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10 - CMOS nanowire biosensing systems
- from Part II - Biosensors
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- By Monika Weber, Yale University, Jason M. Criscione, Yale University, Xuexin Duan, Tianjin University, Tarek M. Fahmy, Yale University, Jason Park, Yale University, Nitin K. Rajan, Yale University, David A. Routenberg, Yale University, Erin Steenblock, Yale University, Eric Stern, Yale University, Aleksandar Vacic, Yale University, Mark A. Reed, Yale University
- Edited by Sandro Carrara, École Polytechnique Fédérale de Lausanne, Krzysztof Iniewski
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- Book:
- Handbook of Bioelectronics
- Published online:
- 05 September 2015
- Print publication:
- 06 August 2015, pp 122-136
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- Chapter
- Export citation
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Summary
Introduction
Lowering the costs of healthcare and increasing its accessibility is a critical need of today’s society. Miniaturized electronic sensors are a possible way to both improve healthcare and lower the cost of medical diagnostics. Their small size and portability can lead to integration into personalized diagnostics tools and emergency care. In addition, faster, smaller and more efficient sensors can greatly impact chemical and biological safety.
The rapid progress demonstrated in the computer industry and in genomics is stirring interest for growth and applications in healthcare and safety. The relentless progress and developments in microfabrication predicted by Moore’s law, which forecast that the number of transistors on an integrated circuit would double every two years, has until now been continually producing faster, cheaper, and smaller consumer electronics. An analogous exponential growth in DNA sequencing is even faster than Moore’s law. Ten years ago, it would have taken many months to sequence a human genome. Today, the same task can be completed within one day. This impressive progress is possible owing to innovative applications of microfabrication technologies. If this can be applied to healthcare, it could stimulate a similar evolution, with applications such as early stage detection of biological infection outbreaks and chemical hazards, which could mitigate epidemics tremendously.