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Prostaglandins in the saliva of the cattle tick, Boophilus microplus (Canestrini) (Acarina, Ixodidae)

Published online by Cambridge University Press:  10 July 2009

G. A. Higgs
Affiliation:
Wellcome Research Laboratories, Langley Court, Beckenham, Kent, U.K.
J. R. Vane
Affiliation:
Wellcome Research Laboratories, Langley Court, Beckenham, Kent, U.K.
R. J. Hart
Affiliation:
Wellcome Research Laboratories, Berkhamsted Hill, Berkhamsted, Herts., U.K.
C. Potter
Affiliation:
Wellcome Research Laboratories, Berkhamsted Hill, Berkhamsted, Herts., U.K.
R. G. Wilson
Affiliation:
Wellcome Research Laboratories, Berkhamsted Hill, Berkhamsted, Herts., U.K.

Abstract

Saliva was obtained by applying capillary tubes to the mouthparts of the cattle tick, Boophilus microplus (Can.), after the subcuticular injection of pilocarpine hydrochloride. Acid-lipid extracts of this saliva showed prostaglandin (PG)-like activity on bioassay. Chromatographic studies confirmed this activity as being due to PGE2. Extracts from homogenates of B. microplus larvae and salivary gland tissue also showed prostaglandin-like activity. A role for PGs in B. microplus feeding mechanisms is discussed.

Type
Original Articles
Copyright
Copyright © Cambridge University Press 1976

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