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The genetics of tasting in mice: VI. Saccharin, acesulfame, dulcin and sucrose

  • Ian E. Lush (a1)

Summary

Twenty-six strains of mice were tested for their reaction to four different sweet substances; saccharin, acesulfame, dulcin and sucrose. There was considerable strain variation in the degree to which they found the sweet substances preferable to water. The variation in preference for any one sweet substance is very highly correlated with the variation in preference for the other sweet substances. This is interpreted to mean that there is only one sweetness receptor, although an alternative explanation in terms of variation in psychological motivation is not discounted. The difference between C57BL/6Ty and DBA/2Ty is largely due to a single gene, Sac.

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References

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Arora, K., Rodrigues, V., Joshi, S., Shanbhag, S. & Siddiqi, O. (1987). A gene affecting the specificity of the chemosensory neurons of Drosophila. Nature (London) 330, 6263.
Berry, R. J., Jakobson, M. E. & Triggs, G. S. (1973). Survival in wild-living mice. Mammal Reviews 3, 4657.
Capretta, P. J. (1970). Saccharin and saccharin-glucose ingestion in two inbred strains of Mus musculus. Psychonomic Science 21, 133135.
Faurion, A. (1987). Physiology of the sweet taste. Progress in Sensory Physiology 8, 130201.
Fuller, J. M. (1974). Single locus control of saccharin preference in mice. Journal of Heredity 65, 3336.
Lush, I. E. (1981). The genetics of tasting in mice I. Sucrose octaacetate. Genetical Research 38, 9395.
Lush, I. E. (1984). The genetics of tasting in mice IV. Quinine. Genetical Research 4, 151160.
Lush, I. E. & Holland, G. (1988). The genetics of tasting in mice V. Glycine and cycloheximide. Genetical Research 52, 207212.
Pelz, W., Whitney, G. & Smith, J. C. (1973). Genetic influences on saccharin preference in mice. Physiology and Behaviour 10, 263265.
Shingai, T. & Beidler, L. M. (1985). Interstrain differences in bitter taste responses in mice. Chemical Senses 10, 5156.
Tanimura, T., Isono, K. & Yamamoto, M. T. (1988). Taste sensitivity to trehalose and its alteration by gene dosage in Drosophila melanogaster. Genetics 119, 399406.

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