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The transmission ratio distortion of the th2-haplotype in vivo and in vitro

Published online by Cambridge University Press:  14 April 2009

William Garside  and
Nina Hillman
William Garside
Affiliation:
Department of Biology, Temple University, Philadelphia, PA 19122
Nina Hillman
Affiliation:
Department of Biology, Temple University, Philadelphia, PA 19122
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Summary

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The th2-haplotype is transmitted at low frequencies (< 0·30) by + / th2 males in normal matings. In the studies described here, the transmission frequency of the th2-haplotype from Rb7 / th2 males was determined for normal and delayed matings and in vitro inseminations. The data show the transmission frequency from the two in vivo inseminations to be less than 0·30 and to be statistically equivalent. However, the in vitro transmission frequency (0·80) is significantly greater than either of the in vivo frequencies. The results show that the environment in which fertilization occurs affects the transmission frequency of this specific t-haplotype significantly.

Type
Research Article
Information
Genetics Research , Volume 53 , Issue 1 , February 1989 , pp. 25 - 28
Copyright
Copyright © Cambridge University Press 1989

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