Skip to main content
×
Home
    • Aa
    • Aa

Directional selection and the evolution of sex and recombination

  • Brian Charlesworth (a1)
Abstract
Summary

Models of the evolutionary advantages of sex and genetic recombination due to directional selection on a quantitative trait are analysed. The models assume that the trait is controlled by many additive genes. A nor-optimal selection function is used, in which the optimum either moves steadily in one direction, follows an autocorrelated linear Markov process or a random walk, or varies cyclically. The consequences for population mean fitness of a reduction in genetic variance, due to a shift from sexual to asexual reproduction are examined. It is shown that a large reduction in mean fitness can result from such a shift in the case of a steadily moving optimum, under light conditions. The conditions are much more stringent with a cyclical or randomly varying environment, especially if the autocorrelation for a random environment is small. The conditions for spread of a rare modifier affecting the rate of genetic recombination are also examined, and the strength of selection on such a modifier determined. Again, the case of a steadily moving optimum is most favourable for the evolution of increased recombination. The selection pressure on a recombination modifier when a trait is subject to strong truncation selection is calculated, and shown to be large enough to account for observed increases in recombination associated with artificial selection. Theoretical and empirical evidence relevant to evaluating the importance of this model for the evolution of sex and recombination is discussed.

Copyright
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

A. Bergman & M. W. Feldman (1990). More on selection for and against recombination. Theoretical Population Biology 38, 6892.

B. Charlesworth (1989). The evolution of sex and recombination. Trends in Ecology and Evolution 4, 264267.

J. F. Crow (1970). Genetic loads and the cost of natural selection. In Mathematical Topics in Population Genetics (ed. K. Kojima ), pp. 128177. Berlin: Springer-Verlag.

M. W. Feldman & U. Liberman (1986). An evolutionary reduction principle for genetic modifiers. Proceedings of the National Academy of Sciences USA83, 48244827.

M. W. Feldman , F. B. Christiansen & L. D. Brooks (1980). Evolution of recombination in a constant environment. Proceedings of the National Academy of Sciences USA77, 48244827.

P. B. Flexon & C. F. Rodell (1982). Genetic recombination and directional selection for DDT resistance in Drosophila melanogaster. Nature 298, 672674.

J. H. Gillespie (1973). Polymorphism in random environments. Theoretical Population Biology 4, 193195.

J. B. S. Haldane & S. D. Jayakar (1963). Polymorphism due to selection of varying direction. Journal of Genetics 58, 237242.

S. Karlin & U. Liberman (1974). Random temporal variation in selection intensities: case of large population size. Theoretical Population Biology 5, 59103.

M. Kimura (1965). A stochastic model concerning the maintenance of genetic variability in quantitative characters. Proceedings of the National Academy of Sciences USA54, 731736.

A. S. Kondrashov (1988). Deleterious mutations and the evolution of sexual reproduction. Nature 336, 435440.

M. Lynch & W. Gabriel (1983). Phenotypic evolution and parthenogenesis. American Naturalist 122, 745764.

M. Lynch , W. Gabriel & A. M. Wood (1991). Adaptive and demographic responses of plankton populations to environmental change. Limnology and Oceanography 36, 13011312.

K. Mather (1943). Polygenic inheritance and natural selection. Biological Reviews 18, 3264.

M. Turelli (1984). Heritable variation via mutationselection balance: Lerch's zeta meets the abdominal bristle. Theoretical Population Biology 25, 138193.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Genetics Research
  • ISSN: 0016-6723
  • EISSN: 1469-5073
  • URL: /core/journals/genetics-research
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×