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Myocarditis in drug rash with eosinophilia and systemic symptoms

Published online by Cambridge University Press:  19 September 2014

Cynthia H. Ho  and
Merujan Y. Uzunyan
Cynthia H. Ho*
Affiliation:
Department of Pediatrics, Keck School of Medicine, Los Angeles County + University of Southern California Medical Center, Los Angeles, California, United States of America Department of Internal Medicine, Keck School of Medicine, Los Angeles County + University of Southern California Medical Center, Los Angeles, California, United States of America
Merujan Y. Uzunyan
Affiliation:
Department of Pediatrics, Keck School of Medicine, Los Angeles County + University of Southern California Medical Center, Los Angeles, California, United States of America Division of Cardiology, Keck School of Medicine, Los Angeles County + University of Southern California Medical Center, Los Angeles, California, United States of America
*
Correspondence to: C. H. Ho, MD, Keck School of Medicine, Los Angeles County+University of Southern California Medical Center, 2020 Zonal Avenue, IRD Room 109, Los Angeles, CA 90033, United States of America. Tel: +323 226 3691; Fax: +323 226 5692; E-mail: cynho@usc.edu
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Abstract

Drug rash with eosinophilia and systemic symptoms is a drug hypersensitivity reaction. Hepatitis and nephritis are the most common visceral manifestations. Myocarditis is important to recognise, given the high mortality rate. We describe a child with drug rash with eosinophilia and systemic symptoms and discuss the role of N-terminal pro-hormone of basic natriuretic peptide in early recognition of associated myocarditis.

Keywords

Drug-induced hypersensitivity syndromeeosinophilic myocarditisN-terminal pro-hormone of basic natriuretic peptidedrug rash with eosinophilia and systemic symptomsdrug-induced hypersensitivity syndrome
Type
Brief Reports
Information
Cardiology in the Young , Volume 25 , Issue 6 , August 2015 , pp. 1210 - 1213
Copyright
© Cambridge University Press 2014 

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