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Human Placental Lactogen and dU-Estrogen Levels in Normal Twin Pregnancies

Published online by Cambridge University Press:  01 August 2014

B. Kappel ,
K. Hansen ,
J. Moller  and
J. Faaborg-Andersen
B. Kappel*
Affiliation:
Department of Obstetrics and Gynecology, Kommunehospital, Aarhus, Denmark
K. Hansen
Affiliation:
Department of Obstetrics and Gynecology, Kommunehospital, Aarhus, Denmark
J. Moller
Affiliation:
Department of Obstetrics and Gynecology, Kommunehospital, Aarhus, Denmark
J. Faaborg-Andersen
Affiliation:
Department of Obstetrics and Gynecology, Kommunehospital, Aarhus, Denmark
*
Cytogenetic Laboratory, Aarhus Psychiatric Hospital, DK-8240 Risskov, Denmark

Abstract

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Reference intervals for human placental lactogen (hPL) and dU-estrogens (dU-E) in uncomplicated twin pregnancies are found to be higher than singleton pregnancies and considerably wider. Significantly more monozygotic than dizygotic pregnancies, and significantly more monoplacental than diplacental pregnancies showed hPL values below the median on the normal range curve. The same was not found for dU-E. Significantly more growth-retarded fetuses were found in monoplacental than diplacental pregnancies. The benefit of measuring the two parameters in order to identify the intrauterine growth retarded fetuses were evaluated in terms of sensitivity and specificity. Both parameters were found less suitable for the purpose.

Keywords

Twin pregnancyHormone reference intervalsHuman placental lactogendU-estrogensIntrauterine growth retardation
Type
Review Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 34 , Issue 1-2 , April 1985 , pp. 59 - 65
Copyright
Copyright © The International Society for Twin Studies 1985

References

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