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Further evaluation of one-point microcapsule agglutination test for diagnosis of leptospirosis

Published online by Cambridge University Press:  19 October 2009

J. J. Cui
Affiliation:
Chengdou Institute of Biological Products, Chengdou, China
G. X. Xiao
Affiliation:
Chengdou Institute of Biological Products, Chengdou, China
T. Z. Chen
Affiliation:
Chengdou Institute of Biological Products, Chengdou, China
G. F. Zhu
Affiliation:
Institute of Epidemiology and Microbiology China National Center for Prevention Medicine, Beijing, China
T. Sato
Affiliation:
Japan Lyophilization Laboratories, Tokyo, Japan
M. Seki
Affiliation:
Japan Lyophilization Laboratories, Tokyo, Japan
S. Kobayashi
Affiliation:
The TAMA Research Institute, Tokyo, Japan
Y. Arimitsu*
Affiliation:
Department of Applied Immunology, National Institute of Health, Tokyo, Japan
*
Correspondence should be addressed to: Dr. Y. Arimitsu, Department of Applied Immunology, National Institute of Health, 2-10 Kamiosaki 2-chome, Shinagawaku, Tokyo 141, Japan.
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Summary

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A total of 100 serum samples including 22 acute phase sera and 39 paired sera collected from clinically diagnosed cases of leptospirosis in Ming-shan County, Sichuan Province, China were examined by the one-point microcapsule agglutination test (MCAT), which was developed in Japan, and by conventional microscopic agglutination tests (MAT). The one-point MCAT is more reactive to IgM antibody than MAT and is superior in detecting antibodies in the early stages of the disease.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1991

References

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