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Complete closure of the ductus arteriosus in the foetus with transposition of the great arteries

Published online by Cambridge University Press:  24 March 2020

Agnieszka Grzyb Open the ORCID record for Agnieszka Grzyb [Opens in a new window] ,
Adam Koleśnik ,
Dariusz Gruszfeld  and
Joanna Szymkiewicz-Dangel
Agnieszka Grzyb
Affiliation:
Department of Perinatal Cardiology and Congenital Anomalies, Centre of Postgraduate Medical Education, Warsaw, Poland Department of Cardiology, The Children’s Memorial Health Institute, Warsaw, Poland
Adam Koleśnik
Affiliation:
Department of Perinatal Cardiology and Congenital Anomalies, Centre of Postgraduate Medical Education, Warsaw, Poland Department of Cardiology, The Children’s Memorial Health Institute, Warsaw, Poland Cardiovascular Interventions Laboratory, The Children’s Memorial Health Institute, Warsaw, Poland
Dariusz Gruszfeld
Affiliation:
Department of Neonatology and Neonatal Intensive Care, The Children’s Memorial Health Institute, Warsaw, Poland
Joanna Szymkiewicz-Dangel*
Affiliation:
Department of Perinatal Cardiology and Congenital Anomalies, Centre of Postgraduate Medical Education, Warsaw, Poland
*
Author for correspondence: J. Szymkiewicz-Dangel, Department of Perinatal Cardiology and Congenital Anomalies, Centre of Postgraduate Medical Education, Agatowa 10, 03-680Warsaw, Poland. Tel: +48 22 510 26 08; Fax: +48 22 678 99 32. E-mail: jdangel@cmkp.edu.pl
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Abstract

Prenatal restriction of the ductus arteriosus can manifest as persistent pulmonary hypertension in the newborn, especially dangerous with the transposition of the great arteries. Its aetiology has long been related to maternal intake of non-steroidal anti-inflammatory drugs; however, some other substances, including polyphenols, may have similar properties. We describe a case of complete prenatal closure of the ductus arteriosus in the foetus with transposition of the great arteries. The newborn presented with pulmonary hypertension unresponsive to pharmacotherapy and died of multi-organ failure.

Keywords

Transposition of the great arteriesductus arteriosuspulmonary hypertensionfoetal medicineprenatal diagnosis
Type
Brief Report
Information
Cardiology in the Young , Volume 30 , Issue 4 , April 2020 , pp. 588 - 590
Copyright
© The Author(s), 2020. Published by Cambridge University Press

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References

Wernovsky, G.Transposition of the great arteries. In: Allen, HD, Driscoll, DJ, Shaddy, RE, Feltes, TF (ed.). Moss & Adams Heart Disease in Infants, Children, and Adolescents In cluding the Fetus and Young Adult, 8th edn. Lippincott Williams & Wilkins, Philadelphia, 2013: 1097–1146.Google Scholar
Karimi, M, Kirshbom, PM, Kopf, GS, Steele, MM, Sullivan, JM. Persistent pulmonary hypertension in a neonate with transposition of great arteries and intact ventricular septum: a case report and review of the literature. World J Pediatr Congenital Heart Surg 2015; 6: 462–465.CrossRefGoogle Scholar
Mathew, B, Lakshminrusimha, S. Persistent pulmonary hypertension in the newborn. Children 2017; 4: 63.CrossRefGoogle ScholarPubMed
Roofthooft, MT, Bergman, KA, Waterbolk, TW, Ebels, T, Bartelds, B, Berger, RM. Persistent pulmonary hypertension of the newborn with transposition of the great arteries. Ann Thorac Surg 2007; 83: 1446–1450.CrossRefGoogle ScholarPubMed
Sallaam, S, Natarajan, G, Aggarwal, S. Persistent pulmonary hypertension of the newborn with D-transposition of the great arteries: management and prognosis. Congenital Heart Dis 2015; 11: 239–244.10.1111/chd.12304CrossRefGoogle ScholarPubMed
Maeno, YV, Kamenir, SA, Sinclair, B, van der Velde, ME, Smallhorn, JF, Hornberger, LK. Prenatal features of ductus arteriosus constriction and restrictive foramen ovale in d-transposition of the great arteries. Circulation 1999; 99: 1209–1214.CrossRefGoogle ScholarPubMed
Kumar, A, Taylor, GP, Sandor, GG, Patterson, MW. Pulmonary vascular disease in neonates with transposition of the great arteries and intact ventricular septum. Br Heart J 1993; 69: 442–445.CrossRefGoogle ScholarPubMed
Zielinsky, P, Busato, S. Prenatal effects of maternal consumption of polyphenol-rich foods in late pregnancy upon fetal ductus arteriosus. Birth Defects Res Part C Embryo Today Rev 2013; 99: 256–274.CrossRefGoogle ScholarPubMed
Ema.europa.eu. European Medicines Agency - Find medicine – Tractocile, 2019. Retrieved November 10, 2017, from http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/000253/human_med_001101.jsp&mid=WC0b01ac058001d124.Google Scholar
Donofrio, MT. Images in cardiovascular medicine. Premature closure of the foramen ovale and ductus arteriosus in a fetus with transposition of the great arteries. Circulation 2002; 105: e65–e66.CrossRefGoogle Scholar

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