Hostname: page-component-848d4c4894-pftt2 Total loading time: 0 Render date: 2024-05-31T21:35:54.593Z Has data issue: false hasContentIssue false
  • English
  • Français

The Red Cell Acid Phosphatase Polymorphism in Greek b-Thalassemia Patients

Published online by Cambridge University Press:  01 August 2014

A. Kalos ,
K. Melissinos ,
A. Archimandritis ,
G. Kourounis  and
B. Angelopoulos
A. Kalos*
Affiliation:
Department of Pathologic Physiology, Medical School, State University of Athens, Greece
K. Melissinos
Affiliation:
Department of Pathologic Physiology, Medical School, State University of Athens, Greece
A. Archimandritis
Affiliation:
Department of Pathologic Physiology, Medical School, State University of Athens, Greece
G. Kourounis
Affiliation:
Department of Pathologic Physiology, Medical School, State University of Athens, Greece
B. Angelopoulos
Affiliation:
Department of Pathologic Physiology, Medical School, State University of Athens, Greece
*
11a Charitos St., Athens (139), Greece

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Red cell acid phosphatase polymorphism was studied by starch gel electrophoresis in 70 b-thalassemia patients and in 310 healthy Greeks. Our results gave the following gene frequencies: b-thalassemia patients: pa 0.321, pb 0.643, pc 0.036; healthy Greeks: pa 0.302, pb 0.653, pc 0.045. No statistically significant differences were found between the two groups.

Type
Short Notes
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 24 , Issue 3-4 , 07-10 1975 , pp. 337 - 338
Copyright
Copyright © The International Society for Twin Studies 1975

References

REFERENCES

Bailey, N. 1969. Statistical Methods in Biology. London: English Universities Press.Google Scholar
Conneally, P., Nevo, S., Cleguhorn, T., Harris, H., Hopkinson, D., Rolson, E., Spencer, N., Steinberg, A. 1965. Linkage studies with the human red blood cell acid phosphatase locus and blood groups, Hp, Gm and Inv loci. Am. J. Hum. Genet., 17: 109.Google ScholarPubMed
Giblett, E.R. 1969. Genetic Markers in Human Blood [pp. 424]. Oxford: Blackwell.Google Scholar
Hopkinson, D.A., Spencer, N., Harris, H. 1963. Red cell acid phosphatase variants: a new human polymorphism. Nature (Lond.), 199: 969.CrossRefGoogle ScholarPubMed
Hopkinson, D.A., Spencer, N., Harris, H. 1964. Genet-ical studies on human red cell acid phosphatase. Hum. Genet., 16: 141.Google ScholarPubMed
Hopkinson, D.A., Harris, H. 1968. In: Biochemical Methods in Red Cell Genetics. New York: Academic Press.Google Scholar
Kattamis, Ch., Chaidas, A., Kyriazakou, M., Luffman, J.E., Hopkinson, D.A. 1965. Electrophoretic types of red cell acid phosphatase in Greece, [in Greek]. Ped. Bull., Athens University, 12: 381.Google Scholar
Schlesinger, D., Sulich, J. 1970. Types of acid phosphatase of erythrocytes in the Polish population. Arch. Immunol. Ther. Exp. (Warsz.), 18: 54.Google ScholarPubMed
Stamatoyannopoulos, G., Thomakos, G., Giblett, E.R. 1975. Red cell enzyme polymorphisms in the Greek populations. Humangenetik, 27: 23.CrossRefGoogle ScholarPubMed