15 results
A Shuffle Theorem for Paths Under Any Line
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- Jonah Blasiak, Mark Haiman, Jennifer Morse, Anna Pun, George H. Seelinger
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- Journal:
- Forum of Mathematics, Pi / Volume 11 / 2023
- Published online by Cambridge University Press:
- 22 February 2023, e5
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We generalize the shuffle theorem and its $(km,kn)$ version, as conjectured by Haglund et al. and Bergeron et al. and proven by Carlsson and Mellit, and Mellit, respectively. In our version the $(km,kn)$ Dyck paths on the combinatorial side are replaced by lattice paths lying under a line segment whose x and y intercepts need not be integers, and the algebraic side is given either by a Schiffmann algebra operator formula or an equivalent explicit raising operator formula. We derive our combinatorial identity as the polynomial truncation of an identity of infinite series of $\operatorname {\mathrm {GL}}_{l}$ characters, expressed in terms of infinite series versions of LLT polynomials. The series identity in question follows from a Cauchy identity for nonsymmetric Hall–Littlewood polynomials.
A Proof of the Extended Delta Conjecture
- Part of
- Jonah Blasiak, Mark Haiman, Jennifer Morse, Anna Pun, George H. Seelinger
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- Journal:
- Forum of Mathematics, Pi / Volume 11 / 2023
- Published online by Cambridge University Press:
- 22 February 2023, e6
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We prove the extended delta conjecture of Haglund, Remmel and Wilson, a combinatorial formula for $\Delta _{h_l}\Delta ' _{e_k} e_{n}$ , where $\Delta ' _{e_k}$ and $\Delta _{h_l}$ are Macdonald eigenoperators and $e_n$ is an elementary symmetric function. We actually prove a stronger identity of infinite series of $\operatorname {\mathrm {GL}}_m$ characters expressed in terms of LLT series. This is achieved through new results in the theory of the Schiffmann algebra and its action on the algebra of symmetric functions.
3110 The association between components of the Life’s Simple Seven and incident end stage renal disease in the Southern Community Cohort Study
- Mindy Pike, Cassianne Robinson-Cohen, Jennifer Morse, Thomas G. Stewart, William J. Blot, T. Alp Ikizler, Loren Lipworth
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- Journal:
- Journal of Clinical and Translational Science / Volume 3 / Issue s1 / March 2019
- Published online by Cambridge University Press:
- 26 March 2019, p. 55
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OBJECTIVES/SPECIFIC AIMS: The Life’s Simple 7 (LS7) metric was created by the American Heart Association with the goal of educating the public on seven modifiable factors that contribute to heart health. While it is well documented that these ideal health behaviors lower risk of cardiovascular disease (CVD) in the general population, the association between the LS7 ideal health metrics and end stage renal disease (ESRD) risk has not been examined in a lower socioeconomic population at high risk for both ESRD and CVD. Our objective is to examine the association between the LS7 score and incident ESRD in a cohort of white and black men and women in the southeastern US, where rates of CVD and ESRD are high. METHODS/STUDY POPULATION: The Southern Community Cohort Study recruited ~86,000 low-income blacks and whites in the southeastern US (2002-2009). Utilizing a nested case-control design, our analysis included 1628 incident cases of ESRD identified via linkage of the cohort with the United States Renal Data System (USRDS) from January 1, 2002 to March 31, 2015. Controls (n = 4884) were individually matched 3:1 with ESRD cases based on age, sex, and race. Demographic, medical, and lifestyle information were obtained via baseline questionnaire. The AHA definitions for ideal health were used for non-smoking (never or quit >12 months), body mass index (BMI<25kg/m2) and physical activity (>75 min/week of vigorous physical activity or >150min/week of moderate/vigorous activity). Modified definitions were used for consuming a healthy diet [Healthy Eating Index (HEI10) score>70] and for blood pressure, fasting plasma glucose, and total cholesterol, based on self-reported no history of diagnosis of hypertension, diabetes, and hypercholesterolemia, respectively. The number of ideal health parameters were summed to generate the LS7 score, which ranged from 0-7 with higher scores indicating more ideal health. Adjusted odds ratios (95% confidence intervals) for incident ESRD associated with LS7 score were calculated using conditional logistic regression models, adjusting for income and education. The SCCS ESRD case-cohort dataset will be available by TS 2019 and analyses will be completed to adjust for baseline estimated glomerular filtration rate (eGFR) as a marker of kidney function and to examine whether eGFR modifies the relationship between LS7 and incident ESRD. RESULTS/ANTICIPATED RESULTS: At baseline, mean age was 54 years, 55% (3600) of participants were women, and 87% (5656) were black. A total of 58% (943) of ESRD cases were non-smokers compared to 54% (2633) of controls. ESRD cases had higher prevalence of BMI>25 kg/m2 (81% vs. 74%), hypertension (84% vs. 59%), hypercholesterolemia (48% vs. 34%), and diabetes (66% vs. 22%) compared to controls. A total of 18% (839) of controls and 12% (194) of ESRD cases met ideal exercise recommendations, and 20% of either cases (302) or controls (916) had a HEI10 score above 70. The median LS7 score for controls and ESRD cases was 3 and 2, respectively, and 17% (983) of participants had a low score (0-1) while 2% (105) met 6 or 7 ideal health metrics. Higher LS7 score was associated with lower odds of ESRD (P-trend<0.001). Participants with LS7 score >3 (above median) had 75% reduced odds of ESRD (OR 0.25; 95% CI 0.22, 0.29) compared to those with a score of 2 or less. DISCUSSION/SIGNIFICANCE OF IMPACT: In the SCCS population, the presence of any 3 or more ideal health behaviors is associated with reduced odds of developing ESRD. The components of the LS7 represent important modifiable risk factors that may be targets for future interventions driven by the patient. The attributable risk due to each factor is needed to dissect which ideal behaviors are the most beneficial.
Contributors
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- By Mitchell Aboulafia, Frederick Adams, Marilyn McCord Adams, Robert M. Adams, Laird Addis, James W. Allard, David Allison, William P. Alston, Karl Ameriks, C. Anthony Anderson, David Leech Anderson, Lanier Anderson, Roger Ariew, David Armstrong, Denis G. Arnold, E. J. Ashworth, Margaret Atherton, Robin Attfield, Bruce Aune, Edward Wilson Averill, Jody Azzouni, Kent Bach, Andrew Bailey, Lynne Rudder Baker, Thomas R. Baldwin, Jon Barwise, George Bealer, William Bechtel, Lawrence C. Becker, Mark A. Bedau, Ernst Behler, José A. Benardete, Ermanno Bencivenga, Jan Berg, Michael Bergmann, Robert L. Bernasconi, Sven Bernecker, Bernard Berofsky, Rod Bertolet, Charles J. Beyer, Christian Beyer, Joseph Bien, Joseph Bien, Peg Birmingham, Ivan Boh, James Bohman, Daniel Bonevac, Laurence BonJour, William J. Bouwsma, Raymond D. Bradley, Myles Brand, Richard B. Brandt, Michael E. Bratman, Stephen E. Braude, Daniel Breazeale, Angela Breitenbach, Jason Bridges, David O. Brink, Gordon G. Brittan, Justin Broackes, Dan W. Brock, Aaron Bronfman, Jeffrey E. Brower, Bartosz Brozek, Anthony Brueckner, Jeffrey Bub, Lara Buchak, Otavio Bueno, Ann E. Bumpus, Robert W. Burch, John Burgess, Arthur W. Burks, Panayot Butchvarov, Robert E. Butts, Marina Bykova, Patrick Byrne, David Carr, Noël Carroll, Edward S. Casey, Victor Caston, Victor Caston, Albert Casullo, Robert L. Causey, Alan K. L. Chan, Ruth Chang, Deen K. Chatterjee, Andrew Chignell, Roderick M. Chisholm, Kelly J. Clark, E. J. Coffman, Robin Collins, Brian P. Copenhaver, John Corcoran, John Cottingham, Roger Crisp, Frederick J. Crosson, Antonio S. Cua, Phillip D. Cummins, Martin Curd, Adam Cureton, Andrew Cutrofello, Stephen Darwall, Paul Sheldon Davies, Wayne A. Davis, Timothy Joseph Day, Claudio de Almeida, Mario De Caro, Mario De Caro, John Deigh, C. F. Delaney, Daniel C. Dennett, Michael R. DePaul, Michael Detlefsen, Daniel Trent Devereux, Philip E. Devine, John M. Dillon, Martin C. Dillon, Robert DiSalle, Mary Domski, Alan Donagan, Paul Draper, Fred Dretske, Mircea Dumitru, Wilhelm Dupré, Gerald Dworkin, John Earman, Ellery Eells, Catherine Z. Elgin, Berent Enç, Ronald P. Endicott, Edward Erwin, John Etchemendy, C. Stephen Evans, Susan L. Feagin, Solomon Feferman, Richard Feldman, Arthur Fine, Maurice A. Finocchiaro, William FitzPatrick, Richard E. Flathman, Gvozden Flego, Richard Foley, Graeme Forbes, Rainer Forst, Malcolm R. Forster, Daniel Fouke, Patrick Francken, Samuel Freeman, Elizabeth Fricker, Miranda Fricker, Michael Friedman, Michael Fuerstein, Richard A. Fumerton, Alan Gabbey, Pieranna Garavaso, Daniel Garber, Jorge L. A. Garcia, Robert K. Garcia, Don Garrett, Philip Gasper, Gerald Gaus, Berys Gaut, Bernard Gert, Roger F. Gibson, Cody Gilmore, Carl Ginet, Alan H. Goldman, Alvin I. Goldman, Alfonso Gömez-Lobo, Lenn E. Goodman, Robert M. Gordon, Stefan Gosepath, Jorge J. E. Gracia, Daniel W. Graham, George A. Graham, Peter J. Graham, Richard E. Grandy, I. Grattan-Guinness, John Greco, Philip T. Grier, Nicholas Griffin, Nicholas Griffin, David A. Griffiths, Paul J. Griffiths, Stephen R. Grimm, Charles L. Griswold, Charles B. Guignon, Pete A. Y. Gunter, Dimitri Gutas, Gary Gutting, Paul Guyer, Kwame Gyekye, Oscar A. Haac, Raul Hakli, Raul Hakli, Michael Hallett, Edward C. Halper, Jean Hampton, R. James Hankinson, K. R. Hanley, Russell Hardin, Robert M. Harnish, William Harper, David Harrah, Kevin Hart, Ali Hasan, William Hasker, John Haugeland, Roger Hausheer, William Heald, Peter Heath, Richard Heck, John F. Heil, Vincent F. Hendricks, Stephen Hetherington, Francis Heylighen, Kathleen Marie Higgins, Risto Hilpinen, Harold T. Hodes, Joshua Hoffman, Alan Holland, Robert L. Holmes, Richard Holton, Brad W. Hooker, Terence E. Horgan, Tamara Horowitz, Paul Horwich, Vittorio Hösle, Paul Hoβfeld, Daniel Howard-Snyder, Frances Howard-Snyder, Anne Hudson, Deal W. Hudson, Carl A. Huffman, David L. Hull, Patricia Huntington, Thomas Hurka, Paul Hurley, Rosalind Hursthouse, Guillermo Hurtado, Ronald E. Hustwit, Sarah Hutton, Jonathan Jenkins Ichikawa, Harry A. Ide, David Ingram, Philip J. Ivanhoe, Alfred L. Ivry, Frank Jackson, Dale Jacquette, Joseph Jedwab, Richard Jeffrey, David Alan Johnson, Edward Johnson, Mark D. Jordan, Richard Joyce, Hwa Yol Jung, Robert Hillary Kane, Tomis Kapitan, Jacquelyn Ann K. Kegley, James A. Keller, Ralph Kennedy, Sergei Khoruzhii, Jaegwon Kim, Yersu Kim, Nathan L. King, Patricia Kitcher, Peter D. Klein, E. D. Klemke, Virginia Klenk, George L. Kline, Christian Klotz, Simo Knuuttila, Joseph J. Kockelmans, Konstantin Kolenda, Sebastian Tomasz Kołodziejczyk, Isaac Kramnick, Richard Kraut, Fred Kroon, Manfred Kuehn, Steven T. Kuhn, Henry E. Kyburg, John Lachs, Jennifer Lackey, Stephen E. Lahey, Andrea Lavazza, Thomas H. Leahey, Joo Heung Lee, Keith Lehrer, Dorothy Leland, Noah M. Lemos, Ernest LePore, Sarah-Jane Leslie, Isaac Levi, Andrew Levine, Alan E. Lewis, Daniel E. Little, Shu-hsien Liu, Shu-hsien Liu, Alan K. L. Chan, Brian Loar, Lawrence B. Lombard, John Longeway, Dominic McIver Lopes, Michael J. Loux, E. J. Lowe, Steven Luper, Eugene C. Luschei, William G. Lycan, David Lyons, David Macarthur, Danielle Macbeth, Scott MacDonald, Jacob L. Mackey, Louis H. Mackey, Penelope Mackie, Edward H. Madden, Penelope Maddy, G. B. Madison, Bernd Magnus, Pekka Mäkelä, Rudolf A. Makkreel, David Manley, William E. Mann (W.E.M.), Vladimir Marchenkov, Peter Markie, Jean-Pierre Marquis, Ausonio Marras, Mike W. Martin, A. P. Martinich, William L. McBride, David McCabe, Storrs McCall, Hugh J. McCann, Robert N. McCauley, John J. McDermott, Sarah McGrath, Ralph McInerny, Daniel J. McKaughan, Thomas McKay, Michael McKinsey, Brian P. McLaughlin, Ernan McMullin, Anthonie Meijers, Jack W. Meiland, William Jason Melanson, Alfred R. Mele, Joseph R. Mendola, Christopher Menzel, Michael J. Meyer, Christian B. Miller, David W. Miller, Peter Millican, Robert N. Minor, Phillip Mitsis, James A. Montmarquet, Michael S. Moore, Tim Moore, Benjamin Morison, Donald R. Morrison, Stephen J. Morse, Paul K. Moser, Alexander P. D. Mourelatos, Ian Mueller, James Bernard Murphy, Mark C. Murphy, Steven Nadler, Jan Narveson, Alan Nelson, Jerome Neu, Samuel Newlands, Kai Nielsen, Ilkka Niiniluoto, Carlos G. Noreña, Calvin G. Normore, David Fate Norton, Nikolaj Nottelmann, Donald Nute, David S. Oderberg, Steve Odin, Michael O’Rourke, Willard G. Oxtoby, Heinz Paetzold, George S. Pappas, Anthony J. Parel, Lydia Patton, R. P. Peerenboom, Francis Jeffry Pelletier, Adriaan T. Peperzak, Derk Pereboom, Jaroslav Peregrin, Glen Pettigrove, Philip Pettit, Edmund L. Pincoffs, Andrew Pinsent, Robert B. Pippin, Alvin Plantinga, Louis P. Pojman, Richard H. Popkin, John F. Post, Carl J. Posy, William J. Prior, Richard Purtill, Michael Quante, Philip L. Quinn, Philip L. Quinn, Elizabeth S. Radcliffe, Diana Raffman, Gerard Raulet, Stephen L. Read, Andrews Reath, Andrew Reisner, Nicholas Rescher, Henry S. Richardson, Robert C. Richardson, Thomas Ricketts, Wayne D. Riggs, Mark Roberts, Robert C. Roberts, Luke Robinson, Alexander Rosenberg, Gary Rosenkranz, Bernice Glatzer Rosenthal, Adina L. Roskies, William L. Rowe, T. M. Rudavsky, Michael Ruse, Bruce Russell, Lilly-Marlene Russow, Dan Ryder, R. M. Sainsbury, Joseph Salerno, Nathan Salmon, Wesley C. Salmon, Constantine Sandis, David H. Sanford, Marco Santambrogio, David Sapire, Ruth A. Saunders, Geoffrey Sayre-McCord, Charles Sayward, James P. Scanlan, Richard Schacht, Tamar Schapiro, Frederick F. Schmitt, Jerome B. Schneewind, Calvin O. Schrag, Alan D. Schrift, George F. Schumm, Jean-Loup Seban, David N. Sedley, Kenneth Seeskin, Krister Segerberg, Charlene Haddock Seigfried, Dennis M. Senchuk, James F. Sennett, William Lad Sessions, Stewart Shapiro, Tommie Shelby, Donald W. Sherburne, Christopher Shields, Roger A. Shiner, Sydney Shoemaker, Robert K. Shope, Kwong-loi Shun, Wilfried Sieg, A. John Simmons, Robert L. Simon, Marcus G. Singer, Georgette Sinkler, Walter Sinnott-Armstrong, Matti T. Sintonen, Lawrence Sklar, Brian Skyrms, Robert C. Sleigh, Michael Anthony Slote, Hans Sluga, Barry Smith, Michael Smith, Robin Smith, Robert Sokolowski, Robert C. Solomon, Marta Soniewicka, Philip Soper, Ernest Sosa, Nicholas Southwood, Paul Vincent Spade, T. L. S. Sprigge, Eric O. Springsted, George J. Stack, Rebecca Stangl, Jason Stanley, Florian Steinberger, Sören Stenlund, Christopher Stephens, James P. Sterba, Josef Stern, Matthias Steup, M. A. Stewart, Leopold Stubenberg, Edith Dudley Sulla, Frederick Suppe, Jere Paul Surber, David George Sussman, Sigrún Svavarsdóttir, Zeno G. Swijtink, Richard Swinburne, Charles C. Taliaferro, Robert B. Talisse, John Tasioulas, Paul Teller, Larry S. Temkin, Mark Textor, H. S. Thayer, Peter Thielke, Alan Thomas, Amie L. Thomasson, Katherine Thomson-Jones, Joshua C. Thurow, Vzalerie Tiberius, Terrence N. Tice, Paul Tidman, Mark C. Timmons, William Tolhurst, James E. Tomberlin, Rosemarie Tong, Lawrence Torcello, Kelly Trogdon, J. D. Trout, Robert E. Tully, Raimo Tuomela, John Turri, Martin M. Tweedale, Thomas Uebel, Jennifer Uleman, James Van Cleve, Harry van der Linden, Peter van Inwagen, Bryan W. Van Norden, René van Woudenberg, Donald Phillip Verene, Samantha Vice, Thomas Vinci, Donald Wayne Viney, Barbara Von Eckardt, Peter B. M. Vranas, Steven J. Wagner, William J. Wainwright, Paul E. Walker, Robert E. Wall, Craig Walton, Douglas Walton, Eric Watkins, Richard A. Watson, Michael V. Wedin, Rudolph H. Weingartner, Paul Weirich, Paul J. Weithman, Carl Wellman, Howard Wettstein, Samuel C. Wheeler, Stephen A. White, Jennifer Whiting, Edward R. Wierenga, Michael Williams, Fred Wilson, W. Kent Wilson, Kenneth P. Winkler, John F. Wippel, Jan Woleński, Allan B. Wolter, Nicholas P. Wolterstorff, Rega Wood, W. Jay Wood, Paul Woodruff, Alison Wylie, Gideon Yaffe, Takashi Yagisawa, Yutaka Yamamoto, Keith E. Yandell, Xiaomei Yang, Dean Zimmerman, Günter Zoller, Catherine Zuckert, Michael Zuckert, Jack A. Zupko (J.A.Z.)
- Edited by Robert Audi, University of Notre Dame, Indiana
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- The Cambridge Dictionary of Philosophy
- Published online:
- 05 August 2015
- Print publication:
- 27 April 2015, pp ix-xxx
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Pittsburgh Registry of Infant Multiplets (PRIM): An Update
- Elizabeth A. Jenkins, Brion S. Maher, Mary L. Marazita, Ralph E. Tarter, Jennifer B. Ganger, Margaret Watt-Morse, Michael M. Vanyukov
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- Journal:
- Twin Research and Human Genetics / Volume 9 / Issue 6 / 01 December 2006
- Published online by Cambridge University Press:
- 21 February 2012, pp. 1006-1008
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This article is an updated review of the Pittsburgh Registry of Infant Multiplets including recruitment methods, data collection, and results of pilot studies conducted in this registry. The main goal of the registry is to study psychological development. The risk for behavior disorders including substance use disorders, as well as language development and dental health are among research targets. Pilot data on the heritability of minor physical anomalies and neuropsychological characteristics (Continuous Performance Test) are reported.
Pittsburgh Registry of Infant Multiplets (PRIM)
- Melissa Strassberg, Katherine Peters, Mary Marazita, Jennifer Ganger, Margaret Watt-Morse, Lenn Murrelle, Ralph Tarter, Michael Vanyukov
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- Journal:
- Twin Research / Volume 5 / Issue 5 / 01 October 2002
- Published online by Cambridge University Press:
- 21 February 2012, pp. 499-501
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This paper describes the Pittsburgh Registry of Infant Multiplets (PRIM; Pittsburgh, Pennsylvania), the results of pilot research conducted in this registry, and the plans for future studies. The main focus of the registry is on psychological development and the risk for behavioral disorders. Particularly, characteristics associated with antisociality and the risk for substance use disorders (e.g., aggressivity, hyperactiv-ity/impulsivity), as well as language development and other traits (e.g., dental health) are among the research targets.
A comparison of the frequencies of risk factors for depression in older black and white participants in a study of indicated prevention
- Roy Sriwattanakomen, Jesse McPherron, Jamie Chatman, Jennifer Q. Morse, Lynn M. Martire, Jordan F. Karp, Patricia R. Houck, Salem Bensasi, Jill Houle, Jacqueline A. Stack, Mattie Woods, Bruce Block, Stephen B. Thomas, Sandra Quinn, Charles F. Reynolds III
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- Journal:
- International Psychogeriatrics / Volume 22 / Issue 8 / December 2010
- Published online by Cambridge University Press:
- 15 September 2010, pp. 1240-1247
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Background: To compare the frequencies of risk factors, we describe risks for depression as a function of race among consecutively admitted participants in a randomized clinical trial of indicated depression prevention in later life.
Methods: Seventy-two black and 143 white participants were screened for risk factors for depression.
Results: Black participants were more likely to have fewer years of education and lower household income. They were more likely to be obese, live alone, experience functional disability, have a history of alcohol and drug abuse, and have lower scores on the Mini-mental State Examination and the Executive Interview (EXIT). White participants were not found to have greater prevalence or higher mean score on any risk factor. On average, black participants experienced approximately one more risk factor than white participants (t(213) = 3.32, p = 0.0011).
Conclusions: In our sample, black participants had higher frequencies of eight risk factors for depression and a greater mean number of risk factors compared to white participants.
Alone? Percieved social support and chronic interpersonal difficulties in suicidal elders
- Katrin E. Harrison, Alexandre Y. Dombrovski, Jennifer Q. Morse, Patricia Houck, Maryann Schlernitzauer, Charles F. Reynolds III, Katalin Szanto
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- Journal:
- International Psychogeriatrics / Volume 22 / Issue 3 / May 2010
- Published online by Cambridge University Press:
- 15 December 2009, pp. 445-454
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Background: Social networks may protect depressed elders against suicidal behavior. However, conflict in important relationships may undermine the sense of social support, potentially negating the protective effects. Thus, we investigated the role of chronic interpersonal difficulties and perceived social support in depressed elders with and without suicidal thoughts and attempts.
Methods: 106 individuals aged 60 years and older participated in this cross-sectional, case-control study. They were placed in three groups: suicidal depressed, non-suicidal depressed and non-depressed. Following a detailed clinical characterization, we assessed perceived social support (Interpersonal Support Evaluation List), and chronic interpersonal difficulties (Inventory of Interpersonal Problems). Using general linear models, we explored the relationship between suicidal thoughts/attempts, social support, and chronic interpersonal difficulties. We also examined whether lower perceived social support explained the relationship between chronic interpersonal difficulties and suicidal thoughts/attempts.
Results: Suicidal depressed elders reported the lowest levels of perceived social support (belonging, tangible support, and self-esteem) and higher levels of chronic interpersonal difficulties (struggle against others and interpersonal hostility), compared to both non-suicidal depressed and non-depressed elders. The relationship between chronic interpersonal difficulties and suicidal behavior was partially explained by low perceived social support.
Conclusions: The experience of strong affects, interpersonal struggle, and hostility in relationships may undermine the sense of social support in depressed elders, possibly leading them to contemplate or attempt suicide. Depressed elders with a history of interpersonal difficulties need to be carefully monitored for suicidal behavior.
Psychosocial care of the elderly
- from Psychology, health and illness
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- By Jennifer Q. Morse, Western Psychiatric Institute and Clinic, Charles F. Reynolds, Western Psychiatric Institute and Clinic
- Edited by Susan Ayers, University of Sussex, Andrew Baum, University of Pittsburgh, Chris McManus, Stanton Newman, Kenneth Wallston, John Weinman, Robert West
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- Cambridge Handbook of Psychology, Health and Medicine
- Published online:
- 18 December 2014
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- 23 August 2007, pp 383-389
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Summary
Mood disorders are among the most significant and often overlooked disorders in later life (Consensus Development Panel of the Depression and Bipolar Support Alliance, 2003). Because there is relatively little research on late-life bipolar disorder, this chapter will focus on depression. Depression is the most frequently diagnosed psychiatric disorder in late life (Verhey & Honig, 1997), particularly among the chronically or acutely medically ill, those in residential facilities, or community dwellers who have recently been bereaved or assumed caregiving roles (Koenig et al., 1997). The prevalence of major depression in community samples ranges from 1% to 5% (Pahkala et al., 1995) but clinically significant depressive symptoms occur more frequently (Verhey & Honig, 1997).
Barriers to effective treatment
One of the biggest barriers to effective treatment of late-life depression may be under-recognition by older adults, their families and their physicians. Late-life depression is significantly under-diagnosed (Mulsant & Ganguli, 1999), particularly in primary care settings (Harman et al., 2001), the healthcare setting used most often by older adults (Unutzer et al., 1999). Many older adults and their physicians assume that low energy, loss of interest and somatic symptoms are part of being old or physically ill, rather than symptoms of depression (Karel & Hinrichsen, 2000) (see ‘Ageing and health behaviour’). Sleep disturbance, failure to care for oneself, withdrawal from social activities, unexplained somatic complaints and hopelessness may be important clinical clues for depression (Gallo et al., 1997).
Rationality Means Being Willing to Say You're Sorry
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- By Jennifer Roback Morse, Stanford University's Hoover Institution
- Edited by Ellen Frankel Paul, Bowling Green State University, Ohio, Fred D. Miller, Jr, Bowling Green State University, Ohio, Jeffrey Paul, Bowling Green State University, Ohio
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- Personal Identity
- Published online:
- 05 July 2014
- Print publication:
- 04 July 2005, pp 204-225
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Summary
I. Introduction
This essay examines the problem of repentance and apology. What is so powerful about the three-word utterance, “I am sorry?” People who feel offended spend time and energy demanding an apology from the offender. People who have given offense often seem to have difficulty giving an apology. I want to ask two basic questions. What does a person really want when he asks for an apology? Why do people so often find it difficult to give an apology?
These questions may not seem to have anything to do with the issue of personal identity. But personal identity is relevant to repentance because one common difficulty with apologizing is that the person is reluctant to admit wrongdoing. The offender is willing to disrupt a relationship, bear costs himself and impose costs on others, rather than admit he did something wrong. Likewise, the victim is infuriated by the offender's failure to say, “I am sorry,” with sufficient sincerity. These are very curious behaviors. I believe that one explanation for these curious behaviors lies in a particular kind of self-understanding: the person identifies himself with his preferences and the behaviors that flow from them. In other words, the unrepentant soul has his own theory of personal identity, quite apart from anything any philosopher might have to say about it. The unrepentant person believes he is his preferences, and that he is entitled to the behavior that flows from those preferences.
RATIONALITY MEANS BEING WILLING TO SAY YOU'RE SORRY
- Jennifer Roback Morse
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- Journal:
- Social Philosophy and Policy / Volume 22 / Issue 2 / July 2005
- Published online by Cambridge University Press:
- 15 June 2005, pp. 204-225
- Print publication:
- July 2005
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What does a person really want when he asks for an apology? Why do people so often find it difficult to give an apology? Repentance is relevant to personal identity because the unrepentant soul has his own theory of personal identity. The unrepentant person believes he is his preference, and that he is entitled to the behavior that flows from those preferences. This fact can explain why people are so often reluctant to admit wrongdoing, why people place so much importance upon receiving an apology and other behaviors that would be otherwise inexplicable. The unrepentant person uses something akin to a naive economic theory of human behavior. The naive version of homo economicus, or economic man, can never truly be sorry for anything, and as a result, will be almost impossible to live with. A person who identifies himself too closely with his preferences will bring misery to himself and those around him.
No Families, No Freedom: Human Flourishing in a Free Society
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- By Jennifer Roback Morse, Stanford University
- Edited by Ellen Frankel Paul, Bowling Green State University, Ohio, Fred D. Miller, Bowling Green State University, Ohio, Jeffrey Paul, Bowling Green State University, Ohio
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- Book:
- Human Flourishing
- Published online:
- 05 October 2013
- Print publication:
- 28 January 1999, pp 290-314
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Summary
INTRODUCTION
This essay has one simple theme: the family does a very important job that no other institution can do. What is that job? Inside a family, helpless babies are transformed from being self-centered bundles of impulses, desires, and emotions to being adult people capable of social behavior of all kinds. Why is this job important? The family teaches the ability to trust, cooperate, and self-restrain. Neither the free market nor self-governing political institutions can survive unless the vast majority of the population possesses these skills. Why is the family uniquely situated to teach these skills and the values that go with them? People develop these qualities in their children as a side effect of loving them. What does this have to do with a free society? Contracts and free political institutions, the foundational structures of a free society, require these attributes that only families can inculcate. Without loving families, no society can long govern itself, for the family teaches the skills of individual self-governance.
There are, of course, many competing visions of what might loosely be called a free society. At the libertarian end of the spectrum are advocates of a “night-watchman state,” a government that performs only the minimal functions of providing national defense, police protection, and a legal system to enforce contracts. A more conservative vision of a free society would allow the government a greater role for inculcating and enforcing moral norms.
Learning From Biological Systems: Novel Routes to Biomimetic Synthesis of Ordered Silica Structures
- Jennifer N. Chal, Katsuhiko Shimizu, Yan Zhou, Sean C. Christiansen, Bradley F. Chmelka, Timothy J. Deming, Galen D. Stucky, Daniel E. Morse
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- Journal:
- MRS Online Proceedings Library Archive / Volume 599 / 1999
- Published online by Cambridge University Press:
- 10 February 2011, 239
- Print publication:
- 1999
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Biological systems have evolved mechanisms that precisely control inorganic structures on both the micro- and nanoscale, operating at ambient pressures and temperatures. In both the calcium carbonate, calcium phosphate and silicon dioxide utilizing organisms, proteins and polysaccharides have been found to play integral roles in the organization of these biominerals[1–3]. The organic constituents generally have been thought to act as direct templates or modulators for the deposition of the particular mineral. We have explored the synthesis and structural control of silica by the marine sponge, Tethya aurantia. Needles of amorphous silica comprise the skeletal system of this organism, representing 75% of the dry weight of the organism. These glassy needles, called spicules, are 2 mm in length and 30 μn in width[4,5]. We have characterized the structure, genetics and functions of the proteins that form an occluded axial filament within each silica spicule. Based on our discovery, a unique structure-directing catalytic mechanism exhibited by these protein filaments, and the structural determinants responsible for the catalytic activity, we have designed novel block copolypeptides that catalyze and spatially direct he condensation of silicon alkoxides to form organized silica structures ranging from transparent spheres to lath-like structures at ambient pressure, low temperature and neutral pH.
No Families, No Freedom: Human Flourishing in a Free Society
- Jennifer Roback Morse
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- Journal:
- Social Philosophy and Policy / Volume 16 / Issue 1 / Winter 1999
- Published online by Cambridge University Press:
- 13 January 2009, pp. 290-314
- Print publication:
- Winter 1999
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This essay has one simple theme: the family does a very important job that no other institution can do. What is that job? Inside a family, helpless babies are transformed from being self-centered bundles of impulses, desires, and emotions to being adult people capable of social behavior of all kinds. Why is this job important? The family teaches the ability to trust, cooperate, and self-restrain. Neither the free market nor selfgoverning political institutions can survive unless the vast majority of the population possesses these skills. Why is the family uniquely situated to teach these skills and the values that go with them? People develop these qualities in their children as a side effect of loving them. What does this have to do with a free society? Contracts and free political institutions, the foundational structures of a free society, require these attributes that only families can inculcate. Without loving families, no society can long govern itself, for the family teaches the skills of individual self-governance.
Who is Rational Economic Man?*
- Jennifer Roback Morse
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- Journal:
- Social Philosophy and Policy / Volume 14 / Issue 1 / Winter 1997
- Published online by Cambridge University Press:
- 13 January 2009, pp. 179-206
- Print publication:
- Winter 1997
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There is, in Sarajevo, a man who comes out into the streets each day and plays his cello on the sidewalk. He does this at the same time each day, no matter how much shooting or shelling is going on, no matter how great the danger to himself. He describes himself as having decided to take a stand for beauty in the face of horror. Can the rational choice paradigm, as currently practiced in the various disciplines of economics, philosophy, political science, and law, offer an account of this man's decision and his behavior?
This admirable man seems to be a rebuke to the philosophies of calculated self-interest. Can we offer some account of his behavior, without descending into the tautological claim that he did what he did because he wanted to? Can we offer some insight into his wants that will make him intelligible? And not only intelligible, but can we account for him in a way that highlights his admirability, rather than suggesting that he is in some way an aberration, or perhaps even a fool?
There is a deep disorder within the human condition. All of the essays in the present volume point to this fact in one way or another. Some characterize the disorder as a conflict between virtue and self-interest. Others point to the dichotomy between the individual and other persons as being the source of the tension between morality and self-interest. Some of the essays attempt to resolve the tension by collapsing the two categories into each other.