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The lysis of Bacterium coli by amino-acids

Published online by Cambridge University Press:  15 May 2009

J. Gordon ,
R. A. Hall  and
L. H. Stickland
J. Gordon
Affiliation:
The School of Medicine, Leeds
R. A. Hall
Affiliation:
The School of Medicine, Leeds
L. H. Stickland
Affiliation:
The School of Medicine, Leeds
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1. Straight-chain α-amino-acids are all equally effective in causing the lysis of Bact. coli.

2. Various modifications of this structure always result in a decrease of this lytic activity.

3. The optical isomers of α-amino-acids are equally effective in causing lysis.

4. There is a correlation between the lytic and the bactericidal powers of the amino-acids and their derivatives.

Type
Research Article
Information
Journal of Hygiene , Volume 52 , Issue 4 , December 1954 , pp. 510 - 515
Copyright
Copyright © Cambridge University Press 1954

References

Adamson, D. W. (1939). A new synthesis of basic amino-acids and glycine. J. chem. Soc. p. 1564.CrossRefGoogle Scholar
Bergmann, M. & Grafe, K. (1930). Synthese eines Peptids und anderer Abkömmlinge der α-aminoacrylsäure (Dehydroalanin) aus Brenztraubensäure. Z. physiol. Chem. 187, 187.CrossRefGoogle Scholar
De Witt, C. C. (1943). γ-amino-butyric acid. Organ. Synth. (New York), 2, 25.Google Scholar
Gordon, J., Hall, R. A. & Stickland, L. H. (1951). The kinetics of the lysis of Bacterium coli by glycine. J. Hyg., Camb., 49, 169.Google ScholarPubMed
Gordon, J., Hall, R. A. & Stickland, L. H. (1952). The reciprocal resistance to various amino-acids of strains of Bact. coli made resistant to one of them. J. Path. Bact. 64, 299.CrossRefGoogle ScholarPubMed
Gordon, J., Hall, R. A. & Stickland, L. H. (1953). The inhibition by various agents of the lysis of Bacterium coli by glycine. J. Hyg., Camb., 51, 215.CrossRefGoogle ScholarPubMed
Neuberg, C. (1906). Synthese von Oxy- und Diaminosäuren. III. Mitteilung. Über α-α-Diaminoazelainsäure, αβ-Diaminobuttersäure und α-Oxy-β-aminobuttersäure. Chem. Zbl. 2, 765.Google Scholar
Pacsu, E. & Mullen, J. W. (1940). An improved method for the resolution of synthetic alanine. J. biol. Chem. 136, 365.CrossRefGoogle Scholar
Robinson, H. W. & Hogden, C. G. (1940). The biuret reaction in the determination of serum proteins. J. biol. Chem. 135, 727.CrossRefGoogle Scholar
Stickland, L. H. (1951). The determination of small quantities of bacteria by means of the biuret reaction. J. gen. Microbiol. 5, 698.CrossRefGoogle ScholarPubMed