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Studies in bacterial Variability. The Experimental Production of a Mucoid form of B. paratyphosus B

Published online by Cambridge University Press:  15 May 2009

E. W. Ainley Walke
E. W. Ainley Walke
Affiliation:
From the Department of Pathology, University of Oxford, A Report to the Medical Research Council.
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1. The experimental derivation of a mucoid form of B. paratyphosus B is described.

2. This form, though at one stage non-motile, agreed closely with the “capsulated mucoid forms” of paratyphoid B, isolated by W. Fletcher from two chronic “carrier” cases.

3. The mucoid paratyphoid B was highly dys-agglutinable, and it would not on serological examination be identified as a paratyphoid B.

4. Its colonies were also entirely unlike colonies of paratyphoid B, being large, slimy, and usually dome-shaped, though at other stages of their metamorphosis they presented either an umbilication, or a nipple-like elevation in the centre.

5. The mucoid bacillus possessed the distinctive sugar reactions of paratyphoid B.

6. On suitable manipulation it reverted to the ordinary form.

Type
Research Article
Information
Journal of Hygiene , Volume 21 , Issue 1 , June 1922 , pp. 87 - 92
Copyright
Copyright © Cambridge University Press 1922

References

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