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The effect of atrial septostomy on the concentration of brain-type natriuretic peptide in patients with idiopathic pulmonary arterial hypertension

Published online by Cambridge University Press:  01 October 2007

Michael L O’Byrne ,
Erika S Berman Rosenzweig  and
Robyn J Barst
Michael L O’Byrne
Affiliation:
Columbia University College of Physicians and Surgeons New York, New York, USA
Erika S Berman Rosenzweig
Affiliation:
Columbia University College of Physicians and Surgeons New York, New York, USA
Robyn J Barst*
Affiliation:
Columbia University College of Physicians and Surgeons New York, New York, USA
*
Correspondence to: Robyn J Barst, MD, New York Presbyterian Pulmonary Hypertension Center, Morgan Stanley Children’s Hospital of New York, 3959 Broadway BHN 2-262, New York, NY 10032, USA. Tel: (212) 305-4436; Fax: (212) 342-1443; E-mail: rjb3@columbia.edu
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Abstract

Atrial septostomy has improved haemodynamics and clinical symptoms in selected patients with idiopathic pulmonary arterial hypertension. We found that, in 5 patients with idiopathic pulmonary arterial hypertension, septostomy resulted in decreased levels of brain-type natriuretic peptide, and improvement in symptoms of cardiac failure, suggesting that serial measurements of the peptide may have clinical utility.

Keywords

Heart failurecardiac catheterizationatrial natriuretic peptide
Type
Brief Report
Information
Cardiology in the Young , Volume 17 , Issue 5 , October 2007 , pp. 557 - 559
Copyright
Copyright © Cambridge University Press 2007

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