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Hypothermic modulation of anoxic brain injury in adult survivors of cardiac arrest: a review of the literature and an algorithm for emergency physicians

Published online by Cambridge University Press:  21 May 2015

Robert S. Green  and
Daniel Howes
Robert S. Green*
Affiliation:
Departments of Emergency Medicine and Internal Medicine; Division of Critical Care Medicine, Dalhousie University, Halifax, NS
Daniel Howes
Affiliation:
Department of Emergency Medicine and Critical Care Medicine, Queen's University, Kingston, Ont.
*
Emergency Medicine and Critical Care Medicine, Dalhousie University, Rm. 355 Bethune Building, 1278 Tower Rd., Halifax NS B3H 2Y9; 902 473-79215; rgreen@hfx.eastlink.ca

Abstract

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Anoxic brain injury is a common outcome after cardiac arrest. Despite substantial research into the pathophysiology and management of this injury, a beneficial treatment modality has not been previously identified. Recent studies show that induced hypothermia reduces mortality and improves neurological outcomes in patients resuscitated from ventricular fibrillation. This article reviews the literature on induced hypothermia for anoxic brain injury and summarizes a treatment algorithm proposed by the Canadian Association of Emergency Physicians Critical Care Committee for hypothermia induction in cardiac arrest survivors.

Keywords

cardiac arresthypothermiainducedanoxic brain injuryhypothermia algorithminduced
Type
State of the Art • Selon les règles de l’art
Information
Canadian Journal of Emergency Medicine , Volume 7 , Issue 1 , January 2005 , pp. 42 - 47
Copyright
Copyright © Canadian Association of Emergency Physicians 2005

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