rat after motor cortex stroke. Eur J Neurosci, 25, 3442–52.Google Scholar
Albert, ML, Bachman, DL, Morgan, A, Helm-Estabrooks, N. (1988). Pharmacotherapy for aphasia. Neurology, 38, 877–9.Google Scholar
Aroniadou, VA, Teyler, TJ. (1991). The role of NMDA receptors in long-term potentiation (LTP) and depression (LTD) in rat visual cortex. Brain Res, 562, 136–43.Google Scholar
Artola, A, Singer, W. (1989). NMDA receptors and developmental plasticity in visual neocortex. In Collingridge, GL Watkins, JC, eds., The NMDA Receptor. Oxford: Oxford University Press, pp. 153–66.Google Scholar
Bachman, DL, Morgan, A. (1988). The role of pharmacotherapy in the treatment of aphasia. Aphasiology, 3–4, 225–8.Google Scholar
Barbay, S, Zoubina, EV, Dancause, N, Frost, SB, Eisner-Janowicz, I, Stowe, AM, et al. (2006). A single injection of D-amphetamine facilitates improvements in motor training following a focal cortical infarct in squirrel monkeys. Neurorehabil Neural Repair, 20, 455–8.Google Scholar
Blandina, P, Goldfarb, J, Walcott, J, Green, JP. (1991). Serotonergic modulation of the release of endogenous norepinephrine from rat hypothalamic slices. J Pharmacol Exp Ther, 256, 341–7.Google Scholar
Bliss, TV, Collingridge, GL. (1993). A synaptic model of memory: long-term potentiation in the hippocampus. Nature, 361, 31–9.Google Scholar
Boyeson, MG, Callister, TR, Cavazos, JE. (1992a). Biochemical and behavioral effects of a sensorimotor cortex injury in rats pretreated with the noradrenergic neurotoxin DSP-4. BehavNeurosci, 106, 964–73.Google Scholar
Boyeson, MG, Feeney, DM. (1990). Intraventricular norepinephrine facilitates motor recovery following sensorimotor cortex injury. Pharmacol BiochemBehav, 35, 497501.Google Scholar
Boyeson, MG, Harmon, RL. (1993). Effects of trazodone and desipramine on motor recovery in brain-injured rats. Am J Phys Med Rehabil, 72, 286–93.Google Scholar
Boyeson, MG, Harmon, RL, Jones, JL. (1994). Comparative effects of fluoxetine, amitriptyline and serotonin on functional motor recovery after sensorimotor cortex injury. Am J Phys Med Rehabil, 73, 7683.Google Scholar
Boyeson, MG, Krobert, KA, Grade, CM, Scherer, PJ. (1992b). Unilateral, but not bilateral, locus coeruleus lesions facilitate recovery from sensorimotor cortex injury. Pharmacol Biochem Behav, 43, 771–7.Google Scholar
Boyeson, MG, Scherer, PJ, Grade, CM, Krobert, KA. (1993). Unilateral locus coeruleus lesions facilitate motor recovery from cortical injury through supersensitivity mechanisms. Pharmacol Biochem Behav, 44, 297305.Google Scholar
Brailowsky, S, Knight, RT, Efron, R. (1986). Phenytoin increases the severity of cortical hemiplegia in rats. Brain Res, 376, 71–7.Google Scholar
Bröcher, S, Artola, A, Singer, W. (1992). Agonists of cholinergic and noradrenergic receptors facilitate synergistically the induction of long-term potentiation in slices of rat visual cortex. Brain Res, 573, 2736.Google Scholar
Brown, AW, Bjelke, B, Fuxe, K. (2004). Motor response to amphetamine treatment, task-specific training, and limited motor experience in a postacute animal stroke model. Exp Neurol, 190, 102–08.Google Scholar
Burgard, EC, Decker, G, Sarvey, JM. (1989). NMDA receptor antagonists block norepinephrine-induced long- lasting potentiation and long-term potentiation in rat dentate gyrus. Brain Res, 482, 351–5.CrossRefGoogle ScholarPubMed
Burgard, EC, Sarvey, JM. (1990). Muscarinic receptor activation facilitates the induction of long-term potentiation (LTP) in the rat dentate gyrus. Neurosci Lett, 116, 3439.Google Scholar
Bütefisch, CM, Kleiser, R, Körber, B, Müller, K, Wittsack, HJ, Hömberg, V, et al. (2005). Recruitment of contralesional motor cortex in stroke patients with recovery of hand function. Neurology, 64, 1067–9.Google Scholar
Chen, MJ, Sutton, RL, Feeney, DM. (1986). Recovery of function after brain injury in rat and cat: beneficial effects of phenylpropanolamine. Abstracts Soc Neurosci, 12, 881.Google Scholar
Chollet, F, Tardy, J, Albucher, JF, Thalamas, C, Berard, E, Lamy, C, et al. (2011). Fluoxetine for motor recovery after acute ischaemic stroke (FLAME): a randomised placebo-controlled trial. Lancet Neurol, 10, 123–30.Google Scholar
Cohen, BM, Lipinski, JF. (1986). In vivo potencies of antipsychotic drugs in blocking alpha 1 noradrenergic and dopamine D2 receptors: implications for drug mechanisms of action. Life Sci, 39, 2571–80.Google Scholar
Cramer, SC. (2011). An overview of therapies to promote repair of the brain after stroke. Head Neck, 33, (Suppl 1), S57.Google Scholar
Cramer, SC, Nelles, G, Benson, RR, Kaplan, JD, Parker, RA, Kwong, KK, et al. (1997). A functional MRI study of subjects recovered from hemiparetic stroke. Stroke, 28, 2518–27.Google Scholar
Crisostomo, EA, Duncan, PW, Propst, MA, Dawson, DB, Davis, JN. (1988). Evidence that amphetamine with physical therapy promotes recovery of motor function in stroke patients. Ann Neurol, 23, 94–7.Google Scholar
Dahl, D, Sarvey, JM. (1989). Norepinephrine induces pathway-specific long-lasting potentiation and depression in the hippocampal dentate gyrus. Proc Natl Acad Sci USA, 86, 4776–80.CrossRefGoogle ScholarPubMed
Dam, M, Tonin, P, De Boni, A, Pizzolato, G, Casson, S, Ermani, M, et al. (1996). Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy. Stroke, 27, 1211–14.Google Scholar
Delanoy, RL, Tucci, DL, Gold, PE. (1983). Amphetamine effects on long term potentiation in dentate granule cells. Pharmacol Biochem Behav, 18, 137–9.Google Scholar
Dietrich, WD, Alonso, O, Busto, R, Ginsberg, MD. (1990). Influence of amphetamine treatment on somatosensory function of the normal and infarcted rat brain. Stroke, 21 (Suppl. III), III-147-III–150.Google Scholar
Dose, JM, Dhillon, HS, Maki, A, Kraemer, PJ, Prasad, RM. (1997). Lack of delayed effects of amphetamine, methoxamine, and prazosin (adrenergic drugs) on behavioral outcome after lateral fluid percussion brain injury in the rat. J Neurotrauma, 14, 327–37.Google Scholar
Dunbar, GL, Smith, GA, Look, SK, Whalen, RJ. (1989). d-Amphetamine attenuates learning and motor deficits following cortical injury in rats. Abstracts Soc Neurosci, 15, 132.Google Scholar
Dunwiddie, TV, Roberson, NL, Worth, T. (1982). Modulation of long-term potentiation: effects of adrenergic and neuroleptic drugs. Pharmacol Biochem Behav, 17, 1257–64.Google Scholar
El Husseini, N, Goldstein, LB, Peterson, ED, Zhao, X, Pan, W, Olson, D.M, et al. (2012). Depression and antidepressant use after stroke and transient ischemic attack. Stroke, 43, 1609–16.Google Scholar
Enderby, P, Broeckx, J, Hospers, W, Schildermans, F, Deberdt, W. (1994). Effect of piracetam on recovery and rehabilitation after stroke: a double-blind, placebo-controlled study. Clin Neuropharmacol, 17, 320–31.Google Scholar
Feeney, DM. (1991). Pharmacologic modulation of recovery after brain injury: a reconsideration of diaschisis. J Neurol Rehabil, 5, 113–28.Google Scholar
Feeney, DM, Gonzalez, A, Law, WA. (1981). Amphetamine restores locomotor function after motor cortex injury in the rat. Proc West Pharmacol Soc, 24, 1517.Google Scholar
Feeney, DM, Gonzalez, A, Law, WA. (1982). Amphetamine, haloperidol, and experience interact to affect the rate of recovery after motor cortex injury. Science, 217, 855–7.Google Scholar
Feeney, DM, Hovda, DA. (1983). Amphetamine and apomorphine restore tactile placing after motor cortex injury in the cat. Psychopharmacology, 79, 6771.Google Scholar
Feeney, DM, Hovda, DA. (1985). Reinstatement of binocular depth perception by amphetamine and visual experience after visual cortex ablation. Brain Res, 342, 352–6.Google Scholar
Feeney, DM, Westerberg, VS. (1990). Norepinephrine and brain damage: alpha noradrenergic pharmacology alters functional recovery after cortical trauma. Can J Psychol, 44, 233–52.Google Scholar
Fiorelli, M, Blin, J, Bakchine, S, Laplane, D, Baron, JC. (1991). PET studies of cortical diaschisis in patients with motor hemi-neglect. J Neurol Sci, 104, 135–42.Google Scholar
FOCUS Trial Collaboration. (2019). Effects of fluoxetine on functional outcomes after acute stroke (FOCU): a pragmatic, double-blind, randomized, controlled trial. Lancet, 393, 265–74.Google Scholar
Fuxe, K, Ungerstedt, U. (1970). Histochemical, biochemical and functional studies on central monoamine neurons after acute and chronic amphetamine administration. In Costa, E, Garattini, S, eds., Amphetamines and Related Compounds. New York: Raven Press, pp. 257288.Google Scholar
Gladstone, DJ, Danells, CJ, Armesto, A, Mcllroy, WE, Staines, WR, Graham, SJ, et al. (2006). Physiotherapy coupled with dextroamphetamine for motor rehabilitation after hemiparetic stroke: a randomized, double-blind, placbo-controlled trial. Stroke, 37, 179–85.Google Scholar
Gold, PE, Delanoy, RL, Merrin, J. (1984). Modulation of long-term potentiation by peripherally administered amphetamine and epinephrine. Brain Res, 305, 103–07.Google Scholar
Goldstein, LB. (1990). Pharmacology of recovery after stroke. Stroke, 21 (Suppl. III), III-139–III-142.Google Scholar
Goldstein, LB. (1995). Right vs. left sensorimotor cortex suction-ablation in the rat: no difference in beam-walking recovery. Brain Res, 674, 167–70.Google Scholar
Goldstein, LB. (1997). Effects of bilateral and unilateral locus coeruleus lesions on beam-walking recovery after subsequent unilateral sensorimotor cortex suction-ablation in the rat. Restor Neurol Neurosci, 11, 5563.Google Scholar
Goldstein, LB. (1998). Potential effects of common drugs on stroke recovery. Arch Neurol, 55, 454–6.Google Scholar
Goldstein, LB. (2000). Effects of amphetamines and small related molecules on recovery after stroke in animals and man. Neuropharmacology, 39, 852–9.Google Scholar
Goldstein, LB. (2006). Neurotransmitters and motor activity: effects on functional recovery after brain injury. NeuroRx, 3, 451–7.Google Scholar
Goldstein, LB. (2009). Amphetamine trials and tribulations. Stroke, 40 (Suppl. 1), S133S135.Google Scholar
Goldstein, LB, Bullman, S. (1997). Effects of dorsal noradrenergic bundle lesions on recovery after sensorimotor cortex injury. Pharmacol Biochem Behav, 58, 1151–7.Google Scholar
Goldstein, LB, Bullman, S. (1999). Age but not sex affects motor recovery after unilateral sensorimotor cortex suction-ablation in the rat. Restor Neurol Neurosci, 15, 3943.Google Scholar
Goldstein, LB, Bullman, S. (2002). Differential effects of haloperidol and clozapine on motor recovery after sensorimotor cortex injury in the rat. Neurorehabil Neural Repair, 16, 321–5.Google Scholar
Goldstein, LB, Coviello, A, Miller, GD, Davis, JN. (1991). Norepinephrine depletion impairs motor recovery following sensorimotor cortex injury in the rat. Restor Neurol Neurosci, 3, 41–7.Google Scholar
Goldstein, LB, Davis, JN. (1988). Physician prescribing patterns following hospital admission for ischemic cerebrovascular disease. Neurology, 38, 1806–09.Google Scholar
Goldstein, LB, Davis, JN. (1990a). Clonidine impairs recovery of beam-walking in rats. Brain Res, 508, 305–09.Google Scholar
Goldstein, LB, Davis, JN. (1990b). Influence of lesion size and location on amphetamine-facilitated recovery of beam-walking in rats. Behav Neurosci, 104, 318–25.Google Scholar
Goldstein, LB, Davis, J.N. (1990c). Post-lesion practice and amphetamine-facilitated recovery of beam-walking in the rat. Restor Neurol Neurosci, 1, 311–14.Google Scholar
Goldstein, LB, Hasselblad, V, McCrory, DC, Matchar, DB. (1995). Meta-analysis and comparison of randomized trials of endarterectomy for symptomatic carotid stenosis. Neurology, 45 (Suppl 4), A375.Google Scholar
Goldstein, LB, Matchar, DB, Morgenlander, JC, Davis, JN. (1990). Influence of drugs on the recovery of sensorimotor function after stroke. J NeuroloRehabi, 4, 137–44.Google Scholar
Goldstein, LB, Poe, HV, Davis, JN. (1989). An animal model of recovery of function after stroke: Facilitation of recovery by an a2-adrenergic receptor antagonist. Ann Neurol, 26, 157.Google Scholar
Grade, C, Redford, B, Chrostowski, J, Toussaint, L, Blackwell, B. (1998). Methylphenidate in early poststroke recovery: a double-blind, placebo-controlled study. Arch Phys Med Rehabil, 79, 1047–50.Google Scholar
Green, J, Forster, A, Bogle, S, Young, J. (2002). Physiotherapy for patients with mobility problems more than 1 year after stroke: a randomised controlled trial. Lancet, 359, 199203.Google Scholar
Gupta, SR, Mlcoch, AG, Scolaro, C, Moritz, T. (1995). Bromocriptine treatment of nonfluent aphasia. Neurology, 45, 2170–3.Google Scholar
Hernandez, TD, Holling, LC. (1994). Disruption of behavioral recovery by the anti-convulsant phenobarbital. Brain Res, 635, 300–06.Google Scholar
Hernandez, TD, Jones, GH, Schallert, T. (1989). Co-administration of Ro 15–1788 prevents diazepam-induced retardation of recovery of function. Brain Res, 487, 8995.Google Scholar
Hovda, DA, Bailey, B, Montoya, S, Salo, AA, Feeney, DM. (1983). Phentermine accelerates recovery of function after motor cortex injury in rats and cats. FASEB J, 42, 1157.Google Scholar
Hovda, DA, Feeney, DM. (1984). Amphetamine with experience promotes recovery of locomotor function after unilateral frontal cortex injury in the cat. Brain Res, 298, 358–61.Google Scholar
Hovda, DA, Sutton, RL, Feeney, DM. (1987). Recovery of tactile placing after visual cortex ablation in cat: a behavioral and metabolic study of diaschisis. Exp Neurol, 97, 391402.Google Scholar
Hovda, DA, Sutton, RL, Feeney, DM. (1989). Amphetamine-induced recovery of visual cliff performance after bilateral visual cortex ablation in cats: measurements of depth perception thresholds. Behav Neurosci, 103, 574–84.Google Scholar
Huber, W, Willmes, K, Poeck, K, Van Vleymen, B, Deberdt, W. (1997). Piracetam as an adjuvant to language therapy for aphasia: a randomized double-blind placebo-controlled pilot study. Arch Phys Med Rehabil, 78, 245–50.Google Scholar
Hurwitz, BE, Dietrich, WD, McCabe, PM, Watson, BD, Ginsberg, MD, Schneiderman, N. (1989). Amphetamine-accelerated recovery from cortical barrel-field infarction: pharmacological treatment of stroke. In Ginsberg, MD, Dietrich, WD, eds., Cerebrovascular Diseases. The Sixteenth Research (Princeton) Conference. New York: Raven Press, pp. 309318.Google Scholar
Infeld, B, Davis, SM, Lichtenstein, M, Mitchell, PJ, Hopper, JL. (1995). Crossed cerebellar diaschisis and brain recovery after stroke. Stroke, 26, 90–5.Google Scholar
Iriki, A, Pavlides, C, Keller, A, Asanuma, H. (1989). Long-term potentiation in the motor cortex. Science, 245, 1385–7.Google Scholar
Ito, T, Miura, Y, Kadokawa, T. (1988). Effects of physostigmine and scopolamine on long-term potentiation of hippocampal population spikes in rats. Can J Physiol Pharmacol, 66, 1010–16.Google Scholar
Jaspers, RMA, Van Der Sprenkel, JWB, Tulleken, CAF, Cools, AR. (1990). Local as well as remote functional and metabolic changes after focal ischemia in cats. Brain Res Bull, 24, 2332.Google Scholar
Johnson, ML, Roberts, MD, Ross, AR, Witten, CM. (1992). Methylphenidate in stroke patients with depression. Am J Phys Med Rehabil, 71, 239–41.Google Scholar
Jones, TA, Schallert, T. (1992). Subcortical deterioration after cortical damage: effects of diazepam and relation to recovery of function. Behav Brain Res, 51, 113.Google Scholar
Kaplitz, SE. (1975). Withdrawn, apathetic geriatric patients responsive to methylphenidate. J Am Geriatr Soc, 23, 271–6.Google Scholar
Keith, JR, Wu, Y, Epp, JR, Sutherland, RJ. (2007). Fluoxetine and the dentate gyrus: memory, recovery of function, and electrophysiology. Behav Pharmacol, 18, 521–31.Google Scholar
Keller, A, Iriki, A, Asanuma, H. (1990). Identification of neurons producing long-term potentiation in the cat motor cortex: intracellular recordings and labeling. J Comp Neurol, 300, 4760.Google Scholar
Kessler, J, Thiel, A, Karbe, H, Heiss, WD. (2000). Piracetam improves activated blood flow and facilitates rehabilitation of poststroke aphasic patients. Stroke, 31, 2112–16.Google Scholar
Kikuchi, K, Nishino, K, Ohyu, H. (1999). L-DOPS-Accelerated recovery of locomotor function in rats subjected to sensorimotor cortex ablation injury: pharmacobehavioral studies. Tohoku J Exp Med, 188, 203–15.Google Scholar
Kikuchi, K, Nishino, K, Ohyu, H. (2000). Increasing CNS norepinephrine levels by the precursor L-DOPS facilitates beam-walking recovery after sensorimotor cortex ablation in rats. Brain Res, 860, 130–5.Google Scholar
Kline, AE, Chen, MJ, Tso-Olivas, DY, Feeney, DM. (1994). Methylphenidate treatment following ablation-induced hemiplegia in rat: experience during drug action alters effects on recovery of function. Pharmacol Biochem Behav, 48, 773–9.Google Scholar
Kraglund, KL, Mortensen, JK, Damsbo, AG, Modrau, B, Simonsen, SA, Iversen, HK, et al. (2018). Neuroregeneration and Vascular Protection by Citalopram in Acute Ischemic Stroke (TALOS). Stroke, 49(11), 2568–76. doi:10.1161/STROKEAHA.Google Scholar
Kulla, A, Manahan-Vaughan, D. (2002). Modulation by serotonin 5-HT(4) receptors of long-term potentiation and depotentiation in the dentate gyrus of freely moving rats. Cereb Cortex, 12, 150–62.Google Scholar
Larsson, M, Ervik, M, Lundborg, P, Sundh, V, Svanborg, A. (1988). Comparison between methylphenidate and placebo as adjuvant in care and rehabilitation of geriatric patients. Comp Gerontol, 2, 53–9.Google Scholar
Lenzi, GL, Frackowiak, RSJ, Jones, T. (1982). Cerebral oxygen metabolism and blood flow in human cerebral infarction. J Cereb Blood Flow Metab, 2, 321–35.Google Scholar
Lipsey, JR, Pearlson, GD, Robinson, RG, Rao, K, Price, TR. (1984). Nortriptyline treatment of post-stroke depression: a double-blind study. Lancet, 1, 297300.Google Scholar
Maling, HM, Acheson, GH. (1946). Righting and other postural activity in low-decerebrate and in spinal cats after d-amphetamine. J Neurophysiol, 9, 379–86.Google Scholar
Manahan-Vaughan, D, Kulla, A. (2003). Regulation of depotentiation and long-term potentiation in the dentate gyrus of freely moving rats by dopamine D2-like receptors. Cereb Cortex, 13, 123–35.Google Scholar
Martin, WRW, Raichle, ME. (1983). Cerebellar blood flow and metabolism in cerebral hemisphere infarction. Ann Neurol, 14, 168–76.Google Scholar
Martinsson, L, Eksborg, S, Wahlgren, NG. (2003). Intensive early physiotherapy combined with dexamphetamine treatment in severe stroke: a randomized, controlled pilot study. Cerebrovasc Dis, 16, 338–45.Google Scholar
Martinsson, L, Hardemark, H, Eksborg, S. (2007). Amphetamines for improving recovery after stroke. Cochrane Database Syst Rev, 1. CD002090.Google Scholar
Marzo, A, Bai, J, Otani, S. (2009). Neuroplasticity regulation by noradrenaline in mammalian brain. Curr Neuropharmacol, 7, 286–95.Google Scholar
Masotto, C., Apud, J. A., & Racagni, G. (1985). Neurochemical studies on GABAergic and aminergic systems in the rat brain following acute and chronic piracetam administration. Pharmacol Res Commun, 17, 749–72.Google Scholar
Mead, GE, Hsieh, CF, Hackett, M. (2013). Selective serotonin reuptake inhibitors for stroke recovery. JAMA, 310, 1066–7.Google Scholar
Meyer, PM, Horel, JA, Meyer, DR. (1963). Effects of dl-amphetamine upon placing responses in neodecorticate cats. J Comp PhysiolPsychol, 56, 402–04.Google Scholar
Nishino, K, Sasaki, T, Takahashi, K, Chiba, M, Ito, T. (2001). The norepinephrine precursor L-threo-3, 4-dihydroxyphenylserine facilitates motor recovery in chronic stroke patients. J Clin Neurosci, 8, 547–50.Google Scholar
Olpe, HR, Karlsson, G. (1990). The effects of baclofen and two GABA B-receptor antagonists on long-term potentiation. Naunyn Schmiedeberg Arch Pharmacol, 342, 194–7.Google Scholar
Peroutka, SJ, U’Pritchard, DC, Greenberg, DA, Snyder, SH. (1977). Neuroleptic drug interactions with norepinephrine alpha receptor binding sites in rat brain. Neuropharmacology, 16, 549–56.Google Scholar
Prasad, RM, Dose, JM, Dhillon, HS, Carbary, T, Kraemer, PJ. (1995). Amphetamine affects the behavioral outcome of lateral fluid percussion brain injury in the rat. Restor Neurol Neurosci, 9, 6575.Google Scholar
Ramic, M, Emerick, AJ, Bollnow, MR, O’Brien, TE, Tsai, SY, Kartje, GL. (2006). Axonal plasticity is associated with motor recovery following amphetamine treatment combined with rehabilitation after brain injury in the adult rat. Brain Res, 1111, 176–86.Google Scholar
Reding, MJ, Orto, LA, Winter, SW, Fortuna, IM, Di Ponte, P, McDowell, FH. (1986). Antidepressant therapy after stroke. A double-blind trial. Arch Neurol, 43, 763–5.Google Scholar
Reding, MJ, Solomon, B, Borucki, SJ. (1995). Effect of dextroamphetamine on motor recovery after stroke. Neurology, 45 (Suppl. 4), A222.Google Scholar
Roffler-Tarlov, S, Schildkraut, JJ, Draskoczy, PR. (1973). Effects of acute and chronic administration of desmethylimipramine on the content of norepinephrine and other monamines in the rat brain. Biochem Pharmacol, 22, 2923–6.Google Scholar
Sabe, L, Salvarezza, F, Cuerva, AG, Leiguarda, R, Starkstein, S. (1995). A randomized, double-blind, placebo-controlled study of bromocriptine in nonfluent aphasia. Neurology, 45, 2272–4.Google Scholar
Santarelli, L, Saxe, M, Gross, C, Surget, A, Battaglia, F, Dulawa, S, et al. (2003). Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science, 301, 805–09.Google Scholar
Satoh, M, Ishihara, K, Iwama, T, Takagi, H. (1986). Aniracetam augments, and midazolam inhibits, the long-term potentiation in guinea-pig hippocampal slices. Neurosci Lett, 68, 216–20.Google Scholar
Schallert, T, Hernandez, TD, Barth, TM. (1986). Recovery of function after brain damage: Severe and chronic disruption by diazepam. Brain Res, 379, 104–11.Google Scholar
Schallert, T, Jones, TA, Weaver, MS, Shapiro, LE, Crippens, D, Fulton, R. (1992). Pharmacologic and anatomic considerations in recovery of function. Phys Med Rehabil, 6, 375–93.Google Scholar
Schmanke, TD, Avery, RA, Barth, TM. (1996). The effects of amphetamine on recovery of function after cortical damage in the rat depend on the behavioral requirements of the task. J Neurotrauma, 13, 293307.Google Scholar
Sonde, L, Nordström, M, Nilsson, C-G, Lökk, J, Viitanen, M. (2001). A double-blind placebo-controlled study of the effects of amphetamine and physiotherapy after stroke. Cerebrovasc Dis, 12, 253–7.Google Scholar
Stanton, PK, Sarvey, JM. (1985). Blockade of norepinephrine-induced long-lasting potentiation in the hippocampal dentate gyrus by an inhibitor of protein synthesis. Brain Res, 361, 276–83.Google Scholar
Stroemer, RP, Kent, TA, Hulsebosch, CE. (1994). Amphetamines permanently promote recovery following cortical infarction. Abstracts Soci Neurosci, 20, 186.Google Scholar
Stroemer, RP, Kent, TA, Hulsebosch, CE. (1995). Neocortical neural sprouting, synaptogenesis, and behavioral recovery after neocortical infarction in rats. Stroke, 26, 2135–44.Google Scholar
Sutton, RL, Feeney, DM. (1992). α-Noradrenergic agonists and antagonists affect recovery and maintenance of beam-walking ability after sensorimotor cortex ablation in the rat. Restor Neurol Neurosci, 4, 111.Google Scholar
Sutton, RL, Hovda, DA, Feeney, DM. (1989). Amphetamine accelerates recovery of locomotor function following bilateral frontal cortex ablation in cats. Behav Neurosci, 103, 837–41.Google Scholar
Tanaka, M, Kondo, S, Hirai, S. Ishiguro, K, Ishihara, T, Morimatsu, M. (1992). Crossed cerebellar diaschisis accompanied by hemiataxia: a PET study. J Neurol Neurosurg Psychiatry, 55, 121–5.Google Scholar
Theodore, DR, Meier-Ruge, W, Abraham, J. (1992). Microvascular morphometry in primate diaschisis. Microvasc Res, 43, 147–55.Google Scholar
Treig, T, Werner, C, Sachse, M, Hesse, S. (2003). No benefit from D-amphetamine when added to physiotherapy after stroke: a randomized, placebo-controlled study. Clin Rehabil, 17, 590–9.Google Scholar
Troisi, E, Paolucci, S, Silvestrini, M, Matteis, M, Vernieri, F, Grasso, MG., et al (2002). Prognostic factors in stroke rehabilitation: the possible role of pharmacological treatment. Acta Neurol Scand, 105, 100–06.Google Scholar
Van Hasselt, P. (1973). Effect of butyrophenones on motor function in rats after recovery from brain damage. Neuropharmacology, 12, 245–7.Google Scholar
Wade, DT, Collen, FM, Robb, GF, Warlow, CP. (1992). Physiotherapy intervention late after stroke and mobility. Br Med J, 304, 609–13.Google Scholar
Walker-Batson, D, Curtis, S, Natarajan, R, Ford, J, Dronkers, N, Salmeron, E, et al. (2001). A double-blind, placebo-controlled study of the use of amphetamine in the treatment of aphasia. Stroke, 32, 2093–8.Google Scholar
Walker-Batson, D, Smith, P, Curtis, S, Unwin, H, Greenlee, R. (1995). Amphetamine paired with physical therapy accelerates motor recovery after stroke – further evidence. Stroke, 26, 2254–9.Google Scholar
Weaver, MS, Chen, MJ, Westerberg, VS, Feeney, DM. (1988). Locus coeruleus lesions facilitate recovery of locomotor function after sensorimotor cortex contusion in the rat. Abstracts Soc Neurosci, 14, 405.Google Scholar
Wigstrom, H, Gustafsson, B. (1985). Facilitation of hippocampal long-lasting potentiation by GABA antagonists. Acta Physiol Scand, 125, 159–72.Google Scholar
Williams, S, Johnston, D. (1988). Muscarinic depression of long-term potentiation in CA3 hippocampal neurons. Science, 242, 84–7.Google Scholar
Wilson, MS, Hamm, RJ. (2002). Effects of fluoxetine on the 5-HT1A receptor and recovery of cognitive function after traumatic brain injury in rats. Am J Phys Med Rehabil, 81, 364–72.Google Scholar

References

Antal, A, Alekseichuk, I, Bikson, M, Brockmöller, J, Brunoni, AR, Chen, R, et al. (2017). Low intensity transcranial electric stimulation: safety, ethical, legal regulatory and application guidelines. Clin Neurophysiol, 128(9), 17741809.Google Scholar
Barker, AT, Jalinous, R, Freeston, IL. (1985). Non-invasive magnetic stimulation of the human motor cortex. Lancet, 1, 1106–07.Google Scholar
Bath, PM, Lee, HS, Everton, LF. (2018). Swallowing therapy for dysphagia in acute and subacute stroke. Cochrane Database Syst Rev, 10. CD000323. doi:10.1002/14651858.CD000323.pub3.Google Scholar
Bikson, M, Grossman, P, Thomas, C, Zannou, AL, Jiang, J, Adnan, T, et al. (2016). Safety of transcranial direct current stimulation: evidence based update 2016. Brain Stimul, 9(5), 641–61.Google Scholar
Boggio, PS, Nunes, A, Rigonatti, SP. (2007). Repeated sessions of non-invasive brain DC stimulation is associated with motor function improvement in stroke patients. Restor Neurol Neurosci, 25, 123–9.Google Scholar
Bolognini, N, Pascual-Leone, A, Fregni, F. (2009). Using non-invasive brain stimulation to augment motor training-induced plasticity. J Neuroeng Rehabil, 6(8).Google Scholar
Brunoni, AR, Nitsche, MA, Bolognini, N, Bikson, M, Wagner, T, Merabet, L, et al. (2012). Clinical research with transcranial direct current stimulation (tDCS): challenges and future directions. Brain Stimul, 5(3), 175–95.Google Scholar
Cabrera, LY, Evans, EL, Hamilton, RH. (2014). Ethics of the electrified mind: defining issues and perspectives on the principled use of brain stimulation in medical research and clinical care. Brain Topogr, 27(1), 3345.Google Scholar
Chaieb, L, Antal, A, Pisoni, A, Saiote, C, Opitz, A, Ambrus, GG, et al. (2014). Safety of 5 kHz tACS. Brain Stimul, 7(1), 92–6.Google Scholar
Chang, MC, Kim, DY, Park, DH. (2015). Enhancement of cortical excitability and lower limb motor function in patients with stroke by transcranial direct current stimulation. Brain Stimul, 8(3), 561–6.Google Scholar
Chiang, CF, Lin, MT, Hsiao, MY, Yeh, YC, Liang, YC, Wang, TG (2018). Comparative efficacy of noninvasive neurostimulation therapies for acute and subacute poststroke dysphagia: a systematic review and network meta-analysis. Arch Phys Med Rehabil, 100(4), 739–50. doi:10.1016/j.apmr.2018.09.117.Google Scholar
Dmochowski, JP, Datta, A, Bikson, M, Su, Y, Parra, LC. (2011). Optimized multi-electrode stimulation increases focality and intensity at target. J Neural Eng, 8(4), 046011.Google Scholar
Elsner, B, Kugler, J, Pohl, M, Mehrholz, J. (2015). Transcranial direct current stimulation (tDCS) for improving aphasia in patients with aphasia after stroke. Cochrane Database Syst Rev, 5. CD009760.Google Scholar
Elsner, B, Kugler, J, Pohl, M, Mehrholz, J. (2016a). Transcranial direct current stimulation (tDCS) for improving activities of daily living, and physical and cognitive functioning, in people after stroke. Cochrane Database Syst Rev, 3. CD009645. doi:10.1002/14651858.CD009645.pub3.Google Scholar
Elsner, B, Kugler, J, Pohl, M, Mehrholz, J. (2016b). Transcranial direct current stimulation for improving spasticity after stroke: a systematic review with meta-analysis. J Rehabil Med, 48(7), 565–70.Google Scholar
Fitz, NS, Reiner, PB. (2015). The challenge of crafting policy for do-it-yourself brain stimulation. J Med Ethics, 41(5), 410–12.CrossRefGoogle ScholarPubMed
Giordano, J, Bikson, M, Kappenman, ES, Clark, VP, Coslett, HB, Hamblin, MR, et al. (2017). Mechanisms and effects of transcranial direct current stimulation. Dose Response, 15(1), 1559325816685467. doi:10.1177/1559325816685467. eCollection 2017 Jan-Mar.Google Scholar
Guleyupoglu, B, Schestatsky, P, Edwards, D, Fregni, F, Bikson, M. (2013). Classification of methods in transcranial electrical stimulation (tES) and evolving strategy from historical approaches to contemporary innovations. J Neurosci Methods, 219(2), 297311.Google Scholar
Hao, Z, Wang, D, Zeng, Y, Lui, M. (2013). Repetitive transcranial magnetic stimulation for improving function after stroke. Cochrane Database Syst Rev, 5. CD008862.Google Scholar
Kang, EK, Baek, MJ, Kim, S, Paik, NJ. (2009). Non-invasive cortical stimulation improves post-stroke attention decline. Restor Neurol Neurosci, 27(6), 645–50.Google Scholar
Kazuta, T, Takeda, K, Osu, R, Tanaka, S, Oishi, A, Kondo, K, Liu, M. (2017). Transcranial direct current stimulation improves audioverbal memory in stroke patients. Am J Phys Med Rehabil, 96(8), 565–71.Google Scholar
Kim, JH, Kim, DW, Chang, WH, Kim, YH, Kim, K, Im, CH. (2014). Inconsistent outcomes of transcranial direct current stimulation may originate from anatomical differences among individuals: electric field simulation using individual MRI data. Neurosci Lett, 564, 610.Google Scholar
Koyama, S, Tanaka, S., Tanabe, S, Sadato, N. (2015). Dual-hemisphere transcranial direct current stimulation over primary motor cortex enhances consolidation of a ballistic thumb movement. Neurosci Lett, 588, 4953. doi:20.1016/j.neulet.2014.11.043. epub 2014 Nov 28.Google Scholar
Krause, B, Marquez-Ruiz, J, Cohen Kadosh, R. (2013). The effect of transcranial direct current stimulation: a role for cortical excitation/inhibition balance? Front Hum Neurosci, 7, 602.Google Scholar
Kuo, HI, Bikson, M, Datta, A, Minhas, P, Paulus, W, Kuo, M. F, et al. (2013). Comparing cortical plasticity induced by conventional and high-definition 4 x 1 ring tDCS: a neurophysiological study. Brain Stimul, 6(4), 644–8.Google Scholar
Lang, N, Siebner, HR, Ward, NS. Lee, L, Nitsche, MA. Paulus, W., Rothwell, JC, et al. (2005). How does transcranial DC stimulation of the primary motor cortex alter regional neuronal activity in the human brain? Eur J Neurosci, 22(2), 495504.CrossRefGoogle ScholarPubMed
Li, Y, Fan, J, Yang, J, He, C, Li, S. (2018). Effects of repetitive transcranial magnetic stimulation on walking and balance function after stroke: a systematic review and meta-analysis. Am J Phys Med Rehabil, 97(11), 773–81.Google Scholar
Li, Y, Qu, Y, Yuan, M, Du, T. (2015). Low-frequency repetitive transcranial magnetic stimulation for patients with aphasia after stroke: a meta-analysis. J Rehabil Med, 47, 675–81.Google Scholar
Liebetanz, D, Koch, R, Mayenfels, S, Konig, F, Paulus, W, Nitsche, MA. (2009). Safety limits of cathodal transcranial direct current stimulation in rats. Clin Neurophysiol, 120, 1161–7.Google Scholar
Lu, H, Zhang, T, Wen, M, Sun, L. (2015). Impact of repetitive transcranial magnetic stimulation on post-stroke dysmnesia and the role of BDNF Val66Met SNP. Med Sci Monit, 21, 761–8. doi:10.12659/MSM.892337.Google Scholar
Machii, K, Cohen, D, Ramos-Estebanez, C, Pascual-Leone, A. (2006). Safety of rTMS to non-motor cortical areas in healthy participants and patients. Clin Neurophysiol, 117(2), 455–71.Google Scholar
Marquez, J, van Vliet, P, McElduff, P, Lagopoulos, J, Parsons, M. (2015). Transcranial direct current stimulation (tDCS): does it have merit in stroke rehabilitation? A systematic review. Int J Stroke, 10(3), 306–16.Google Scholar
Marshall, L, Binder, S. (2013). Contribution of transcranial oscillatory stimulation to research on neural networks: an emphasis on hippocampo-neocortical rhythms. Front Hum Neurosci, 7, 614.Google Scholar
McClintock, SM, Reti, IM, Carpenter, LL, McDonald, WM, Dubin, M, Taylor, SF, et al.; National Network of Depression Centers rTMS Task Group; American Psychiatric Association Council on Research Task Force on Novel Biomarkers and Treatments. (2018). Consensus recommendations for the Clinical Application of Repetitive Transcranial Magnetic Stimulation (rTMS) in the treatment of depression. J Clin Psychiatry, 79(1). pii: 16cs10905. doi:10.4088/JCP.16cs10905.Google Scholar
McCreery, DB, Agnew, WF, Yuen, TG, and Bullara, L. (1990). Charge density and charge per phase as cofactors in neural injury induced by electrical stimulation. IEEE Trans Biomed Eng, 37, 9961001.Google Scholar
Meinzer, M, Darkow, R, Lindenberg, R, Flöel, A. (2016). Electrical stimulation of the motor cortex enhances treatment outcome in post-stroke aphasia. Brain, 139(Pt 4), 1152–63.Google Scholar
Moliadze, V, Antal, A, Paulus, W. (2010a). Boosting brain excitability by transcranial high frequency stimulation in the ripple range. J Physiol, 588(24), 48914904.Google Scholar
Moliadze, V, Antal, A, Paulus, W. (2010b). Electrode-distance dependent after-effects of transcranial direct and random noise stimulation with extracephalic reference electrodes. Clin Neurophysiol, 121, 2165–71.Google Scholar
Nitsche, MA, Cohen, L, Wassermann, EM, Priori, A, Lang, N, Antal, A, et al. (2008). Transcranial direct current stimulation: state of the art 2008. Brain Stimul, 1, 206–23.Google Scholar
Nitsche, MA, Nitsche, MS, Klein, CC. (2003). Level of action of cathodal DC polarisation induced inhibition of the human motor cortex. Clin Neurophysiol, 114, 600–04.Google Scholar
Nitsche, MA, Paulus, W. (2000). Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation. J Physiol, 527(3), 633–9.Google Scholar
Paulus, W, Peterchev, AV, Ridding, M. (2013). Transcranial electric and magnetic stimulation: technique and paradigms. Handb Clin Neurol, 116, 329–42.Google Scholar
Peterchev, AV, Wagner, TA, Miranda, PC, Nitsche, MA, Paulus, W, Lisanby, SH, et al. (2012). Fundamentals of transcranial electric and magnetic stimulation dose: definition, selection, and reporting practices. Brain Stimul, 5(4), 435–53.Google Scholar
Priori, A, Hallett, M, Rothwell, JC. (2009). Repetitive transcranial magnetic stimulation or transcranial direct current stimulation? Brain Stimul, 2(4), 241–5.Google Scholar
Radman, T, Ramos, RL, Brumberg, JC, Bikson, M. (2009). Role of cortical cell type and morphology in subthreshold and suprathreshold uniform electric field stimulation in vitro. Brain Stimul, 2(4), 215–28.Google Scholar
Reato, D, Rahman, A, Bikson, M, Parra, LC. (2013). Effects of weak transcranial alternating current stimulation on brain activity – a review of known mechanisms from animal studies. Front Hum Neurosci, 7, 687.Google Scholar
Redfearn, JWT, Lippold, OC, Constain, R. (1964). A preliminary account of the clinical effects of polarizing the brain in certain psychiatric disorders. Br J Psychiatry, 110, 773–85.Google Scholar
Romero, JR, Anschel, D, Sparing, R, Gangitano, M, Pascual-Leone, A. (2002). Subthreshold low frequency repetitive transcranial magnetic stimulation selectively decreases facilitation in the motor cortex. Clin Neurophysiol, 113, 101–07.Google Scholar
Rossi, S, Hallett, M, Rossini, PM, Pascual-Leone, A; Safety of TMS Consensus Group. (2009). Safety, ethical considerations and application guidelines for the use of transcranial magnetic stimulation in clinical practice and research. Clin Neurophysiol, 120, 2008–39.Google Scholar
Saiote, C, Turi, Z, Paulus, W, Antal, A. (2013). Combining functional magnetic resonance imaging with transcranial electrical stimulation. Front Hum Neurosci, 7, 435.Google Scholar
Salazar, APS, Vaz, PG, Marchese, RR, Stein, C, Pinto, C, Pagnussat, AS. (2018). Noninvasive brain stimulation improves hemispatial neglect after stroke: a systematic review and meta-analysis. Arch Phys Med Rehabil, 99(2), 355–66.e1.Google Scholar
Schlaug, G, Renga, V, Nair, DG. (2008). Transcranial direct current stimulation in stroke recovery. Arch Neurol, 65(12), 1571–6.Google Scholar
Shaker, HA, Sawan, SAE, Fahmy, EM, Ismail, RS, Elrahman, SAEA. (2018). Effect of transcranial direct current stimulation on cognitive function in stroke patients. Egypt J Neurol Psychiatr Neurosurg, 54(1), 32. doi:10.1186/s41983-018-0037-8.Google Scholar
Shen, X, Liu, M, Cheng, Y, Jia, C, Pan, X, Gou, Q, et al. (2017). Repetitive transcranial magnetic stimulation for the treatment of post-stroke depression: a systematic review and meta-analysis of randomized controlled clinical trials. J Affect Disord, 211, 6574.Google Scholar
Silvanto, J, Pascual-Leone, A. (2008). State-dependency of transcranial magnetic stimulation. Brain Topogr, 21(1), 110.Google Scholar
Smith, DV, Clithero, JA. (2009). Manipulating executive function with transcranial direct current stimulation. Front Integr Neurosci, 3, 26.Google Scholar
Sohn, MK, Jee, SJ, Kim, YW. (2013). Effect of transcranial direct current stimulation on postural stability and lower extremity strength in hemiplegic stroke patients. Ann Rehabil Med, 37(6), 759–65.Google Scholar
Spielmann, K, van de Sandt-Koenderman, WME, Heijenbrok-Kal, MH, Ribbers, GM. (2018). Transcranial direct current stimulation does not improve language outcome in subacute poststroke aphasia. Stroke, 49(4), 1018–20.Google Scholar
Tahtis, V, Kaski, D, Seemungal, BM. (2014). The effect of single session bi-cephalic transcranial direct current stimulation on gait performance in sub-acute stroke: a pilot study. Restor Neurol Neurosci, 32(4), 527–32.Google Scholar
Talelli, P, Wallace, A, Dileone, M, Hoad, D, Cheeran, B, Oliver, R, et al. (2012). Theta burst stimulation in the rehabilitation of the upper limb: a semirandomized, placebo-controlled trial in chronic stroke patients. Neurorehabil Neural Repair, 26(8), 976–87.Google Scholar
Tanaka, S, Hanakawa, T, Honda, M, Watanabe, K. (2009). Enhancement of pinch force in the lower leg by anodal transcranial direct current stimulation. Exp Brain Res, 196(3), 459–65.Google Scholar
Tanaka, S, Takeda, K, Otaka, Y, Kita, K, Osu, R, Honda, M, et al. (2011). Single session of transcranial direct current stimulation transiently increases knee extensor force in patients with hemiparetic stroke. Neurorehabil Neural Repair, 25(6), 565–9.Google Scholar
Terney, D, Chaieb, L, Moliadze, V, Antal, A, Paulus, W. (2008). Increasing Human brain excitability by transcranial high-frequency random noise stimulation. J Neurosci, 28, 14147–55.Google Scholar
Valiengo, LC, Goulart, AC, de Oliveira, JF, Benseñor, IM, Lotufo, PA, Brunoni, AR. (2017). Transcranial direct current stimulation for the treatment of post-stroke depression: results from a randomised, sham-controlled, double-blinded trial. J Neurol Neurosurg Psychiatry, 8(2), 170–5.Google Scholar
Wagner, T, Fregni, F, Fecteau, S, Grodzinsky, A, Zahn, M, Pascual-Leone, A. (2007a). Transcranial direct current stimulation: a computer-based human model study. Neuroimage, 35, 1113–24.Google Scholar
Wagner, T, Valero-Cabre, A, Pascual-Leone, A. (2007b). Noninvasive human brain stimulation. Ann Rev Biomed Eng, 9, 527–65.Google Scholar
Wolters, A, Sandbrink, F, Schlottmann, A, Kunesch, E, Stefan, K, Cohen, LG, et al. (2003). A temporally asymmetric Hebbian rule governing plasticity in the human motor cortex. J Neurophysiol, 89(5), 2339–45.Google Scholar
Yun, GJ, Chun, MH, Kim, BR. (2015). The effects of transcranial direct-current stimulation on cognition in stroke patients. J Stroke, 17(3), 354–8.Google Scholar
Zhang, L, Xing, G, Fan, Y, Guo, Z, Chen, H, Mu, Q. (2017). Short- and long-term effects of repetitive transcranial magnetic stimulation on upper limb motor function after stroke: a systematic review and meta-analysis. Clin Rehabil, 31(9), 1137–53.sssGoogle Scholar

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