Hostname: page-component-8448b6f56d-sxzjt Total loading time: 0 Render date: 2024-04-25T01:26:06.548Z Has data issue: false hasContentIssue false
  • English
  • Français

Risk Factors for Development of Intestinal Colonization with Imipenem-Resistant Pseudomonas aeruginosa in the Intensive Care Unit Setting

Published online by Cambridge University Press:  02 January 2015

Anthony D. Harris ,
J. Kristie Johnson ,
Kerri A. Thom ,
Daniel J. Morgan ,
Jessina C. McGregor ,
Adebola O. Ajao ,
Anita C. Moore ,
Angela C. Comer  and
Jon P. Furuno
Anthony D. Harris*
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland Veterans Affairs Maryland Health Care System, Baltimore, Maryland
J. Kristie Johnson
Affiliation:
Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland
Kerri A. Thom
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland Veterans Affairs Maryland Health Care System, Baltimore, Maryland
Daniel J. Morgan
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland Veterans Affairs Maryland Health Care System, Baltimore, Maryland
Jessina C. McGregor
Affiliation:
College of Pharmacy, Oregon State University/Oregon Health and Science University, Portland, Oregon
Adebola O. Ajao
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland
Anita C. Moore
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland
Angela C. Comer
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland
Jon P. Furuno
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland
*
University of Maryland School of Medicine, Department of Epidemiology and Public Health, 685 West Baltimore Street, Room 330, Baltimore, MD 21201 (aharris@epi.umaryland.edu)
Get access Rights & Permissions [Opens in a new window]

Extract

Risk factors for development of intestinal colonization by imipenem-resistant Pseudomonas aeruginosa (IRPA) may differ between those who acquire the organism via patient-to-patient transmission versus by antibiotic selective pressure. The aim of this study was to quantify potential risk factors for the development of IRPA not due to patient-to-patient transmission.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 32 , Issue 7 , July 2011 , pp. 719 - 722
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2011

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Hidron, AI, Edwards, JR, Patel, J, et al. NHSN annual update: antimicrobial-resistant pathogens associated with healthcare-associated infections: annual summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2006–2007. Infect Control Hosp Epidemiol 2008;29:996–1011.Google Scholar
2.Bonten, MJ, Slaughter, S, Ambergen, AW, et al. The role of “colonization pressure” in the spread of vancomycin-resistant enterococci: an important infection control variable. Arch Intern Med 1998;158:1127–1132.CrossRefGoogle ScholarPubMed
3.Lepelletier, D, Caroff, N, Riochet, D, et al. Role of hospital stay and antibiotic use on Pseudomonas aeruginosa gastrointestinal colonization in hospitalized patients. Eur J Clin Microbiol Infect Dis 2006;25:600–603.CrossRefGoogle ScholarPubMed
4.Pena, C, Guzman, A, Suarez, C, et al. Effects of carbapenem exposure on the risk for digestive tract carriage of intensive care unit-endemic carbapenem-resistant Pseudomonas aeruginosa strains in critically ill patients. Antimicrob Agents Chemother 2007;51:1967–1971.Google Scholar
5.Johnson, JK, Smith, G, Lee, MS, et al. The role of patient-to-patient transmission in the acquisition of imipenem-resistant Pseudomonas aeruginosa colonization in the intensive care unit. J Infect Dis 2009;200:900–905.CrossRefGoogle ScholarPubMed
6.Harris, AD, Karchmer, TB, Carmeli, Y, Samore, MH. Methodological principles of case-control studies that analyzed risk factors for antibiotic resistance: a systematic review. Clin Infect Dis 2001;32:1055–1061.CrossRefGoogle ScholarPubMed
7.Lankford, MG, Collins, S, Youngberg, L, Rooney, DM, Warren, JR, Noskin, GA. Assessment of materials commonly utilized in health care: implications for bacterial survival and transmission. Am J Infect Control 2006;34:258–263.Google Scholar
8.Panagea, S, Winstanley, C, Walshaw, MJ, Ledson, MJ, Hart, CA. Environmental contamination with an epidemic strain of Pseudomonas aeruginosa in a Liverpool cystic fibrosis centre, and study of its survival on dry surfaces. J Hosp Infect 2005;59:102–107.Google Scholar
9.Kollef, MH. Broad-spectrum antimicrobials and the treatment of serious bacterial infections: getting it right up front. Clin Infect Dis 2008;47(suppl 1):S3–S13.CrossRefGoogle ScholarPubMed
10.Thom, KA, Johnson, JA, Strauss, SM, Furuno, JP, Perencevich, EN, Harris, AD. Increasing prevalence of gastrointestinal colonization with ceftazidime-resistant gram-negative bacteria among intensive care unit patients. Infect Control Hosp Epidemiol 2007;28:1240–1246.Google Scholar