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Additive Effect of Enterococcus faecium on Enterococcal Bloodstream Infections: A 14-Year Study in a Swiss Tertiary Hospital

Published online by Cambridge University Press:  02 January 2015

Maja Weisser ,
Selja Capaul ,
Marc Dangel ,
Luigia Elzi ,
Esther Kuenzli ,
Reno Frei  and
Andreas Widmer
Maja Weisser*
Affiliation:
Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland
Selja Capaul
Affiliation:
Division of Clinical Microbiology, Department of Laboratory Medicine, University Hospital Basel, Basel, Switzerland
Marc Dangel
Affiliation:
Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland
Luigia Elzi
Affiliation:
Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland
Esther Kuenzli
Affiliation:
Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland
Reno Frei
Affiliation:
Division of Clinical Microbiology, Department of Laboratory Medicine, University Hospital Basel, Basel, Switzerland
Andreas Widmer
Affiliation:
Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland
*
Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland (weisserm@uhbs.ch)
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Abstract

We investigated whether an increase in enterococcal bloodstream infections (BSIs) depends on the emergence of Enterococcus faecium in an area with low vancomycin-resistant enterococci prevalence. From 1999 to 2012, a linear increase in E. faecium BSI rates (0.009 per 1,000 patient-days per year; P<.001) was noted. Enterococcus faecalis BSI rates remained stable.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 34 , Issue 10 , October 2013 , pp. 1109 - 1112
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2013

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References

1.Moellering, RC JrEmergence of Enterococcus as a significant pathogen. Clin Infect Dis 1992;14(6):1173–1176.Google Scholar
2.Murdoch, DR, Mirrett, S, Harrell, LJ, Monahan, JS, Reller, LB. Sequential emergence of antibiotic resistance in enterococcal bloodstream isolates over 25 years. Antimicrob Agents Chemother 2002;46(11):3676–3678.Google Scholar
3.de Regt, MJ, van der Wagen, LE, Top, J, et al.High acquisition and environmental contamination rates of CC17 ampicillin-resistant Enterococcus faecium in a Dutch hospital. J Antimicrob Chemother 2008;62(6):1401–1406.CrossRefGoogle Scholar
4. Swiss Center for Antibiotic Resistance (anresis). anresis annual report 2013. Bern: anresis, 2013.Google Scholar
5.Homan, WL, Tribe, D, Poznanski, S, et al.Multilocus sequence typing scheme for Enterococcus faecium. J Clin Microbiol 2002;40(6):1963–1971.Google Scholar
6.Top, J, Schouls, LM, Bonten, MJ, Willems, RJ. Multiple-locus variable-number tandem repeat analysis: a novel typing scheme to study the genetic relatedness and epidemiology of Enterococcus faecium isolates. J Clin Microbiol 2004;42(10):4503–4511.Google Scholar
7.Boyce, JM, White, RL, Spruill, EY. Impact of methicillin-resistant Staphylococcus aureus on the incidence of nosocomial staphylococcal infections. J Infect Dis 1983;148(4):763.Google Scholar
8.Ammerlaan, HS, Harbarth, S, Buiting, AG, et al.Secular trends in nosocomial bloodstream infections: antibiotic-resistant bacteria increase the total burden of infection. Clin Infect Dis 2013;56(6):798–805.Google Scholar
9.Willems, RJ, Top, J, van Santen, M, et al.Global spread of vancomycin-resistant Enterococcus faecium from distinct nosocomial genetic complex. Emerg Infect Dis 2005;11(6):821–828.Google Scholar
10.Senn, L. Unprecedented nosocoimal spread of vancomycin-resistant Enterococcus faecium in a tertiary-care hospital in Switzerland. Paper presented at: BMC Proceedings, 2011, Geneva.Google Scholar