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Cerebral Mechanisms in Obsessive-Compulsive Disorder

Published online by Cambridge University Press:  07 November 2014

Juan Carlos Goldar ,
Dario Rojas  and
Mariano Outes
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Abstract

Brain lesions cause different level change in cerebral function. They may conflict with the existing antagonistic mechanisms between the dorsal and ventral brain. At a clinical level, a dorsal brain lesion may constitute praxis disorders, while a ventral lesion may represent preventive inhibition. Further instinctive symptoms originate in the cingulate gyrus and its connections with the thalamic peduncle. This area may be an importan obsessive-compulsive disorder (OCD) pathway, that is utilized therapeutically during neurosurgical interventions in OCD.

Type
Feature Articles
Information
CNS Spectrums , Volume 3 , Issue 7: Novel Neuropsychiatric Conceptualizations , August 1998 , pp. 44 - 46
Copyright
Copyright © Cambridge University Press 1998

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References

REFRENCES

1.Broca, P. Anatomie comparée des circonvolutions cérébrales: le grand lobe limbique et la soissure limbique dans la série des mammiferes. Rev Anthropol. (Paris). 1878;1:385–498.Google Scholar
2.Spatz, H. Über die Bedeutung der basale Rinde. Z Neurol. 1937;158:208–224.Google Scholar
3.Goldar, JC. Corteza cerebral y psiquiatría. Acta Psiquiatr Psicol Am Lot. 1991;37:8.Google Scholar
4.Goldar, JC, Hojas, D, Outes, M. Un modelo neurobiológico de la mente. Acta Psiquiatr Psicol Am Lat. 1993;39:33–44.Google Scholar
5.Starkstein, S, Robinson, R. Mechanism of disinhibition after brain lesions. J Nerv Mental Dis. 1997;185:108–114.Google Scholar
6.Broca, P. Remarques sur le siege de la faculté du language articulé, suivier d'une observation d'aphemie (perte de la parole). Bulletin Societe Anatomie. (Paris) 1861;6:330–336.Google Scholar
7.Wernicke, C. Der aphasische Symptomcomplex. Eine psychologische Studie auf anatomischer Basis. Breslau: Cohn and Weigert; 1874.Google Scholar
8.Dejerine, J. Sur un cas de cecite verbale avec agraphie suive d'autopsie. Mémoires Societe Biologie. 1891;3:197–201.Google Scholar
9.Liepmann, H. Das Krankheitsbild der Apraxia (motorische Asymbolic) auf Grund eines Falles von eiseitiger Apraxie. Monatssch Psich Neurol. 1900;15–44, 102–132, 182–197.Google Scholar
10.Stamm, J. The function of the median cerebral cortex in maternal behavior of rats. J Comp Physiol Psychol. 1955;48:347–356.CrossRefGoogle ScholarPubMed
11.Spencer, S, Spencer, D, Williamson, P, Mattsom, R. Sexual automations in complex partial seizures. Neurology. 1983;33:537–533.Google Scholar
12.Hirose, S. Clinical pictures and courses of four cases with limbic epilepsy: a special reference to their relationship to EEg pattern. In: Doane, BK, Livingstone, KE, eds. The Limbic System: Functional Organization and Clinical Disorders. New York, NY: Raven Press; 1986.Google Scholar
13.Baleydier, C, Maugiera, F. The duality of the cingulate gyrus in monkey. Neuroanatomical study and functional hypothesis. Brain. 1980;103:525–554.Google Scholar
14.Economic, C. Von Zellaubau der Grosshirnrinde des Menschen. Berlin, Germany: Springer; 1927.Google Scholar
15.Pandya, D, Kuypers, H. Cortico-cortical connections in the rhesus monkey. Brain Res. 1969;13:13–36.Google Scholar
16.Morecraft, R, Van Hoesen, G. Cingulate input to the primary and supplementary motor cortices in the rhesus monkey: evidence for somatotopy in areas 24c and 23c. J Comp Neurol. 1992;322:471–489.Google Scholar
17.Morecraft, R, Van Hoesen, G. Frontal granular cortex input to the cingulate (M3), supplementary (M2), and primary (Ml) motor cortices in the rhesue monkey. J Comp Neurol. 1993;337:669–688.Google Scholar
18.Ray, J, Price, J. The organization of projections from the mediodorsal nucleus of the thalamus to orbital and medial prefrontal cortex in kacaque monkeys. J Comp Neurol. 1993;337:1–31.Google Scholar
19.Flechsig, P. Anatomie des Menschlichen: Gehirns und Rückenmarks. Leipzig, Germany: Thieme; 1920.Google Scholar
20.Welt, L. Über Charakterveränderungen des menschen infolge von läsionen des stirnhirns. Deutches Archiv klin Med. 1888;42:339–390.Google Scholar
21.Kleist, K. Bericht über die gehirnpathologie in ihrer bedeutung für neurologie und psychiatrie. Zeitsch ges Neurol Psychiat. 1937;158:159–193.Google Scholar
22.Goldar, JC, Outes, D. FisiopatologÍa de la desinhibición instintiva. Acta Psiquiatr Psicol Am Lat. 1972;18:177–185.Google Scholar
23.Goldar, JC. Cerebro Límbico y Psiquiatría. Buenos Aires, Argentina: Salerno; 1975.Google Scholar
24.Klüver, H, Buccy, P. Preliminary analysis of functions of the temporal lobes in monkeys. Arch Neurol Psychist. 1939;42:979–1000.Google Scholar
25.Insel, T. Toward a neuroanatomy of obsessive-compulsive disorder. Arch Gen Psychiatry. 1992;49:739–744.Google Scholar
26.Dart, R. The dual structure of the neopallium: its history and significance. J Anat. 1934;69:3–19.Google Scholar
27.Barbas, N, Pandya, D. Architecture and intrinsic connections of the prefrontal cortex in the rhesus monkey. J Comp Neurol. 1989;286:353–375.Google Scholar