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Nit-Occlud atrial septal defect occluder device: Histological characterisation of the healing process

Published online by Cambridge University Press:  24 March 2021

Elodie Perdreau*
Affiliation:
IHU Liryc, Electrophysiology and Heart Modeling Institute, Fondation Bordeaux Université, F-33600 Pessac-Bordeaux, France Université de Bordeaux, Centre de recherche Cardio-Thoracique de Bordeaux, U1045, F-33000, Bordeaux, France INSERM, Centre de recherche Cardio-Thoracique de Bordeaux, U1045, F-33000 Bordeaux, France
Zakaria Jalal
Affiliation:
IHU Liryc, Electrophysiology and Heart Modeling Institute, Fondation Bordeaux Université, F-33600 Pessac-Bordeaux, France Université de Bordeaux, Centre de recherche Cardio-Thoracique de Bordeaux, U1045, F-33000, Bordeaux, France INSERM, Centre de recherche Cardio-Thoracique de Bordeaux, U1045, F-33000 Bordeaux, France Bordeaux University Hospital (CHU), Congenital and Pediatric Cardiology Unit, F-33600 Pessac, France
Matthias Sigler
Affiliation:
Georg-August University, Pediatric Cardiology and Intensive Care Medicine, Göttingen, Germany
*
Author for correspondence: Dr Elodie Perdreau, IHU Liryc, Electrophysiology and Heart Modeling Institute, Fondation Bordeaux Université, F-33600 Pessac-Bordeaux, France. Tel: +33 (0)5 35 38 19 99. E-mail: elop85@yahoo.fr

Abstract

We describe the healing process following transcatheter implantation of the Nit-Occlud ASD-R occluder (PFM medical, Cologne, Germany) for atrial septal defect closure in a sheep model with histological confirmation of neotissue formation covering the device.

Type
Images in Congenital Cardiac Disease
Copyright
© The Author(s), 2021. Published by Cambridge University Press

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References

Foth, R, Quentin, T, Michel-Behnke, I et al. Immunohistochemical characterization of neotissues and tissue reactions to septal defect–occlusion devices. Circ Cardiovasc Interv 2009; 2: 9096.CrossRefGoogle ScholarPubMed