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A new antigenic relationship among faecal bacilli due to a common β antigen

Published online by Cambridge University Press:  15 May 2009

Rose Mushin
Affiliation:
From the School of Bacteriology, University of Melbourne
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1. The presence of a new thermolabile an named β antigen has been demonstrated in motile and non-motile coliform, paracolon and Proteus strains, and in Shigella bacilli (Sh. flexneri Sh. flexneri V1 and D19). This antigen can be frequently found in the above types.

2. The characteristics of the β antigen have been described, and its dissimilarity to H, O, Vi, 2, A, B and α antigens has been established.

3. A high incidence of β antibodies was demonstrated in normal human and rabbit sera.

4. β strains of paracolon and coliform b injected intraperitoneally into mice were shown to be more virulent to mice than β minus forms of the same strains.

5. It is suggested that unrecognized presence of β antigen in cultures and β antibody in human and rabbit sera may cause errors in bacteriological and serological diagnoses of enteric infections.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1949

References

REFERENCES

Berger, F. M. (1945). A new non-mannite fermenting dysentery organism of the Flexner group. J. Hyg., Camb., 44, 116.CrossRefGoogle ScholarPubMed
Bridges, R. F. & Taylor, J. (1946). A critical examination of the organism described as Bacillus wakefield. J. Hyg., Camb., 44, 346.Google ScholarPubMed
Crossley, V. M., Ferguson, M. & Brydson, L. (1946). The use of soluble starch medium in the preparation of smooth ‘O’ Salmonella antigens. J. Bact. 52, 367.CrossRefGoogle ScholarPubMed
Cruickshank, J. C. (1939). Somatic and X agglutinins to the Salmonella group. J. Hyg., Camb., 39, 224.CrossRefGoogle Scholar
Felix, A. & Pitt, R. M. (1934 a). Virulence to B. typhosus and resistance of O antibody. J. Path. Bact. 38, 409.CrossRefGoogle Scholar
Felix, A. & Pitt, R. M. (1934 b). A new antigen of B. typhosus. Lancet, 2, 186.CrossRefGoogle Scholar
Julianelle, L. A. (1937). Immunological specificity of Bacterium aerogenes and its antigenic relation to Pneumococcus type II, and Friedländer's Bacillus, type B. J. Immunol. 32, 21.CrossRefGoogle Scholar
Kauffmann, F. (1943). Über neue thermolabile Körper-antigene der Coli-Bakterien. Acta path, microbiol. scand. 20, 21.Google Scholar
Kauffmann, F. (1944). Zur Serologie der Coli-gruppe. Acta path, microbiol. scand. 21, 20.CrossRefGoogle Scholar
Kauffmann, F. (1947). The serology of the Coli group. J. Immunol. 57, 71.CrossRefGoogle ScholarPubMed
Knipschildt, H. E. (1945). Demonstration of capsular antigens. Acta path, microbiol. scand. 22, 44.CrossRefGoogle Scholar
Knipschildt, H. E. (1946). Demonstration of a new thermolabile antigen in the colon group. Acta path. microbiol. scand. 23, 179.CrossRefGoogle Scholar
Smith, T. (1928). The relation of the capsular substance of B. coli to antibody production. J. Exp. Med. 48, 351.CrossRefGoogle ScholarPubMed
Smith, T. & Bryant, G. (1927). Studies on pathogenic B. coli from bovine sources. J. Exp. Med. 46, 133.CrossRefGoogle ScholarPubMed
Stamp, Lord, & Stone, D. M. (1944). An agglutinogen common to certain strains of lactose and non-lactose-fermenting coliform bacilli. J. Hyg., Camb., 43, 266.Google ScholarPubMed
Topley, W. W. C. & Ayrton, J. (1924). Further investigations into the biological characteristics of B. enteritidis (Aertrycke). J. Hyg., Camb., 23, 198.CrossRefGoogle ScholarPubMed