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The re-occurrence of dilated cardiomyopathy in propionic acidemia after liver transplantation requiring heart transplant, first case from Middle East

Part of: Metabolic

Published online by Cambridge University Press:  16 February 2022

Yahia Hejazi ,
Ziyad M. Hijazi ,
Hesham Al-saloos  and
Tawfeg Ben Omran
Yahia Hejazi*
Affiliation:
Division of Cardiology, Department of Pediatrics, Sidra Medicine, Doha, Qatar
Ziyad M. Hijazi
Affiliation:
Division of Cardiology, Department of Pediatrics, Sidra Medicine, Doha, Qatar
Hesham Al-saloos
Affiliation:
Division of Cardiology, Department of Pediatrics, Sidra Medicine, Doha, Qatar
Tawfeg Ben Omran
Affiliation:
Division of Clinical and Metabolic Genetics, Department of Pediatrics, Sidra Medicine, Doha, Qatar
*
Author for correspondence: Y. Hejazi, Pediatric Cardiology Fellow, Division of Cardiology, Department of Pediatrics, Sidra Medicine, Qatar Foundation, Al Luqta Street, Education City North Campus, PO Box 26999, Doha, Qatar. Tel +97450244353. Email: Yahia.hejazi@gmail.com
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Abstract

Propionic acidemia is a rare autosomal recessive inborn error of metabolism. It is relatively common in Middle East. Dilated cardiomyopathy is one of the leading causes of morbidity and mortality for patients with propionic acidemia. Liver transplantation has been used for patient with frequent metabolic decompensations and was shown to be beneficial in propionic acidemia-related dilated cardiomyopathy. Up to our knowledge, there has been one reported case of recurrent dilated cardiomyopathy 3 years after liver transplantation. We report the first case, from Middle East, of recurrent dilated cardiomyopathy, 6 years after liver transplantation.

Keywords

Propionic acidemiadilated cardiomyopathyliver transplantationinborn error of metabolism
Type
Original Article
Information
Cardiology in the Young , Volume 33 , Issue 1 , January 2023 , pp. 86 - 89
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Copyright
© The Author(s), 2022. Published by Cambridge University Press

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