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Activation of human leukocytes by acute hypoxia

Published online by Cambridge University Press:  25 January 2001

Dimitris Sanidas ,
Andrew Garnham  and
Rubina Mian
Dimitris Sanidas
Affiliation:
Department of Biomedical Sciences, School of Natural & Environmental Sciences, Coventry University, Cox Street Coventry, CV1 5FB and Department of Surgery QE Hospital Edgbaston, Birmingham, UK
Andrew Garnham
Affiliation:
Department of Biomedical Sciences, School of Natural & Environmental Sciences, Coventry University, Cox Street Coventry, CV1 5FB and Department of Surgery QE Hospital Edgbaston, Birmingham, UK
Rubina Mian
Affiliation:
Department of Biomedical Sciences, School of Natural & Environmental Sciences, Coventry University, Cox Street Coventry, CV1 5FB and Department of Surgery QE Hospital Edgbaston, Birmingham, UK
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Abstract

Exposure of human leukocytes to 12 % and 6 % O2in vitro resulted in striking ultrastructural and morphological changes. These changes included the appearance of crater-like holes, a reduction in granular size and disruption of the cellular membrane. The implications of these findings is discussed. Experimental Physiology (2000) 85.3, 263-266.

Type
Research Article
Information
Experimental Physiology , Volume 85 , Issue 3 , May 2000 , pp. 263 - 266
Copyright
© The Physiological Society 2000

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