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Correlations between Personality Structure and Adrenocortical Excretion Patterns in MZ Twins*

Published online by Cambridge University Press:  01 August 2014

H. M. Fox ,
S. Gifford ,
A. F. Valenstein  and
B. J. Murawski
H. M. Fox*
Affiliation:
Medical Clinics, Peter Bent Brigham Hospital, and Dept. of Psychiatry, Harvard Medical School, Boston, Mass.
S. Gifford
Affiliation:
Medical Clinics, Peter Bent Brigham Hospital, and Dept. of Psychiatry, Harvard Medical School, Boston, Mass.
A. F. Valenstein
Affiliation:
Medical Clinics, Peter Bent Brigham Hospital, and Dept. of Psychiatry, Harvard Medical School, Boston, Mass.
B. J. Murawski
Affiliation:
Medical Clinics, Peter Bent Brigham Hospital, and Dept. of Psychiatry, Harvard Medical School, Boston, Mass.
*
Peter Bent Brigham Hospital, 721 Huntington Avenue, Boston, Mass. 02115, USA

Extract

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Twenty-one pairs of healthy MZ twins, all males 18-21 years of age, have been studied for possible correlations between individual personality characteristics and relatively constant patterns of pituitary-adrenocortical functioning. Subjects were studied by means of psychiatric interviews, Rorschach and other psychological tests, and 35 24-hour urine collections for 17-hydroxycorticosteroid (17OHCS) and 17-ketosteroid (17KS) determinations.

Our previous observations have been reported, both on these healthy male volunteers (Fox et al, 1961 and 1965) and on various clinical syndromes (Rizzo et al, 1954; Fox et al, 1958; Gifford and Gunderson, 1970). Our cumulative clinical impressions suggested that high levels of 17OHCS excretion are found in individuals with an intense need for close personal relationships, or with an equally intense need to defend themselves against emotional involvement, by active forms of avoidance and denial. Low 17OHCS levels were found in individuals who were more effectively defended against emotional intimacy by well-organized neurotic defenses, with some isolation, constriction of affect or less conscious awareness of conflict.

In studying twins, however, an unusual pattern of high 17KS and low 17OHCS compelled us to pay more attention to the significance of 17KS levels. High 17KS excretion patterns were found in energetic, ambitious individuals, with strong aggressive drives or equally strong defenses against them. Individuals with low 17KS levels were overcon trolled, with limited drive-endowment and widespread inhibitions of impulse and action.

Type
Session 8 - Twin Studies in Metabolism and Endocrinology
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 19 , Issue 1-2 , April 1970 , pp. 132 - 134
Copyright
Copyright © The International Society for Twin Studies 1970

Footnotes

*

Presented (in part), Annual Meeting, American Psychosomatic Society, Boston, Mass., March 29, 1968. The original more detailed version appeared in the Journal of Psychosomatic Research, 14: 71-79, 1970.

References

Burt, C.B. (1958). The inheritance of mental ability. Amer. Psychol., 13: 1–15.CrossRefGoogle Scholar
Fox, H. M., Murawski, B.J., Thorn, G. W., Gray, S.J. (1958). Urinary 17-hydroxycorticoid and uropepsin levels with psychological data: a three-year study of one subject. Arch. Intern. Med. (Chicago), 101: 859–871.Google Scholar
- - Bartholomay, A. F., Gifford, S. (1961). Adrenal steroid excretion patterns in eighteen healthy subjects. Tentative correlations with personality structure. Psychosom. Med., 23: 33–40.Google Scholar
Fox, H. M., Gifford, S., Valenstein, A. F., Murawski, B. J. (1965). Psychophysiology of monozygotic male twins. Arch. Gen. Psychiat. (Chicago), 12: 490–500.Google Scholar
Gifford, S., Gunderson, J. G. (1970). Cushing's disease as a psychosomatic disorder: a selective review of the clinical and experimental literature and a report often cases. Perspect. Biol. Med., 13: 169–221.Google Scholar
Osborne, R. H., Degeorge, F. V. (1959). Genetic Basis of Morphological Variation: an Evaluation and Application of the Twin Study Method. Harvard University Press, Cambridge.Google Scholar
Rizzo, N. D., Fox, H. M., Laidlaw, J. C., Thorn, G. W. (1964). Concurrent observations of behavior changes and of adrenocortical variations in a cyclothymic patient during a period of twelve months. Ann. Intern. Med., 41: 798–815.Google Scholar
Tanner, J. M., Healy, M. J. R., Whitehouse, R. H., Edgson, A. C. (1959). The relationship of body build to the excretion of 17-ketosteroids and 17-ketogenic steroids in healty young men. J. Endocr., 19: 87–101.Google Scholar